Candidate List of substances of very high concern for Authorisation

(published in accordance with Article 59(10) of the REACH Regulation)

Candidate List of substances of very high concern for Authorisation

Notes:

Authentic version: Only the Candidate List published on this website is deemed authentic. Companies may have immediate legal obligations following the inclusion of a substance in the Candidate List on this website including in particular Articles 7, 31 and 33 of the REACH Regulation.
Numerical identifiers: Each candidate list entry covers both anhydrous and hydrated forms of a substance. The CAS number shown in an entry is typically for the anhydrous form. Hydrated forms of the substance identified by other CAS numbers are still within the scope of the entry.
Other numerical identifiers: For those entries with "-" in the EC number and CAS number columns, a non-exhaustive inventory of EC and/or CAS Registry numbers describing substances or groups of substances considered to fall within the scope of the Candidate List entry is included, where practicably possible. This information can be accessed through the "Details" button of the selected entry.

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Showing 1 - 50 of 240 results.

Substance name	EC No.	CAS No.	Date of inclusion	Reason for inclusion	Decision
1,2,3-trichloropropane	202-486-1	96-18-4	20-Jun-2011	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/31/2011	Details
1,2-dichloroethane	203-458-1	107-06-2	19-Dec-2011	Carcinogenic (Article 57a)	ED/77/2011	Details
1,3-propanesultone	214-317-9	1120-71-4	17-Dec-2015	Carcinogenic (Article 57a)	ED/79/2015	Details
1,4-dioxane	204-661-8	123-91-1	08-Jul-2021	Carcinogenic (Article 57a) Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)	D(2021)4569-DC	Details
2,2',6,6'-tetrabromo-4,4'-isopropylidenediphenol	201-236-9	79-94-7	17-Jan-2023	Carcinogenic (Article 57a)	D(2022)9120-DC	Details
2,2'-dichloro-4,4'-methylenedianiline	202-918-9	101-14-4	19-Dec-2011	Carcinogenic (Article 57a)	ED/77/2011	Details
2,2-bis(bromomethyl)propane-1,3-diol (BMP); 2,2-dimethylpropan-1-ol, tribromo derivative/3-bromo-2,2-bis(bromomethyl)-1-propanol (TBNPA); 2,3-dibromo-1-propanol (2,3-DBPA) show/hide 2,2-bis(bromomethyl)propane-1,3-diol (BMP) EC No.: 221-967-7 \| CAS No.: 3296-90-0 2,2-dimethylpropan-1-ol, tribromo derivative (TBNPA) EC No.: 253-057-0 \| CAS No.: 36483-57-5 3-bromo-2,2-bis(bromomethyl)-1-propanol (TBNPA) EC No.: - \| CAS No.: 1522-92-5 2,3-dibromo-1-propanol (2,3-DBPA) EC No.: 202-480-9 \| CAS No.: 96-13-9	-	-	08-Jul-2021	Carcinogenic (Article 57a)	D(2021)4569-DC	Details
2,4-dinitrotoluene	204-450-0	121-14-2	13-Jan-2010	Carcinogenic (Article 57a)	ED/68/2009	Details
2-Methoxyaniline, o-Anisidine	201-963-1	90-04-0	19-Dec-2011	Carcinogenic (Article 57a)	ED/77/2011	Details
4,4'- Diaminodiphenylmethane (MDA)	202-974-4	101-77-9	28-Oct-2008	Carcinogenic (Article 57a)	ED/67/2008	Details
4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)	209-218-2	561-41-1	18-Jun-2012	Carcinogenic (Article 57a)	ED/87/2012	Details
4,4'-bis(dimethylamino)benzophenone (Michler’s ketone)	202-027-5	90-94-8	18-Jun-2012	Carcinogenic (Article 57a)	ED/87/2012	Details
4,4'-methylenedi-o-toluidine	212-658-8	838-88-0	19-Dec-2012	Carcinogenic (Article 57a)	ED/169/2012	Details
4,4'-oxydianiline and its salts show/hide 4,4'-oxydianiline EC No.: 202-977-0 \| CAS No.: 101-80-4	-	-	19-Dec-2012	Carcinogenic (Article 57a) Mutagenic (Article 57b)	ED/169/2012	Details
4-aminoazobenzene	200-453-6	60-09-3	19-Dec-2012	Carcinogenic (Article 57a)	ED/169/2012	Details
4-methyl-m-phenylenediamine (toluene-2,4-diamine)	202-453-1	95-80-7	19-Dec-2012	Carcinogenic (Article 57a)	ED/169/2012	Details
6-methoxy-m-toluidine (p-cresidine)	204-419-1	120-71-8	19-Dec-2012	Carcinogenic (Article 57a)	ED/169/2012	Details
[4-[4,4'-bis(dimethylamino) benzhydrylidene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium chloride (C.I. Basic Violet 3) with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)	208-953-6	548-62-9	18-Jun-2012	Carcinogenic (Article 57a)	ED/87/2012	Details
[4-[[4-anilino-1-naphthyl][4-(dimethylamino)phenyl]methylene]cyclohexa-2,5-dien-1-ylidene] dimethylammonium chloride (C.I. Basic Blue 26) with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)	219-943-6	2580-56-5	18-Jun-2012	Carcinogenic (Article 57a)	ED/87/2012	Details
Acids generated from chromium trioxide and their oligomers show/hide Chromic acid EC No.: 231-801-5 \| CAS No.: 7738-94-5 Oligomers of chromic acid and dichromic acid EC No.: - \| CAS No.: - Dichromic acid EC No.: 236-881-5 \| CAS No.: 13530-68-2	-	-	15-Dec-2010	Carcinogenic (Article 57a)	ED/95/2010	Details
Acrylamide	201-173-7	79-06-1	30-Mar-2010	Carcinogenic (Article 57a) Mutagenic (Article 57b)	ED/68/2009	Details
Aluminosilicate Refractory Ceramic Fibres are fibres covered by index number 650-017-00-8 in Annex VI, part 3, table 3.1 of Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, and fulfil the three following conditions: a) oxides of aluminium and silicon are the main components present (in the fibres) within variable concentration ranges b) fibres have a length weighted geometric mean diameter less two standard geometric errors of 6 or less micrometres (µm) c) alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content less or equal to 18% by weight show/hide Refractories, fibers, aluminosilicate EC No.: - \| CAS No.: 142844-00-6	-	-	19-Dec-2011	Carcinogenic (Article 57a)	ED/77/2011 ED/95/2012	Details
Ammonium dichromate	232-143-1	7789-09-5	18-Jun-2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c)	ED/30/2010	Details
Anthracene oil -	292-602-7	90640-80-5	13-Jan-2010	Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e)	ED/68/2009	Details
Anthracene oil, anthracene paste -	292-603-2	90640-81-6	13-Jan-2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) PBT (Article 57d) vPvB (Article 57e)	ED/68/2009	Details
Anthracene oil, anthracene paste, anthracene fraction -	295-275-9	91995-15-2	13-Jan-2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) PBT (Article 57d) vPvB (Article 57e)	ED/68/2009	Details
Anthracene oil, anthracene paste, distn. lights -	295-278-5	91995-17-4	13-Jan-2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) PBT (Article 57d) vPvB (Article 57e)	ED/68/2009	Details
Anthracene oil, anthracene-low -	292-604-8	90640-82-7	13-Jan-2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) PBT (Article 57d) vPvB (Article 57e)	ED/68/2009	Details
Arsenic acid	231-901-9	7778-39-4	19-Dec-2011	Carcinogenic (Article 57a)	ED/77/2011	Details
Benz[a]anthracene	200-280-6	56-55-3	15-Jan-2018	Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e)	ED/01/2018	Details
Benzo[def]chrysene (Benzo[a]pyrene)	200-028-5	50-32-8	20-Jun-2016	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) PBT (Article 57d) vPvB (Article 57e)	ED/21/2016	Details
Benzo[k]fluoranthene	205-916-6	207-08-9	15-Jan-2019	Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e)	ED/88/2018	Details
Biphenyl-4-ylamine	202-177-1	92-67-1	19-Dec-2012	Carcinogenic (Article 57a)	ED/169/2012	Details
Cadmium	231-152-8	7440-43-9	20-Jun-2013	Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/69/2013	Details
Cadmium carbonate	208-168-9	513-78-0	15-Jan-2018	Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/01/2018	Details
Cadmium chloride show/hide cadmium chloride (CdCl2), hydrate (2:5) EC No.: 640-998-0 \| CAS No.: 7790-78-5	233-296-7	10108-64-2	16-Jun-2014	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/49/2014	Details
Cadmium fluoride	232-222-0	7790-79-6	17-Dec-2014	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/108/2014	Details
Cadmium hydroxide	244-168-5	21041-95-2	15-Jan-2018	Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/01/2018	Details
Cadmium nitrate	233-710-6	10325-94-7	15-Jan-2018	Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/01/2018	Details
Cadmium oxide show/hide Monteponite (CdO) EC No.: - \| CAS No.: 12139-21-8	215-146-2	1306-19-0	20-Jun-2013	Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/69/2013	Details
Cadmium sulphate show/hide Sulfuric acid, cadmium salt (1:1), hydrate EC No.: 626-360-4 \| CAS No.: 15244-35-6 Sulfuric acid, cadmium salt, hydrate (3:3:8) EC No.: 616-572-5 \| CAS No.: 7790-84-3	233-331-6	10124-36-4, 31119-53-6	17-Dec-2014	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/108/2014	Details
Cadmium sulphide	215-147-8	1306-23-6	16-Dec-2013	Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/121/2013	Details
Calcium arsenate	231-904-5	7778-44-1	19-Dec-2011	Carcinogenic (Article 57a)	ED/77/2011	Details
Chromium trioxide	215-607-8	1333-82-0	15-Dec-2010	Carcinogenic (Article 57a) Mutagenic (Article 57b)	ED/95/2010	Details
Chrysene	205-923-4	218-01-9	15-Jan-2018	Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e)	ED/01/2018	Details
Cobalt dichloride	231-589-4	7646-79-9	28-Oct-2008	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/31/2011 ED/67/2008	Details
Cobalt(II) carbonate	208-169-4	513-79-1	15-Dec-2010	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/95/2010	Details
Cobalt(II) diacetate	200-755-8	71-48-7	15-Dec-2010	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/95/2010	Details
Cobalt(II) dinitrate	233-402-1	10141-05-6	15-Dec-2010	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/95/2010	Details
Cobalt(II) sulphate	233-334-2	10124-43-3	15-Dec-2010	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/95/2010	Details

Showing 1 - 50 of 240 results.

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Candidate List of substances of very high concern for Authorisation

Candidate List of substances of very high concern for Authorisation

(published in accordance with Article 59(10) of the REACH Regulation)

Candidate List of substances of very high concern for Authorisation

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