Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Ethyl acetate
  • IUPAC name: ethyl acetate
  • Other names
EC / List no.:
205-500-4
CAS no.:
141-78-6
Index number:
607-022-00-5
Molecular formula:
C4H8O2
SMILES:
CCOC(C)=O
InChI:
InChI=1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
23
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is a highly flammable liquid and vapour, causes serious eye irritation and may cause drowsiness or dizziness.

Breakdown of all 3677 C&L notifications submitted to ECHA

Flam. Liq. 2 H225 Harmonised Classification
STOT SE 3 H336 Harmonised Classification
Eye Irrit. 2 H319 Harmonised Classification
Flam. Liq. 2 H226
Aquatic Chronic 1 H410
STOT SE 3 H335
Not Classified
Asp. Tox. 1 H304
Acute Tox. 4 H302
Eye Irrit. 2A H319
Acute Tox. 4 H332
Aquatic Chronic 3 H412
Skin Sens. 1 H317
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • Ss

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 88 active registrations under REACH, 2 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100 000 - 1 000 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: coating products, cosmetics and personal care products, adhesives and sealants, fillers, putties, plasters, modelling clay, inks and toners, finger paints, plant protection products, leather treatment products and textile treatment products and dyes.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance can be found in complex articles, with no release intended: electrical batteries and accumulators.

This substance is used in the following products: coating products, laboratory chemicals, adhesives and sealants, inks and toners, anti-freeze products, leather treatment products, lubricants and greases and polishes and waxes.

This substance is used in the following areas: scientific research and development. This substance is used for the manufacture of: chemicals, fabricated metal products, electrical, electronic and optical equipment and machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, non-industrial spraying, closed, continuous processes with occasional controlled exposure, treatment of articles by dipping and pouring, batch processing in synthesis or formulation with opportunity for exposure, closed batch processing in synthesis or formulation, laboratory work and closed processes with no likelihood of exposure.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.

This substance is used in the following products: cosmetics and personal care products, coating products and perfumes and fragrances.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, laboratory work and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: coating products and laboratory chemicals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: building & construction work. This substance is used for the manufacture of: chemicals, plastic products, machinery and vehicles, textile, leather or fur, electrical, electronic and optical equipment and fabricated metal products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, laboratory work, industrial spraying, treatment of articles by dipping and pouring and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure, laboratory work and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: ground and bond container and receiving equipment; take actions to prevent static discharges; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use only outdoors or in a well-ventilated area; keep container tightly closed; use explosion-proof equipment (electrical/ventilating/lighting/etc.); wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier; use non-sparking tools; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; avoid breathing the dust, fume, gas, mist, vapours or spray.

Response statements

In case of incident: Call a poison center or doctor/physician if you feel unwell. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. In case of fire: Use (measures specified by manufacturer/supplier) for extinction. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. If eye irritation persists get medical advice/attention.

Storage statements

Store this substance in a well-ventilated place and Keeping it cool; locked up; in a well-ventilated place and keeping container tightly closed.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • Adhesives Research Ireland Limited, Raheen Business Park LK Limerick Limerick Ireland
  • ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
  • Avantor Performance Materials Poland S.A., Sowińskiego 11 44-100 Gliwice Poland
  • Avery Dennison Materials Europe BV, Willem Einthovenstraat 11 2342 BH Oegstgeest Zuid-Holland Netherlands
  • B-Lands Consulting (811322-5), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • B-Lands Consulting (811639-8), World Trade Center, 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
  • BASF Colors & Effects GmbH, An der Rheinschanze 1 67059 Ludwigshafen Germany
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BorsodChem Zrt. - OR, Bolyai ter 1. H-3700 Kazincbarcika Hungary
  • Brenntag Holding GmbH , Messeallee 11 45131 Essen Germany
  • Celanese Europe BV, The New Atrium Strawinskylaan 3105 1077 ZX Amsterdam Netherlands
  • Charles River Laboratories Den Bosch B.V. OR06, Hambakenwetering 7 5231DD 's-Hertogenbosch Netherlands
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Coty Services and Logistics GmbH, Berliner Allee 65 64295 Darmstadt Germany
  • Coty Services UK Ltd, Eureka Park TN25 4AQ Ashford Kent United Kingdom
  • Covestro Deutschland AG, Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany
  • DKSH Great Britain Ltd., 3 London Bridge Street 3rd Floor, News Building SE1 9SG London United Kingdom
  • Donauchem GmbH, Lisztstraße 4 1037 Vienna Vienna Austria
  • DOW BENELUX B.V. OR-10, Postbus 48 4530 AA Terneuzen Netherlands
  • DSM Coating Resins B.V., Ceintuurbaan 5 8022 AW Zwolle Netherlands
  • East-West Chemicals Asset Management Limited, Stasinou 1 1505 Nicosia Cyprus
  • Eckart GmbH, Guentersthal 4 D-91235 Hartenstein Bavaria Germany
  • ELC Group s.r.o., Karolinská 650/1 186 00 Prague 8 Czech Republic
  • ELGA EUROPE SRL, Via della Merlata, 8 20014 NERVIANO MILANO Italy
  • Ercros SA, Avenida Diagonal 593-595 08014 Barcelona Spain
  • ERNESTO VENTOS, S.A., Carretera Reial 120B 08960 Sant Just Desvern Spain
  • Godavari Biorefineries B.V, Wilhelminastraat 43A, 2011 VK, Haarlem - The Netherlands. 2011 VK Haarlem Netherlands
  • Helm AG, Nordkanalstraße 28 20097 Hamburg Germany
  • Henkel Belgium Operations N.V., Havenlaan 16 1080 Brussels Belgium
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Hungary Musashi Paint Kft., Bokodi u. 11 2840 Oroszlany Hungary
  • Ineos Manufacturing (Hull) Ltd - (Oxide), Saltend Hedon HU12 8DS Hull United Kingdom
  • INEOS nv, Haven 1053 -- Nieuwe Weg 1 2070 Zwijndrecht Belgium
  • Integrated DNA Technologies BVBA, Interleuvenlaan 12 A 3001 Leuven Belgium
  • Intertek Deutschland GmbH DSM, Stangenstrasse 1 70711 Leinfelden-Echterdingen Baden-Württemberg Germany
  • Isochem Kautschuk Gesellschaft mbH, Staatsrat-Schwamb-Str. 144 55278 Undenheim Rheinland-Pfalz Germany
  • ITW Performance Polymers, A Division of ITW Ireland, Bay 150 Shannon Industrial Estate V14 DF82 Shannon Co. Clare Ireland
  • Jubilant Lifesciences NV, Axxes Business Park - Guldensporenpark 22 - block C 9820 Merelbeke Belgium
  • KCC Europe GmbH, Hansaring 61 50670 Köln Germany
  • knoell Germany – OR – A1, Konrad-Zuse-Ring 25 68163 Mannheim Germany
  • Lonza Cologne GmbH, Nattermannallee 1 50829 Cologne Germany
  • LORD Germany GMBH, Ottostrasse 28 41836 Hueckelhoven North Rhine - Westphalia Germany
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Lubrizol Europe Coordination Center BVBA 02 , Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 30, Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Limited, The Knowle, Nether Lane Hazelwwod DE56 4AN Derby Derbyshire United Kingdom
  • MHM Holding GmbH, Feldkirchener Straße 15 D-85551 Kirchheim Germany
  • Momentive Performance Materials GmbH, Chempark Building V7 51368 Leverkusen NRW Germany
  • Nouryon Chemicals SPA, Localita Colafona 3/A Cavanella Po 45011 Adria Rovigo Italy
  • Panasonic Industrial Devices Slovakia s.r.o., Oravicka 616 02801 Trstena Slovakia
  • Penn Color International BV, Smakterweg 31 5804 AE Venray Netherlands
  • PPG Europe B.V. in its legal capacity as Only Representative of PRC DeSoto International Inc. - OR5, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Industries Italia Srl Società soggetta a direzione e coordinamento da parte di PPG Industries Inc., Via Serra, 1 15028 Quattordio Italy
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford, Dublin 18, Ireland Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • RECHIM Srl, Via Argentana, 4 44048 Traghetto FERRARA Italy
  • RHODIA OPERATIONS - 1, 40 rue de la Haie Coq 93306 Aubervilliers France
  • Sakata Inx España,S.A., C/ Mercaders 24-26. Pol.Ind.Riera de Caldes E-08184 Palau-Solità i Plegamans Barcelona Spain
  • SAPICI SpA, via Porlezza 16 20123 Milano MI Italy
  • Sasol Chemie GmbH & Co. KG, Anckelmannsplatz 1 20537 Hamburg Germany
  • SEKAB Biofuels & Chemicals, Box286 89126 Örnsköldsvik Sweden
  • SHOWA DENKO EUROPE GmbH, KONRAD-ZUSE-PLATZ 3 81829 München Germany
  • Sigma-Aldrich Biochemie GmbH, Georg-Heyken-Str. 14 21147 Hamburg Germany
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • SIGMA-ALDRICH CHIMIE SARL, 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France
  • Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom
  • Sigma-Aldrich Ireland Ltd, Vale Road . Arklow Co. Wicklow Ireland
  • Sigma-Aldrich Sweden AB, Solkraftsvägen 14C S-135 70 Stockholm Sweden
  • Silberline Ltd, Banbeath Road KY8 5HD Leven Fife United Kingdom
  • SITITALIA S.p.A., Via Pierini, 14-16 61122 Pesaro (PU) Italy
  • Solutia Europe SPRL/BVBA, Corporate Village - Aramis Building Leonardo Da Vincilaan 1 1930 Zaventem Belgium
  • Specialty Electronic Materials Belgium, BVBA OR-1, Sneeuwbeslaan 20 / Pb10 B-2610 Wilrijk Belgium
  • Sun Chemical B.V., Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands
  • Sun Chemical Nyomdafesték Kereskedelmi ès Gyarto KFT, Telek u. 7-9 H-1152 Budapest Hungary
  • Sustainability Support Services (Europe) AB, Markaskälsvägen 6 22647 Lund Sweden
  • Südpack Verpackungen GmbH & Co.KG, Postfach 1264 88412 OCHSENHAUSEN Germany
  • Tetra Tech International, Fuchsstrasse 1 67688 Rodenbach Germany
  • TEVA Pharmaceutical Works Private Ltd. Co., Pallagi str. 13 H-4042 Debrecen Hungary
  • The Acta Group EU BVBA (BE38), Place du Luxembourg 2 1050 Brussels Belgium
  • TOKUYAMA EUROPE GMBH, Berliner Allee 38 40212 Düsseldorf Germany
  • TOYO INK EUROPE SPECIALTY CHEMICALS, Boulevard Dambourney BP4 76350 Oissel France
  • Toyota Tsusho Europe S.A., Belgicastraat 13 1930 Zaventem Belgium
  • UAB "APLINKOS VADYBA", Vilkpėdės g. 22 03151 Vilnius Lithuania
  • Yakult Europe B.V., Schutsluisweg 1 1332 EN ALMERE Netherlands
  • Yordas GmbH, Äußere Nürnberger Str. 62, 91301 Forchheim Germany
  • Arcerion GmbH, Gabrielenstr. 15 80636 Muenchen Germany
  • Bax Chemicals BV, Essebaan 65 2908 LJ Capelle a.d. IJssel Netherlands Netherlands
  • Bestseller A/S, Moltrup Landevej 201 6100 Haderslev Denmark
  • Celanese Chemicals Ibérica, S.L., Carretera Nacional 340, Km. 1155 Polígono Industrial TAQSA E-43.206 Reus (Tarragona) Spain
  • COBELSA COSMETICOS, S.A., Poligono Industrial Banuelos Ctra. Alcala a Daganzo Km 3,870 -Alcala de Henares 28806 MADRID Spain
  • Henkel AG & Co. KGaA, Henkelstrasse 67 40191 Duesseldorf North-Rhine Westfalia Germany
  • Henkel Balti Ösauhing, Riia 128 51013 Tartu Estonia
  • Henkel Italia Operations S.r.L., Via Amoretti 78 20157 Mailand Italy
  • HML Europe BV, De Haal 82 1511 AT Oostzaan Netherlands
  • Honeywell Specialty Chemicals Seelze GmbH, Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • PRODUCTOS CAPILARES L'OREAL S.A., Calle Josefa Valcarcel num. 48 28027 MADRID Spain
  • RHODIA OPERATIONS, 40 rue de la Haie Coq 93306 AUBERVILLIERS France

Other names

  • -
  • 1-acetoxyethane
  • Acetato di Etile
  • Acetic acid ethyl ester
  • Acetic acid ethylester
  • Acetic acid, ethyl ester
  • Acetic acid, ethylester
  • acide ethanoique
  • ehtyl acetate
  • Essigsäureethylester
  • Etac
  • ETANOATO DI ETILE
  • Ethy Acetate
  • Ethyl aceate
  • Ethyl acetat
  • ETHYL ACETATE
  • Ethyl acetate / Ethyl ethanoate
  • Ethyl acetate.
  • Ethyl actetate
  • ETHYL ETHANOATE
  • Ethyl-acetate
  • ethyl.acetate
  • Ethylacetat
  • Ethylacetate
  • ethylacetát
  • Ethylethanoat
  • Etil-acetát
  • etyl acetate
  • etylacetat
  • Godavari Biorefineries B.V
  • Musashi
  • Reaction mass of calcium carbonate and Limestone and 2,2'-thiodiethanethiol and ammonium phosphinate and titanium dioxide and ferbam
  • Reaction mass of propane and butane and White mineral oil (petroleum) and 67-63-0 and 75-28-5
  • 037U
  • Ethyl Acetate
  • ethyl ethanoate
  • KP9960-BTX
  • KP9960-BTX(WD)
  • UP5403(C)-R
  • UP5403(KC)

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 8 studies submitted
  • 4 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [4]
C Form
Not specified (100%) [2]
C Odour
Other (67%), Sweetish (33%) [3]
C Substance type
Organic (100%) [4]

Type of Study provided
Studies with data
Key study 1 3
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 22 studies submitted
  • 5 studies processed
R Melting / freezing point
-83.6 - -83 °C @ 101.325 kPa [5]

Type of Study provided
Studies with data
Key study 3 2
Supporting study 5 12
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Melting / freezing point at 101 325 Pa
-84.15 - -83 °C

Boiling point

Study results
  • 19 studies submitted
  • 4 studies processed
R Boiling point
77 - 77.11 °C @ 101.325 kPa [4]

Type of Study provided
Studies with data
Key study 4
Supporting study 3 12
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Boiling point at 101 325 Pa
76.85 - 77.1 °C

Density

Study results
  • 22 studies submitted
  • 6 studies processed
R Bulk density
0.895 - 0.901 g/cm³ @ 20 - 25 °C [9]

Type of Study provided
Studies with data
Key study 6
Supporting study 4 12
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Relative density at 20°C
0.901 - 900.3

Vapour pressure

Study results
  • 23 studies submitted
  • 6 studies processed
R Vapour pressure
91.87 - 129.25 hPa @ 18.68 - 25.53 °C [10]

Type of Study provided
Studies with data
Key study 4 2
Supporting study 3 14
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Vapour pressure
10.3 - 11.3 kPa @ 20 - 21 °C

Partition coefficient

Study results
  • 13 studies submitted
  • 3 studies processed
R Log Pow
0.68 - 0.73 @ 20 - 25 °C and pH 7 [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 3 3 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Log Kow (Log Pow)
0.68 - 0.73 @ 20 - 25 °C

Water solubility

Study results
  • 23 studies submitted
  • 5 studies processed
R Water solubility (mass/vol.)
80 - 87.9 g/L @ 20.4 - 25.1 °C and pH 7 [6]

Type of Study provided
Studies with data
Key study 5
Supporting study 4 14
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Water solubility
80 - 83.1 g/L @ 20 - 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 17 studies submitted
  • 5 studies processed
R Flash point
-4.4 - -4 °C @ 101.325 kPa [5]

Type of Study provided
Studies with data
Key study 5
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Flash point at 101 325 Pa
-4.15 - -4 °C

Auto flammability

Study results
  • 10 studies submitted
  • 4 studies processed
R Autoflammability / self-ignition
426 - 427 °C @ 101.325 kPa [6]

Type of Study provided
Studies with data
Key study 2 2
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Autoflammability / self-ignition at 101 325 Pa
426 - 426.85 °C

Flammability

Study results
  • 11 studies submitted
  • 5 studies processed
C Interpretation of results
Highly flammable (100%) [5]

Type of Study provided
Studies with data
Key study 3 2
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Flammability
Highly flammable (100%)

Explosiveness

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 14 studies submitted
  • 2 studies processed
R dynamic viscosity (in mPa s)
0.451 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 4 8
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Dynamic viscosity at 20 °C
0.45 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 28 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 18 8 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 27 studies submitted
  • 4 studies processed
R BOD5
1.24 mg O2/g test material [1]
R COD
1.69 g O2/g test material [2]
C Interpretation of results
Readily biodegradable (100%) [4]

Type of Study provided
Studies with data
Key study 4
Supporting study 23
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2 2
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 240 µg/L (2)
Intermittent releases (freshwater) 1.65 mg/L (2)
Marine water 24 µg/L (2)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 650 mg/L (2)
Sediment (freshwater) 1.15 mg/kg sediment dw (2)
Sediment (marine water) 115 µg/kg sediment dw (2)
Hazard for Air
Air No hazard identified (2)
Hazard for Terrestrial Organism
Soil 148 µg/kg soil dw (2)
Hazard for Predators
Secondary poisoning 200 mg/kg food (2)

Short–term toxicity to fish

Study results
  • 22 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 230 mg/L [2]
EC50 (4 days) 220 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 20
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
LC50 for freshwater fish
230 mg/L

Long–term toxicity to fish

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
NOEC (32 days) 9.65 mg/L [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2 2
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC10 / LC10 or NOEC for freshwater fish
6.9 mg/L

Short–term toxicity to aquatic invertebrates

Study results
  • 30 studies submitted
  • 3 studies processed
P/RResults
IC50 (24 h) 346 - 655 mg/L [6]

Type of Study provided
Studies with data
Key study 1
Supporting study 25
Weight of evidence 4
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
EC50 / LC50 for freshwater invertebrates
165 - 3 090 mg/L
EC50 / LC50 for marine invertebrates
346 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 3 studies processed
P/RResults
NOEC (21 days) 2.4 mg/L [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
EC10 / LC10 or NOEC for freshwater invertebrates
2.4 mg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 16 studies submitted
  • 3 studies processed
P/RResults
EC50 (48 h) 5.6 g/L [1]
NOEC (72 h) 100 mg/L [2]
EC10 (48 h) 2.3 g/L [1]

Type of Study provided
Studies with data
Key study 3
Supporting study 13
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
EC50 for freshwater algae
5.6 g/L
EC10 or NOEC for freshwater algae
1 g/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 16 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 8
Weight of evidence 8
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC10 or NOEC for microorganisms
650 mg/L

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 734 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 1 468 mg/m³ irritation (respiratory tract)
Local Effects
Long-term: (DNEL) 734 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 1 468 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 63 mg/kg bw/day irritation (respiratory tract)
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 367 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 734 mg/m³ irritation (respiratory tract)
Local Effects
Long-term: (DNEL) 367 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 734 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 37 mg/kg bw/day irritation (respiratory tract)
Acute /short term: No hazard identified
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.5 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
Low hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 26 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 4
Supporting study 16 6
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study 2 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 16 studies submitted
  • 6 studies processed
P/RResults
LD50 11.3 mL/kg bw (rat) [3]
LD50 4 934 mg/kg bw (rabbit) [3]
M/CInterpretations of results
Not classified [6]

Type of Study provided
oral
Studies with data
Key study 2
Supporting study 10
Weight of evidence 4
Other
Data waiving
no waivers
inhalation
  • 20 studies submitted
  • 2 studies processed
P/RResults
LCLo (6 h) 6 000 ppm (rat) [2]
M/CInterpretations of results
Not classified [2]

inhalation
Studies with data
Key study 2
Supporting study 18
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 2 studies processed
P/RResults
LD50 20 000 mg/kg bw (rabbit) [2]
M/CInterpretations of results
Not classified [2]

dermal
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 10 200 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 2
Weight of evidence 4
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: eye
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 3
Supporting study 7
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 6 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 900 mg/kg bw/day [2]
LOAEL (rat): 3 600 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 14 studies submitted
  • 2 studies processed
P/RResults
NOEC (rat): 350 ppm [2]
LOEC (rat): 350 ppm [2]

Study data: inhalation
Studies with data
Key study 2
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 36 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 8 4
Supporting study 20
Weight of evidence 4
Other
Data waiving
no waivers
Study data: in vivo
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2 2
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 18 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2 2
Supporting study 10
Weight of evidence 4
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Study results
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 16
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant