Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
308-714-7
CAS no.:
98219-47-7
Index number:
649-393-00-6
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Organic
Registered compositions:
3
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance causes damage to organs through prolonged or repeated exposure, is very toxic to aquatic life with long lasting effects, is toxic in contact with skin, is toxic if inhaled, is toxic if swallowed, is very toxic to aquatic life, is suspected of damaging fertility or the unborn child, causes serious eye irritation, is a highly flammable liquid and vapour, may cause respiratory irritation, causes skin irritation, may cause an allergic skin reaction and may cause drowsiness or dizziness.

Breakdown of all 24 C&L notifications submitted to ECHA

Repr. 2 H361
Aquatic Chronic 2 H411
Eye Irrit. 2 H319
STOT RE 1 H372
Acute Tox. 4 H312
STOT RE 2 H373
STOT SE 3 H335
Asp. Tox. 1 H304 Harmonised Classification
Acute Tox. 3 H331
Muta. 1B H340 Harmonised Classification
Carc. 1A H350
Aquatic Acute 1 H400
Aquatic Chronic 1 H410
Acute Tox. 4 H302
Acute Tox. 4 H332
https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Carcinogenic (25% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Mutagenic (25% of REACH registrations).
  • Ss
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Skin sensitising (25% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 3 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 per annum.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and transfer of chemicals.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, laboratory work and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates) and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; take actions to prevent static discharges; do not breathe the dust, fume, gas, mist, vapours or spray; contaminated work clothing should not be allowed out of the workplace; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use only outdoors or in a well-ventilated area; obtain special instructions before use; do not eat, drink or smoke when using this product; avoid release to the environment; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier; avoid breathing the dust, fume, gas, mist, vapours or spray.

Response statements

In case of incident: Wash contaminated clothing before reuse. If swallowed: immediately call a poison center or doctor/physician. If exposed or concerned: get medical advice/attention. Get medical advice/attention if you feel unwell. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Collect spillage. If swallowed: rinse mouth. Do not induce vomiting. If inhaled: call a poison center or doctor/physician if you feel unwell. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. If eye irritation persists get medical advice/attention. Rinse the mouth. Do not induce vomiting. If swallowed: call a poison center or doctor/physician if you feel unwell. Follow specific treatment (see label).

Storage statements

Store this substance in a dry place; locked up; in a well-ventilated place and keeping container tightly closed.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Total Olefins Antwerp, Scheldelaan 10 2030 Antwerpen Belgium
  • Total Petrochemicals & Refining SA, Rue de l'Industrie,52 1040 Bruxelles Belgium
  • Total Raffinage France, 2, place Jean Millier, La Défense 92400 Courbevoie France

Substance names and other identifiers

[A complex combination of hydrocarbons obtained by the treatment and distillation of light steam-cracked petroleum naphtha. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C6 and boiling in the range of approximately 35°C to 80°C (95°F to 176°F).]
A complex combination of hydrocarbons obtained by the treatment and distillation of light steam-cracked petroleum naphtha. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C6 and boiling in the range of approximately 35°C to 80°C (95°F to 176°F).
C&L Inventory
Low boiling point naphtha - unspecified
A complex combination of hydrocarbons obtained by the treatment and distillation of light steam-cracked petroleum naphtha. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C6 and boiling in the range of approximately 35°C to 80°C (95°F to 176°F).
C&L Inventory
Naphtha (petroleum), light steam-cracked, thermally treated
EC Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), light steam-cracked, thermally treated
A complex combination of hydrocarbons obtained by the treatment and distillation of light steam-cracked petroleum naphtha. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C6 and boiling in the range of approximately 35°C to 80°C (95°F to 176°F).
C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
Naphtha (petroleum), light steam-cracked, thermally treated; Low boiling point naphtha -unspecified [ complex combination of hydrocarbons obtained by the treatment and distillation of light steam-cracked petroleum naphtha. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C6 and boiling in the range of approximately 35 o C to 80 o C (95 °F to 176 °F).]
A complex combination of hydrocarbons obtained by the treatment and distillation of light steam-cracked petroleum naphtha. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C6 and boiling in the range of approximately 35°C to 80°C (95°F to 176°F).
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Naphtha (petroleum), light steam-cracked, thermally treated; Low boiling point naphtha -unspecified
A complex combination of hydrocarbons obtained by the treatment and distillation of light steam-cracked petroleum naphtha. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C6 and boiling in the range of approximately 35°C to 80°C (95°F to 176°F).
FCM Active and Intelligent Materials - CMRs not allowed for use, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Workplace Signs - minimum requirements & signs on containers and pipes, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes
(Keerulise koostisega süsivesinike segu, mis saadakse kerge aurkrakitud raskbensiini töötlemisel ja destilleerimisel. Koosneb peamiselt süsivesinikest, mille süsiniku aatomite arv on valdavalt vahemikus C5 kuni C6, ning on keemistemperatuuriga umbes 35°C kuni 80 °C.) (et)
C&L Inventory
(Složeni sastav ugljikovodika dobiven obradom i destilacijom lakog parno krekiranog naftnog benzina. Sastoji se pretežito od ugljikovodika koji imaju broj ugljikovih atoma pretežito u području od C5 do C6 i vriju u području približno od 35 °C do 80 °C.) (hr)
C&L Inventory
[Kompleks blanding av hydrokarboner dannet ved behandling og destillasjon av lett, dampkrakket petroleumsnafta. Består for det meste av hydrokarboner, hovedsakelig C5 til C6, med omtrentlig kokepunktsintervall fra 35 °C til 80 °C (95 °F til 176 °F).] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov dobljena z obdelavo in destilacijo lahke, parno krekirane nafte zemeljskega olja. Sestoji pretežno iz ogljikovodikov s številom ogljikovih atomov pretežno v območju med C5 in C6 ter z vreliščem v območju med 35 °C in 80 °C.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen, erhalten durch Behandlung und Destillation von leichtem dampfgekracktem Naphtha; besteht vorwiegend aus Kohlenwasserstoffen mit Kohlenstoffzahlen überwiegend im Bereich von C5 bis C6 mit einem Siedebereich von etwa 35 °C bis 80 °C] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov získavaná úpravou a destiláciou ľahkej frakcie z parného krakovania ťažkého benzínu. Pozostáva predovšetkým z uhľovodíkov s počtom atómov uhlíka prevažne v rozmedzí od C5 do C6. Má teplotu varu v rozmedzí približne od 35 °C do 80 °C.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi obţinută prin tratarea şi distilarea fracţiei nafta petrolică uşoară cracată cu vapori. Constă predominant în hidrocarburi având un număr de atomi de carbon cuprins între C5 şi C6 şi cu punct de fierbere cuprins între aproximativ 35°C şi 80°C (95°F şi 176°F).] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts, apstrādājot un destilējot vieglos ligroīna naftas tvaika krekinga produktus. Sastāv pārsvarā no ogļūdeņražiem ar oglekļa atomu skaitu pārsvarā no C5 līdz C6, aptuvenā viršanas temperatūra no 35°C līdz 80°C (95°F līdz 176°F).] (lv)
C&L Inventory
[Složitá směs uhlovodíků získaná zpracováním a destilací lehkého pyrolyzního ropného benzínu. Je složena převážně z uhlovodíků s počtem uhlíkových atomů převážně v rozmezí C5 až C6 a s rozmezím teplot varu přibližně 35 °C až 80 °C.] (cs)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas apdorojant ir distiliuojant lengvąjį krekingo vandens garais pirminį benziną. Jį sudaro daugiausia angliavandeniliai, turintys anglies atomų skaičių daugiausia nuo C5 iki C6, ir kurių virimo temperatūra maždaug nuo 35 °C iki 80 °C (nuo 95 °F iki 176 °F).] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet könnyű gőzkrakkolt nyersolaj benzin kezelésével és desztillációjával nyernek. Főleg szénhidrogénekből áll, melyek szénatomszáma elsősorban a C5-C6 tartományban van, forrásponttartománya 35°C-tól 80°C-ig (95°F-től 176°F-ig) terjed.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων που λαμβάνεται από την κατεργασία και απόσταξη ελαφράς, ατμοπυρολυμένης νάφθας πετρελαίου. Συνίσταται κυρίως από υδρογονάνθρακες με αριθμό ατόμων άνθρακα κυρίως C5 και C6 που αποστάζουν μεταξύ 35 °C και 80 °C.] (el)
C&L Inventory
[Комплексна комбинация от въглеводороди, получена при обработване и дестилацията на леки нефтени дестилати от паров крекинг. Състои се основно от въглеводороди с брой на въглеродните атоми в интервала от С5 до С6 включително и с температура на кипене приблизително в интервала от 35 °С до 80 °С (95°F до 176°F).] (bg)
C&L Inventory
Alacsony forráspontú benzin – nem meghatározott (hu)
C&L Inventory
Benzin (nafta), laki parom krekiran, termički obrađen (hr)
C&L Inventory
Benzin (nyersolaj), könnyű gőzkrakkolt, hőkezelt (hu)
C&L Inventory
Benzyna lekka z krakingu parowego po obróbce termicznej (ropa naftowa) (pl)
C&L Inventory
Benzín (ropný), lehký pyrolýzní, tepelně zpracovaný (cs)
C&L Inventory
combinación compleja de hidrocarburos obtenida por el tratamiento y destilación de nafta ligera de petróleo craqueada a vapor; compuesta principalmente de hidrocarburos con un número de carbonos en su mayor parte dentro del intervalo de C5 a C6 y con un intervalo de ebullición aproximado de 35 °C a 80 °C (es)
C&L Inventory
Combinaison complexe d'hydrocarbures produite par traitement et distillation de naphta léger de vapocraquage. Se compose principalement d'hydrocarbures dont le nombre de carbones se situe en majorité dans la gamme C5-C6 et dont le point d'ébullition est compris approximativement entre 35°C et 80°C. (fr)
C&L Inventory
Combinazione complessa di idrocarburi ottenuta per trattamento e distillazione di nafta di petrolio leggera sottoposta a steam cracking. È costituita in prevalenza da idrocarburi con numero di atomi di carbonio prevalentemente nell'intervallo C5-6 e punto di ebollizione nell'intervallo 35 °C - 80 °C ca. (da 95°F a 176°F). (it)
C&L Inventory
Combinação complexa de hidrocarbonetos obtida por tratamento e destilação de nafta petrolífera leve de steam cracking. É constituída predominantemente por hidrocarbonetos com número de átomos de carbono predominantemente na gama C5 a C6 e destilação no intervalo aproximado de 35 °C a 80 °C. (pt)
C&L Inventory
Een complexe verzameling koolwaterstoffen, verkregen door behandeling en destillatie van lichte stoomgekraakte aardolienafta. Bestaat voornamelijk uit koolwaterstoffen, overwegend C5 tot en met C6, met een kooktraject van ongeveer 35°C tot 80°C). (nl)
C&L Inventory
En sammensat blanding af carbonhydrider opnået ved behandling og destillation af let dampkrakket råolienaphtha. Den består overvejende af carbonhydrider, overvejende C5 til og med C6, med kogeinterval omtrent fra 35 °C til 80 °C (95 ºF til 176 ºF). (da)
C&L Inventory
Fracţia nafta (petrol), uşoară de cracare cu vapori, tratată termic (mt)
C&L Inventory
Fracţia nafta (petrol), uşoară de cracare cu vapori, tratată termic (ro)
C&L Inventory
Fracţia nafta cu punct de fierbere la temperaturi scăzute- nespecificat (mt)
C&L Inventory
Fracţia nafta cu punct de fierbere la temperaturi scăzute- nespecificat (ro)
C&L Inventory
Komplex blandning av kolväten erhållen genom behandling och destillation av lätt, ångkrackad petroleumnafta. Består av kolväten, främst C5 till C6, med ungefärligt kokpunktsintervall från 35 °C till 80 °C. (sv)
C&L Inventory
Lavtkogende uspecificeret nafta (da)
C&L Inventory
lavtkokende nafta - uspesifisert (no)
C&L Inventory
Ligroīns (nafta), vieglais, tvaika krekinga, termiski apstrādāts (lv)
C&L Inventory
Ligroīns ar zemu viršanas temperatūru – nestandarta (lv)
C&L Inventory
Lågkokande nafta – ospecificerad (sv)
C&L Inventory
Madala keemispunktiga raskbensiin – määratlemata (et)
C&L Inventory
Matalalla kiehuva teollisuusbensiini – täsmentämätön (fi)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu käsittelemällä ja tislaamalla kevyttä höyrykrakattua maaöljyteollisuusbensiiniä. Koostuu pääasiassa hiilivedyistä, joiden hiililuvut ovat pääasiassa välillä C5:stä C6:een ja jotka kiehuvat likimäärin välillä 35°C:sta 80°C:een (95°F:sta 176°F:iin). (fi)
C&L Inventory
Nafta (aardolie), lichte stoomgekraakte, thermisch behandeld (nl)
C&L Inventory
nafta (petroleum), lett, dampkrakket, termisk behandlet (no)
C&L Inventory
Nafta (petroleum), lätt, ångkrackad, värmebehandlad (sv)
C&L Inventory
nafta (petrolio), leggera da steam cracking, trattata termicamente (it)
C&L Inventory
nafta (petróleo), fracción ligera craqueada a vapor, tratada térmicamente (es)
C&L Inventory
Nafta (petróleo), fracção leve de steam cracking, tratada termicamente (pt)
C&L Inventory
nafta (zemeljsko olje), lahka, parno krekirana, termično obdelana (sl)
C&L Inventory
nafta con basso punto di ebollizione - non specificata (it)
C&L Inventory
Nafta de baixo ponto de ebulição - não especificada (pt)
C&L Inventory
nafta de bajo punto de ebullición, sin especificar (es)
C&L Inventory
Nafta met laag kookpunt - niet gespecifieerd (nl)
C&L Inventory
nafta z nizkim vreliščem – neopredeljeno (sl)
C&L Inventory
Naphta léger (pétrole), vapocraquage, traitement thermique;naphta à bas point d'ébullition — non spécifié;[combinaison complexe d'hydrocarbures obtenue par traitement et distillation d'un naptha léger de vapocraquage. Se compose principalement d'hydrocarbures comportant majoritairement entre 5 et 6 atomes de carbone (C4-C12) et dont l'intervalle d'ébullition est compris approximativement entre 35 et 80 oC (entre 95 et 176o F).] (fr)
C&L Inventory
naphta à point d'ébullition bas - non spécifié (fr)
C&L Inventory
Naphtha (Erdöl), leicht, dampfgekrackt, thermisch behandelt (de)
C&L Inventory
naphtha (råolie), let dampkrakket, termisk behandlet (da)
C&L Inventory
Naphtha, niedrigsiedend, nicht spezifiziert (de)
C&L Inventory
Nisko-vrijući benzin - nespecificiran (hr)
C&L Inventory
Niskowrząca benzyna - niespecyfikowana (pl)
C&L Inventory
Nízkovroucí benzínová frakce – nespecifikovaná (cs)
C&L Inventory
O combinaţie complexă de hidrocarburi obţinută prin tratarea şi distilarea fracţiei nafta petrolică uşoară cracată cu vapori. Constă predominant în hidrocarburi având un număr de atomi de carbon cuprins între C5 şi C6 şi cu punct de fierbere cuprins între aproximativ 35°C şi 80°C (95°F şi 176°F). (mt)
C&L Inventory
Pirminis benzinas (nafta), lengvasis krekingo vandens garais, termiškai apdorotas (lt)
C&L Inventory
Raskbensiin (nafta), kerge aurkrakitud, termiliselt töödeldud (et)
C&L Inventory
Teollisuusbensiini (maaöljy), kevyt höyrykrakattu, lämmöllä käsitelty (fi)
C&L Inventory
Złożona mieszanina węglowodorów otrzymywana przez obróbkę i destylację odbenzenowanej lekkiej benzyny krakowanej z parą wodną. Składa się przede wszystkim z węglowodorów o liczbie atomów węgla głównie w zakresie od C5 do C6, wrzących w zakresie temp. od ok. 35°C do 80°C. (pl)
C&L Inventory
ťažký benzín (ropný), z ľahkej frakcie z parného krakovania, tepelne upravený (sk)
C&L Inventory
ťažký benzín s nízkou teplotou varu - nešpecifikovaný (sk)
C&L Inventory
Žematemperatūris pirminis benzinas – neapibrėžtas (lt)
C&L Inventory
Νάφθα χαμηλού σημείου ζέσεως - μη προσδιοριζόμενη (el)
C&L Inventory
νάφθαΝάφθα (πετρελαίου), ελαφρά, ατμοπυρολυμένη, θερμικά κατεργασμένη (el)
C&L Inventory
Нискооктанов бензин (нефт), лек, от паров крекинг, термично обработен (bg)
C&L Inventory
Нискооктанов бензин с ниска температура на кипене-неспецифициран (bg)
C&L Inventory
Naphtha (petroleum), light steam-cracked, thermally treated
Other
Naphta (petroleum), light steam cracked, thermally treated
Registration dossier
Naphtha (petroleum), light steam-cracked, thermally treated
Registration dossier
Essence de pyrolyse hydrogenee
Registration dossier
Essence de pyrolyse hydrogénée
Registration dossier
Essence hydrogenee exterieure
Registration dossier
Essences hydrogenees
Registration dossier
Essences hydrogénées
Registration dossier
Hydrotreated pyrolysis gasoline
Registration dossier
Pygas
Registration dossier
649-393-00-6
Index number
C&L Inventory
98219-47-7
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 24 studies submitted
  • 23 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [23]
C Form
Other (89%), Viscous (11%) [9]
C Odour
Characteristic of aromatic compounds (76%), Other (19%) [21]
C Substance type
Petroleum product (62%), Organic (38%) [21]

Type of Study provided
Studies with data
Key study 6 17
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 7 studies submitted
  • 6 studies processed
R Melting / freezing point
-100 - -29 °C @ 101.3 kPa [8]

Type of Study provided
Studies with data
Key study 6
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-66.9 °C

Boiling point

Study results
  • 21 studies submitted
  • 13 studies processed
R Boiling point
54.3 - 260 °C @ 100.7 - 101.33 kPa [15]

Type of Study provided
Studies with data
Key study 9 5
Supporting study 1 6
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
142 °C

Density

Study results
  • 13 studies submitted
  • 5 studies processed
R Relative density
0.83 - 0.89 @ 20 °C [5]

Type of Study provided
Studies with data
Key study 6
Supporting study 1 6
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
0.87

Vapour pressure

Study results
  • 29 studies submitted
  • 21 studies processed
R Vapour pressure
4 - 550 hPa @ 20 - 50 °C [29]

Type of Study provided
Studies with data
Key study 21
Supporting study 3 5
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
11.14 kPa @ 20 °C

Partition coefficient

Study results
  • 9 studies submitted
  • 7 studies processed
R Log Pow
2.2 - 6.5 @ -248.15 - 25 °C and pH 6.2 - 7 [7]

Type of Study provided
Studies with data
Key study 7
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
5.84 @ 20 °C

Water solubility

Study results
  • 6 studies submitted
  • 6 studies processed
R Water solubility (mass/vol.)
25 - 600 mg/L @ 20 °C and pH 5.2 - 9.1 [5]
R Water solubility (vol%)
0.1 - 0.7 vol% @ 20 °C and pH 6.4 [2]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
290 mg/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
71.1 mN/m @ 243 mg/L

Flash point

Study results
  • 7 studies submitted
  • 7 studies processed
R Flash point
-30 - 43 °C @ 101.3 kPa [9]

Type of Study provided
Studies with data
Key study 7
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
7.4 °C

Auto flammability

Study results
  • 6 studies submitted
  • 6 studies processed
R Autoflammability / self-ignition
401 - 502 °C @ 101.3 kPa [6]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
429 °C

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 7 studies submitted
  • 6 studies processed
R dynamic viscosity (in mPa s)
0.45 - 0.95 [10]
R kinematic viscosity (in mm²/s)
0.54 - 1.5 [13]

Type of Study provided
Studies with data
Key study 6
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
0.723 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
1 112

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air Hazard related to composition of atmosphere identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 1 mg/L [1]
LL50 (4 days) 1.1 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 1.2 - 2.7 mg/L [2]
EL50 (48 h) 1.2 - 3.3 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (4 days) 910 - 1 800 µg/L [4]
EC50 (72 h) 1.3 - 2 mg/L [2]
NOEC (4 days) 120 µg/L [1]
EL50 (4 days) 1.2 - 2.2 mg/L [4]
EL50 (72 h) 1.5 - 2.3 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 3.25 mg/m³ carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 23.4 mg/kg bw/day carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 3.25 µg/m³ carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 464 ng/kg bw/day carcinogenicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 17 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 5 1
Supporting study 6 2
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal absorption
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study 3 3
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
Low bioaccumulation potential
Absorption values
Oral: 100 %
Dermal: 1 %
Inhalation: 50 %

Acute toxicity

Study results
oral
  • 8 studies submitted
  • 8 studies processed
P/RResults
LD50 512 - 6 631 mg/kg bw (rat) [10]
LD50 5 251 - 5 627 mg/kg bw (mouse) [2]
M/CInterpretations of results
Practically nontoxic [1]

Type of Study provided
oral
Studies with data
Key study 8
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 9 studies submitted
  • 9 studies processed
P/RResults
LC50 (6 h) 1.723 mg/L air (rat) [1]
LC50 (6 h) 284 - 353 ppm (rat) [2]
LC50 (4 h) 5.14 - 43.767 mg/L air (rat) [6]
LC50 (4 h) 5 922 - 13 700 ppm (rat) [6]
LC50 (6 h) 738.5 mg/m³ air (mouse) [1]
M/CInterpretations of results
Toxic [2]

inhalation
Studies with data
Key study 8 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 7 studies submitted
  • 7 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
LD50 2 000 - 12 126 mg/kg bw (rabbit) [4]
LD50 5 000 mL/kg bw (rabbit) [1]
M/CInterpretations of results
Practically nontoxic [2]

dermal
Studies with data
Key study 6
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 20 000 mg/m³
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2 5
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: eye
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 3 1
Supporting study
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 4
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 12 studies submitted
  • 8 studies processed
P/RResults
NOAEL (rat): 4 - 625 mg/kg bw/day [9]
NOAEL (mouse): 625 mg/kg bw/day [1]
LOAEL (rat): 25 - 1 250 mg/kg bw/day [4]
LOAEL (mouse): 1 250 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 6 2
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: inhalation
  • 15 studies submitted
  • 13 studies processed
P/RResults
NOAEC (rat): 96 - 2 355 mg/m³ air [3]
NOAEC (rat): 30 - 7 000 ppm [12]
NOAEC (mouse): 32 - 96 mg/m³ air [2]
NOAEC (mouse): 5 - 2 000 ppm [5]
LOAEC (rat): 2.261 - 4.71 mg/L air [2]

Study data: inhalation
Studies with data
Key study 11 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed LOAEL 25 mg/kg bw/day (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 18 4
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 13 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 4 7
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVivo
Adverse effect observed (positive)

Carcinogenicity

Study results
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 7 5
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LOAEL 25 mg/kg bw/day (chronic, rat)
Inhalation route:
Adverse effect observed LOAEC 960 mg/m³ (chronic, mouse)

Toxicity to reproduction

Study results
Study data: reproduction
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 6 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 11 3
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Study results
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 4 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant