Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Butyl acrylate
  • IUPAC name: butyl prop-2-enoate
  • Other names
EC / List no.:
205-480-7
CAS no.:
141-32-2
Index number:
607-062-00-3
Molecular formula:
C7H12O2
SMILES:
CCCCOC(=O)C=C
InChI:
InChI=1S/C7H12O2/c1-3-5-6-9-7(8)4-2/h4H,2-3,5-6H2,1H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
38
Of which contain:
5 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is a flammable liquid and vapour, causes serious eye irritation, causes skin irritation, may cause an allergic skin reaction and may cause respiratory irritation.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is harmful if inhaled and is harmful to aquatic life with long lasting effects.

Breakdown of all 2508 C&L notifications submitted to ECHA

Flam. Liq. 3 H226 Harmonised Classification
Skin Irrit. 2 H315 Harmonised Classification
Eye Irrit. 2 H319 Harmonised Classification
STOT SE 3 H335 Harmonised Classification
Acute Tox. 4 H332
Aquatic Chronic 3 H412
Skin Sens. 1B H317
Skin Sens. 1 H317 Harmonised Classification
Acute Tox. 4 H302
Acute Tox. 4 H312
Asp. Tox. 1 H304
Eye Irrit. 2A H319
Aquatic Chronic 2 H411
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss
  • PBT

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 144 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Substance included in the Community Rolling Action Plan (CoRAP).
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100 000 - 1 000 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: inks and toners, adhesives and sealants and coating products.

Other release to the environment of this substance is likely to occur from: indoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and of articles where the substances are not intended to be released and where the conditions of use do not promote release. Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper) and plastic (e.g. food packaging and storage, toys, mobile phones).

This substance is used in the following products: coating products, inks and toners, non-metal-surface treatment products, paper chemicals and dyes, polymers and washing & cleaning products.

This substance is used in the following areas: building & construction work and printing and recorded media reproduction. This substance is used for the manufacture of: plastic products, wood and wood products and furniture.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, mixing in open batch processes and non-industrial spraying.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: coating products, laboratory chemicals, inks and toners and polymers. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, laboratory work, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, manual maintenance (cleaning and repair) of machinery and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: polymers. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used for the manufacture of: chemicals and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers, mixing in open batch processes, closed processes with no likelihood of exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: for thermoplastic manufacture, as processing aid and as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers, closed processes with no likelihood of exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • 3M Deutschland GmbH, Carl-Schurz-Strasse 1 41453 Neuss Germany
  • 3M France SAS, 1 Parvis de l'Innovation CS 20203 95006 Cergy-Pontoise Cedex France
  • A.Schulman GmbH, Hüttenstrasse, 211 50170 Kerpen Germany
  • AAKO BV, Arnhemseweg 87 3832 GK Leusden Netherlands
  • Adhesives Research Ireland Limited, Raheen Business Park LK Limerick Limerick Ireland
  • AFCONA Additives B.V., Amperestraat 34 1704SN Heerhugowaard Netherlands
  • Allnex Belgium NV/SA OR1, Anderlechtstraat 33 1620 Drogenbos Belgium
  • ARKEMA B.V., headquarters Postbus 6030 3196 XH Vondelingenplaat Rotterdam Netherlands
  • ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
  • ARKEMA PHOTOCURES, 420 rue d'Estienne d'Orves 92700 Colombes France
  • ARKEMA S.R.L. Socio Unico, Via Pregnana 63 20017 Rho Milano Italy
  • Arpadis Benelux NV, Desguinlei 88A 2018 Antwerp Belgium
  • Ashland Services BV (0311), Noordweg 9 3336 LH Zwijndrecht Netherlands
  • Avery Dennison Materials Europe BV, Willem Einthovenstraat 11 2342 BH Oegstgeest Zuid-Holland Netherlands
  • Avestra Chemical Services Oy, Äyritie 12 A C/O F.I.N. Kontto Oy 01510 Vantaa Finland
  • Axalta Coating Systems Germany GmbH & Co. KG, Christbusch 25 42285 Wuppertal Germany
  • B-Lands Consulting (811603-7), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B.I.G. - OR18190, Technische Schoolstraat 43a 2440 Geel Belgium
  • B.I.G. - OR634, Technische Schoolstraat 43A 2440 Geel Belgium
  • B.I.G. - OR646, Technische Schoolstraat 43A 2440 Geel Belgium
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BCS Only Representative Services Ltd, Pembroke House 30 Upper Pembroke Street Dublin 2 Dublin Ireland
  • Bio4Life Holding BV, Venkelbaan 82 2908 KE Capelle aan den IJssel Netherlands
  • BorsodChem Zrt. - OR, Bolyai ter 1. H-3700 Kazincbarcika Hungary
  • Charles River Laboratories Den Bosch B.V. OR18, Hambakenwetering 7 5231 DD 's-Hertogenbosch Netherlands
  • ChemADVISOR Europe sprl (0509), Rue Joseph Stevens 7 Office 1409 B-1000 Brussels Belgium
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED (Jiangsu Sanmu Group Co., ltd.), Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemra GmbH, Max-Planck-Strasse 12 54296 Trier Germany
  • Chemservice S.A. (6HWD), 5, an de Laengten 6776 Grevenmacher Luxembourg
  • Chemservice S.A. (H5P7), 5, an de Laengten 6776 Grevenmacher Luxembourg
  • Chemservice S.A. (R9T3) , 5, an de Laengten 6776 Grevenmacher Luxembourg
  • Covestro Deutschland AG, Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany
  • CS Regulatory Ltd 2M, The Old Courthouse St Peters Churchyard DE1 1NN Derby Derbyshire United Kingdom
  • CS Regulatory Ltd 4M, The Old Courthouse St Peters Churchyard DE1 1NN Derby Derbyshire United Kingdom
  • DKSH Italia S.r.l., Via Salvatore Rosa, 14 20156 Milano Italy
  • Dow Belgium B.V.B.A., Sneeuwbeslaan 20, bus 10 2610 Wilrijik Belgium Belgium
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-10, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-11, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-13, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-14, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-5, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-6, Postbus 48 NL-4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-7, Postbus 48 NL-4530 AA Terneuzen Netherlands
  • Dow Benelux B.V. OR-20, Postbus 48 4530 AA Terneuzen Netherlands
  • Dow Benelux B.V. OR-51, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-52, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-53, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW OLEFINVERBUND GMBH, Strasse B 13 D-06258 Schkopau Germany
  • Dow Silicones Belgium SPRL OR-2, PSRC - rue Jules Bordet Parc industriel C 7180 Seneffe Belgium
  • DSM Coating Resins B.V., Ceintuurbaan 5 8022 AW Zwolle Netherlands
  • Du Pont (U.K.) Limited, London Road 4th Floor, Kings Court SG1 2NG Stevenage Hertfordshire United Kingdom
  • Du Pont de Nemours (Deutschland) GmbH, Hugenottenallee 173-175 D-63263 Neu-Isenburg Hesse Germany
  • Dynamit Nobel GmbH Explosivstoff- und Systemtechnik, Kalkstrasse 218 51377 Leverkusen Germany
  • ECEM, Hogehilweg 18 1101CD Amsterdam Noord Holland Netherlands
  • ENVIGO CRS SAU 104, Centro Industrial Santiga - Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • ENVIGO CRS SAU 108, Centro Industrial Santiga - Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • ENVIGO CRS SAU 156, Centro Industrial Santiga - Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • ENVIGO CRS SAU 160, Centro Industrial Santiga- Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • Evonik Degussa GmbH, Rellinghauser Strasse 1 - 11 C-ES 45128 Essen North Rhine-Westfalia Germany
  • Evonik Resource Efficiency GmbH, Rellinghauser Strasse 1-11 45128 Essen Germany
  • Evonik Resource Efficiency GmbH – M02, Rellinghauser Straße 1-11 45128 Essen Nordrhein-Westfalen Germany
  • Exponent International, The Lenz Hornbeam Business Park HG2 8RE Harrogate North Yorkshire United Kingdom
  • Galata Chemicals GmbH, Chemiestrasse 22 68623 Lampertheim 06 Germany
  • Gantrade Europe Limited, Birch House Fairfield Avenue TW18 4AB Staines Upon Thames Middlesex United Kingdom
  • Gazprom Marketing & Trading France27, 68 avenue des Champs Elysées 75008 PARIS France
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • HH Compliance Ltd, Rubicon Centre C.I.T. Campus T12 Y275 Bishopstown Cork Ireland
  • INEOS Styrolution Europe GmbH, Mainzer Landstrasse 50 60325 Frankfurt am Main Germany
  • International Farg AB, Box 44 SE 424 22 Angered Sweden
  • Intertek Deutschland GmbH 1, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH 16, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH 2, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH CZWC, Stangenstr.1 70771 Leinfelden-Echterdingen Germany
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • Jindal Films Europe Virton sprl, Zoning Industriel de Latour 6761 VIRTON Belgium
  • Kao Chemicals Europe, S.L. (2), Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain
  • knoell Germany - OR - B4, Konrad-Zuse-Ring 25 68163 Mannheim Germany
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • LG Chem Europe GmbH, Lyoner str 15, Atricom C6, D-60528 Frankfurt am Main Germany
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Lubrizol Deutschland GmbH, Max-Planck-Strasse 6 27721 RITTERHUDE Germany
  • Lubrizol Europe Coordination Center BVBA 02 , Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 16, Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Limited, The Knowle, Nether Lane Hazelwwod DE56 4AN Derby Derbyshire United Kingdom
  • Nouryon Surface Chemistry AB, Stenunge Allé 3 - S-44485 Stenungsund - Sweden
  • OMNOVA Solutions SAS (OR of OMNOVA Solutions Inc), 14 avenue des Tropiques ZA de Courtaboeuf 2, Villejust 91955 Courtaboeuf Cedex France
  • Pioneer Solutions Europe BVBA, De Roskam 13 2970 Schilde Belgium
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR2, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR3, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Industries Italia Srl Società soggetta a direzione e coordinamento da parte di PPG Industries Inc., Via Serra, 1 15028 Quattordio Italy
  • PPG Kansai Automotive Finishes France SAS, Les Dix Muids 59583 Marly France
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACH24H CONSULTING GROUP, 306 The Capel Building, Mary's Abbey, Dublin 7, Ireland Dublin 7 Dublin Ireland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • Red Orchid Consulting Oy Ltd, Viherkallionkuja 3 I 59 02710 Espoo Finland
  • SABIC Innovative Plastics BV, Plasticslaan 1 4612 PX Bergen op Zoom Netherlands Netherlands
  • Sasol Chemie GmbH & Co. KG, Anckelmannsplatz 1 20537 Hamburg Germany
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • Showa Denko Europe GmbH OR1, Konrad-Zuse-Platz 3 D-81829 Munich Germany
  • Specialty Electronic Materials Netherlands B.V., Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • Stadex Nederland BV as OR for Shandong, Boxbergerweg 119 7431PM Diepenveen Netherlands
  • Stahl Europe B.V., Sluisweg 10 5145PE Waalwijk Noord Brabant Netherlands
  • Stewardship Chemicals 28, Green Lowe Farm, Shawclough Road Waterfoot BB4 9SA Rossendale Lancashire United Kingdom
  • Sustainable Adhesive Products BV, Venkelbaan 82 2908 KE Capelle aan den IJssel Netherlands
  • Synthomer (UK) Limited, Central Road, Templefields CM20 2BH Harlow Essex United Kingdom
  • Synthomer (UK) Limited, Central Road Templefields CM20 2BH Harlow Essex United Kingdom
  • Synthomer a.s., Tovární 2093 356 01 Sokolov Czech Republic
  • Synthomer S.A., Boulevard du Textile 1 B-7700 Mouscron Belgium
  • Synthomer Trading Limited, 45 Pall Mall SW1Y 5JG London United Kingdom
  • Tetra Tech International, Fuchsstrasse 1 67688 Rodenbach Rhineland Pfalz Germany
  • TSGE_7-3, Concordia House, St. James Business Park Grimbald Crag Court HG5 8QB Knaresborough North Yorkshire United Kingdom
  • TÜV SÜD Iberia S.A.U. (052), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • TÜV SÜD Iberia S.A.U. (053), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • TÜV SÜD Industrie Service GmbH, Westendstraße 199 80686 München Germany
  • UMCO GmbH, Georg-Wilhelm-Straße 187 21107 Hamburg Germany
  • Valspar b.v., Zuiveringweg 89 8243 PE Lelystad Netherlands
  • Xerox (Europe) Limited, Ballycoolin Business Park Blanchardstown Dublin 15 Dublin Ireland
  • Xerox Manufacturing (Nederland) BV, Maasheseweg 89-91 5804 AB Venray Limburg Netherlands
  • Zeon Europe GmbH, Hansaallee 249 40549 Düsseldorf Germany
  • Zeon Europe GmbH, Hansaallee 249 40549 Düsseldorf NRW Germany
  • [Confidential], [Confidential]
  • Baltic International Trading OU, 5 Ryavala 10143 Tallinn Estonia
  • Henkel Belgium Operations N.V., Havenlaan 16 1080 Brussels Belgium
  • Henkel Italia Operations S.r.L., Via Amoretti 78 20157 Mailand Italy
  • SABIC Innovative Plastics Espana ScpA, Ctra. Cartagena-Alhama de Murcia km. 13. La Aljorra 30390 Cartagena Spain Spain
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium

Other names

  • -
  • 141-32-2
  • 2-Propenoic acid, butyl ester
  • 2-Propenoic acid, n-butyl ester
  • 20435_141-32-2
  • ABU
  • Acrylic acid butyl ester; n-Butyl acrylate; Acrylic acid, n-butyl ester; 2-Propenoic acid, butyl ester; Butyl 2-propenoate; n-Butyl propenoate; Butylacrylate, inhibited; Butyl ester kyseliny akrylove; UN 2348
  • Butyl 2-propenoate
  • butyl acrilate
  • Butyl acryate
  • BUTYL ACRYLATE
  • butyl acrylate (BA)
  • Butyl Acrylate (stabilized with MEHQ)
  • Butyl prop-2-enoate
  • butyl propenoate
  • Butylacrylat
  • Butylacrylate
  • butyll prop-2-enoate
  • n Butyl acrylate monomer
  • n-Butyl Acrylate
  • n-Butylacrylate
  • Butyl acrylate
  • n-butyl acrylate
  • 2-Propenoic acid, butyl ester (9CI)
  • Acrylic acid butyl ester (6CI, 8CI)
  • Acrylic acid n-butyl ester
  • Acrylic acid n-butyl ester, Butyl 2-propeonate
  • ACRYLIC ACID NORMAL-BUTYL ESTER
  • Acrylic acid, butyl ester
  • Acrylsaeurebutylester
  • BA
  • Butyl 2-propenoate
  • Butyl Acrylate
  • Butyl Acrylate ; Acrylic acid butyl ester
  • Butyl Acylate
  • Butyl Acylate Monomer
  • Butyl ester acrylic acid
  • Butyl Propenoate
  • FLOWING AGENT TP88
  • n-butyl acetate
  • N-Butyl Acrylate
  • N-BUTYL-2-PROPENOATE
  • n-Butylacrylat
  • TP88
  • UN 2348
  • ZMATLTXT

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 1 study processed
R Melting / freezing point
-64.6 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-64.6 °C

Boiling point

Study results
  • 2 studies submitted
  • 1 study processed
R Boiling point
147 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
147 °C

Density

Study results
  • 3 studies submitted
  • 1 study processed
R Density
0.86 - 0.9 g/cm³ @ 20 - 60 °C [3]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
0.9

Vapour pressure

Study results
  • 3 studies submitted
  • 1 study processed
R Vapour pressure
5 hPa @ 22.2 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
5 hPa @ 22.2 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 1 study processed
R Log Pow
2.38 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
2.38 @ 25 °C

Water solubility

Study results
  • 4 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
1.7 g/L @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
1.7 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 4 studies submitted
  • 1 study processed
R Flash point
37 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
37 °C

Auto flammability

Study results
  • 4 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
275 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
275 °C

Flammability

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 3 studies submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
0.66 - 0.88 [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
0.88 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 2 studies submitted
  • 1 study processed
R Dissipation half life (DT50)
27.959 h [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 9 studies submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 8
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
21.9 Pa m³/mol @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Study results
  • 1 study submitted
  • 1 study processed
% Distribution in Media:
R Air 94.55 % [1]
R Water 5.24 % [1]
R Soil 0.1 % [1]
R Sediment 0.1 % [1]
R Suspended sediment 0 % [1]
R Biota 0 % [1]
R Aerosol 0 % [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 2.72 µg/L (1)
Intermittent releases (freshwater) 11 µg/L (1)
Marine water 272 ng/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 3.5 mg/L (1)
Sediment (freshwater) 33.8 µg/kg sediment dw (1)
Sediment (marine water) 3.38 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 1 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 12 studies submitted
  • 9 studies processed
P/RResults
LC50 (4 days) 1.1 - 56.2 mg/L [11]
LC0 (4 days) 890 - 46 400 µg/L [6]
LC100 (4 days) 3.32 - 68.1 mg/L [4]
NOEC (4 days) 381 - 3 800 µg/L [7]

Type of Study provided
Studies with data
Key study 9
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 8 studies submitted
  • 6 studies processed
P/RResults
EC50 (48 h) 1.3 - 19 mg/L [6]
LC50 (4 days) 1.6 mg/L [1]
EC0 (48 h) 700 - 12 500 µg/L [5]
LC0 (4 days) 990 µg/L [1]
EC100 (48 h) 2.8 - 50 mg/L [5]

Type of Study provided
Studies with data
Key study 6
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
NOEC (21 days) 136 - 457 µg/L [3]
LOEC (21 days) 450 - 1 226 µg/L [3]
EC50 (21 days) 500 µg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 8 studies submitted
  • 6 studies processed
P/RResults
EC50 (4 days) 2.65 - 11 mg/L [4]
EC50 (72 h) 1.71 - 14.6 mg/L [9]
NOEC (4 days) 1.8 - 3.8 mg/L [2]
NOEC (72 h) 450 - 3 850 µg/L [3]
LOEC (72 h) 900 - 7 700 µg/L [3]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 7 studies submitted
  • 2 studies processed
P/RResults
EC50 (30 min) 1 g/L [1]
EC0 (72 h) 150 mg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other 3
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (28 days) 1 g/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: Low hazard (no threshold derived)
Local Effects
Long-term: (DNEL) 11 mg/m³ irritation (respiratory tract)
Acute /short term: Medium hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: Medium hazard (no threshold derived)
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 3
Supporting study 7
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Oral: 100 %
Inhalation: 100 %

Acute toxicity

Study results
oral
  • 11 studies submitted
  • 1 study processed
P/RResults
LD50 3 150 mg/kg bw (rat) [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 9
Weight of evidence
Other 1
Data waiving
no waivers
inhalation
  • 20 studies submitted
  • 1 study processed
P/RResults
LC50 (4 h) 10 - 11.2 mg/L air (rat) [3]

inhalation
Studies with data
Key study 2
Supporting study 17
Weight of evidence
Other 1
Data waiving
no waivers
dermal
  • 8 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [1]

dermal
Studies with data
Key study 1
Supporting study 6
Weight of evidence
Other 1
Data waiving
no waivers
other routes
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 3 150 mg/kg bw
Inhalation route:
Adverse effect observed LC50 10 300 mg/m³
Dermal route:
Adverse effect observed Discriminating dose 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 15 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 9
Weight of evidence 4
Other 1
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 3 studies submitted
  • 1 study processed
P/RResults
NOAEL (rat): 84 - 111 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 3 studies submitted
  • 1 study processed
P/RResults
NOAEC (rat): 110 - 570 mg/m³ air [2]
LOAEC (rat): 570 - 1 110 mg/m³ air [2]

Study data: inhalation
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
No adverse effect observed NOAEL 84 mg/kg bw/day (subchronic, rat)
Inhalation route - systemic effects:
Adverse effect observed NOAEC 570 mg/m³ (subchronic, rat)
Inhalation route - local effects:
Adverse effect observed NOAEC 110 mg/m³ (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study
Supporting study 2
Weight of evidence 14
Other
Data waiving
no waivers
Study data: in vivo
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Dermal route:
No adverse effect observed NOAEL 8 mg/kg bw/day (chronic, mouse)
Inhalation route:
No adverse effect observed NOAEC 80 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 2 1
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study 2
Weight of evidence 3 1
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 150 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 286 mg/m³ (subchronic, rat)
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 400 mg/kg bw/day (subacute, rabbit)
Inhalation route:
Adverse effect observed NOAEC 133 mg/m³ (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant