Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name:
  • IUPAC name: 1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; 1-methyl-4-(propan-2-yl)cyclohexa-1,4-diene; 2,2-dimethyl-3-methylidenebicyclo[2.2.1]heptane; 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene; 3,7,7-trimethylbicyclo[4.1.0]hept-3-ene; 4-methoxy-6-(prop-2-en-1-yl)-2H-1,3-benzodioxole; 4-methyl-1-(propan-2-yl)cyclohex-3-en-1-ol; 4-methylidene-1-(propan-2-yl)bicyclo[3.1.0]hexane; 6,6-dimethyl-2-methylidenebicyclo[3.1.1]heptane; 7-methyl-3-methylideneocta-1,6-diene
  • Substance names and other identifiers
EC / List no.:
282-013-3
CAS no.:
84082-68-8
Index number:
Molecular formula:
C101H158O4
SMILES:
CC(C)C1=CCC(C)=CC1.CC(C)C12CC1C(=C)CC2.CC(C)=CCCC(=C)C=C.CC(=C)C1CCC(C)=CC1.CC1=CCC2C(C1)C2(C)C.CC1=CCC2CC1C2(C)C.CC1(C)C2CC1C(=C)CC2.CC1(C)C2CCC(C2)C1=C.CC(C)C1(O)CCC(C)=CC1.COC1=CC(CC=C)=CC2=C1OCO2
InChI:
InChI=1/C11H12O3.C10H18O.8C10H16/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11;1-8(2)10(11)6-4-9(3)5-7-10;1-7-8-4-5-9(6-8)10(7,2)3;2*1-7-4-5-8-6-9(7)10(8,2)3;1-7-4-5-8-9(6-7)10(8,2)3;1-7(2)10-5-4-8(3)9(10)6-10;2*1-8(2)10-6-4-9(3)5-7-10;1-5-10(4)8-6-7-9(2)3/h3,5-6H,1,4,7H2,2H3;4,8,11H,5-7H2,1-3H3;8-9H,1,4-6H2,2-3H3;4,8-9H,5-6H2,1-3H3;8-9H,1,4-6H2,2-3H3;4,8-9H,5-6H2,1-3H3;7,9H,3-6H2,1-2H3;4,7-8H,5-6H2,1-3H3;4,10H,1,5-7H2,2-3H3;5,7H,1,4,6,8H2,2-3H3
Type of substance:
UVCB
Origin:
Other
Registered compositions:
12
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the classification provided by companies to ECHA in REACH registrations this substance may be fatal if swallowed and enters airways, may cause cancer, is toxic to aquatic life with long lasting effects, is a flammable liquid and vapour, is suspected of causing genetic defects and may cause an allergic skin reaction.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is very toxic to aquatic life with long lasting effects, is very toxic to aquatic life and causes skin irritation.

Breakdown of all 1492 C&L notifications submitted to ECHA

Skin Sens. 1 H317
Flam. Liq. 3 H226
Asp. Tox. 1 H304
Muta. 2 H341
Carc. 1B H350
Aquatic Chronic 1 H410
Skin Irrit. 2 H315
Aquatic Acute 1 H400
Aquatic Chronic 2 H411
Not Classified
Eye Irrit. 2 H319
Carc. 2 H351
Carc. 1A H350
Aquatic Chronic 3 H412
Flam. Liq. 2 H226
https://echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (100% of REACH registrations).
  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (100% of REACH registrations).

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 25 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 10 - 100 tonnes per year.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: air care products, biocides (e.g. disinfectants, pest control products), perfumes and fragrances, washing & cleaning products and cosmetics and personal care products.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: perfumes and fragrances.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, non-industrial spraying, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, roller or brushing applications, mixing in open batch processes, treatment of articles by dipping and pouring and hand mixing with intimate contact only with personal protective equipment available.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid.

This substance is used in the following products: perfumes and fragrances.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, laboratory work, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, production of mixtures or articles by tabletting, compression, extrusion or pelletisation and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: perfumes and fragrances.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, industrial spraying, roller or brushing applications, treatment of articles by dipping and pouring and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites.

This substance is used in the following activities or processes at workplace: closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and transfer of chemicals at dedicated facilities.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use explosion-proof equipment (electrical/ventilating/lighting/etc.); avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. Do not induce vomiting.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Berje Trakia Ltd, 39 A Batenberg Street Floor 2 Office 10 4000 Ploudiv Bulgaria
  • CEHTRA Europe S.à.r.l., 20, Avenue Pasteur L-2310 - Luxembourg
  • CHARABOT, 10 avenue yves-emmanuel baudoin 06130 Grasse France
  • Duellberg Konzentra GmbH & Co. KG, Obenhauptstr.3 22335 Hamburg Hamburg Germany
  • elixens france SAS, 66-68 Avenue du château ZI du Vert Galant 95310 ST OUEN L'AUMONE France
  • Elixens UK Ltd, No 1 Essence House, Crabtree Road Thorpe Industrial Park TW20 8RN Egham Surrey United Kingdom
  • Enviresearch Portugal, Rua Fernando Pessoa 319, 2C 2775-515 Carcavelos Portugal
  • ERNESTO VENTOS, S.A., Carretera Reial 120B 08960 Sant Just Desvern Spain
  • FIRMENICH GRASSE SAS, Zi les Bois de Grasse Boulevard Emmanuel Rouquier 06130 GRASSE France
  • FIRMENICH GRASSE SAS OR 1, Parc Industriel Les Bois de Grasse 06130 Grasse France
  • Frey + Lau GmbH, Immenhacken 12 DE-24558 Henstedt-Ulzburg Germany
  • Givaudan France SAS - OR1, 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France
  • J C Buck Limited, Unit 8, The Stafford Estate Hillman Close, Ardleigh Green RM11 2SJ Hornchurch Essex United Kingdom
  • Johann Voegele KG, Bahnhofstrasse 143 74348 Lauffen Baden-Württemberg Germany
  • John Kellys (London) Ltd, Leyton Studios 15 Argall Avenue E10 7QE London United Kingdom
  • LLUCH ESSENCE, S.L., Lo Gaiter, 160 08820 EL PRAT DE LLOBREGAT CATALUÑA Spain
  • Payan Bertrand, 28 av Jean XXIII BP61057 06131 Grasse France
  • QUIMDIS SAS, 71, rue Anatole France 92532 Levallois-Perret France
  • Robertet, 37 Avenue Sidi Brahim 06130 Grasse France
  • Sensient Fragrances, S.A.U., Crta. Armilla Km 2,5 18100 Armilla Granada Spain
  • Stockmeier Química S.L.U, Alta Ribagorza, 6-8 08820 El Prat de Llobregat Barcelona Spain
  • Sustainability Support Services (Europe) AB, Markaskälsvägen 6 22647 Lund Sweden
  • Symrise AG, Mühlenfeldstraße 1 37603 Holzminden Germany
  • ULTRA INTERNATIONAL B.V., Malledijk 3H, 3208 LA Spijkenisse, (Loods 12-15) NETHERLANDS Netherlands
  • V. MANE FILS , 620 route de Grasse 06620 Le Bar sur Loup France
  • Moellhausen spa, Viale delle industrie 95 20040 Cambiago Italy

Substance names and other identifiers

Myristica fragrans, ext.
EC Inventory, REACH pre-registration
Oils, nutmeg
Other
1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; 1-methyl-4-(propan-2-yl)cyclohexa-1,4-diene; 2,2-dimethyl-3-methylidenebicyclo[2.2.1]heptane; 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene; 3,7,7-trimethylbicyclo[4.1.0]hept-3-ene; 4-methoxy-6-(prop-2-en-1-yl)-2H-1,3-benzodioxole; 4-methyl-1-(propan-2-yl)cyclohex-3-en-1-ol; 4-methylidene-1-(propan-2-yl)bicyclo[3.1.0]hexane; 6,6-dimethyl-2-methylidenebicyclo[3.1.1]heptane; 7-methyl-3-methylideneocta-1,6-diene
Registration dossier, Other
Essential oil extract of Myristica fragrans (Myristicaceae) seed
C&L Inventory
Essential oil extract of Myristica fragrans (Myristicaceae) seed Mace Oil Myristica fragrance, ext myristica fragrans houtt. fruit oil Myristica fragrans, essential oil Myristica fragrans, ext Myristica fragrans, ext. Myristica fragrans, Myristicaceae. Nutmeg essential oil NUTMEG OIL Nutmeg Oil (Myristica fragrance, ext.) Nutmeg Oil (Myristica fragrans, ext.) Nutmeg Oleoresin Nutmeg, essential oil
C&L Inventory
Mace Oil
C&L Inventory
Myristica fragrance, ext
Registration dossier
myristica fragrans houtt. fruit oil
C&L Inventory
Myristica fragrans, essential oil
C&L Inventory
Myristica fragrans, ext
C&L Inventory
Myristica fragrans, Myristicaceae.
C&L Inventory
Nutmeg essential oil
C&L Inventory
NUTMEG OIL
C&L Inventory, Registration dossier
Nutmeg Oil (Myristica fragrance, ext.)
Registration dossier
Nutmeg Oil (Myristica fragrans, ext.)
Registration dossier
Nutmeg Oleoresin
C&L Inventory
Nutmeg, essential oil
C&L Inventory
Young Living Nutmeg Essential Oil
C&L Inventory
Noce moscata
Registration dossier
Noix muscade
Registration dossier
Noz moscada
Registration dossier
Nuez Moscada
Registration dossier
Nutmeg DQ (AC) XN 41443TT
Registration dossier
Nutmeg Oil Indonesia
Registration dossier
Nutmeg Oil redist
Registration dossier
Nutmeg Oil Sri Lanka
Registration dossier
Nutmeg oleoresin 30%
Registration dossier
Nutmeg oleoresin 40%
Registration dossier
Nutmeg Pure
Registration dossier
Sri Lanka Organic Mace Oil
C&L Inventory
8008-45-5
CAS number
C&L Inventory, Other
84082-68-8
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Boiling point

Study results
  • 1 study submitted
  • 1 study processed
R Boiling point
167.7 °C @ 99.2 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Density

Study results
  • 2 studies submitted
  • 1 study processed
R Relative density
0.9 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Vapour pressure

Study results
  • 1 study submitted
  • 1 study processed
R Vapour pressure
3.794 hPa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Partition coefficient

Study results
  • 1 study submitted
  • 1 study processed
R Log Pow
2.65 - 4.88 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Water solubility

Study results
  • 1 study submitted
  • 1 study processed
R Water solubility (mass/vol.)
2.619 - 2 095 mg/L @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 1 study submitted
  • 1 study processed
R Flash point
44.7 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 1 study submitted
  • 1 study processed
R Autoflammability / self-ignition
270 °C @ 99 - 105 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Data not provided by the registrant

Viscosity

Data not provided by the registrant

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Data not provided by the registrant

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Data not provided by the registrant

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to fish

Data not provided by the registrant

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 590 µg/L [1]
EL50 (48 h) 4.2 mg/L [1]
EL50 (24 h) 5.8 mg/L [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
4.2 mg/L

Long–term toxicity to aquatic invertebrates

Data not provided by the registrant

Toxicity to aquatic algae and cyanobacteria

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EL10 (48 h) 910 - 3 900 µg/L [2]
EL50 (48 h) 5.3 - 15 mg/L [2]
NOELR (48 h) 320 - 1 000 µg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
15 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Data not provided by the registrant

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicokinetics, metabolism, and distribution

Data not provided by the registrant

Acute toxicity

Study results
oral
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
oral
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 h) 4.9 mg/L air (rat) [1]
M/CInterpretations of results
Not classified [1]

inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 0 studies submitted
  • 0 studies processed

No data available

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)

Repeated dose toxicity

Data not provided by the registrant

Genetic toxicity

Study results
Study data: in vitro
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 1 1
Supporting study 2
Weight of evidence
Other 4
Data waiving
no waivers
Study data: in vivo
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Data not provided by the registrant

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant