Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Triethylamine
  • IUPAC name: triethylamine
  • Other names
EC / List no.:
204-469-4
CAS no.:
121-44-8
Index number:
612-004-00-5
Molecular formula:
C6H15N
SMILES:
CCN(CC)CC
InChI:
InChI=1S/C6H15N/c1-4-7(5-2)6-3/h4-6H2,1-3H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
10
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance causes severe skin burns and eye damage, is a highly flammable liquid and vapour, is harmful if swallowed, is harmful in contact with skin and is harmful if inhaled.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic in contact with skin, is toxic if inhaled, causes serious eye damage and may cause respiratory irritation.

Breakdown of all 5517 C&L notifications submitted to ECHA

Flam. Liq. 2 H225 Harmonised Classification
Acute Tox. 4 H302 Harmonised Classification
Skin Corr. 1A H314 Harmonised Classification
STOT SE 3 H335
Acute Tox. 3 H311
Acute Tox. 3 H331
Eye Dam. 1 H318
Acute Tox. 4 H332 Harmonised Classification
Acute Tox. 4 H312 Harmonised Classification
STOT SE 3 H336
Acute Tox. 3 H312
Not Classified
Acute Tox. 2 H330
Skin Corr. 1C H314
Met. Corr. 1 H290
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • PBT

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 26 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 10 000 - 100 000 tonnes per year.

This substance is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in products with material based on: leather (e.g. gloves, shoes, purses, furniture).

This substance is used in the following products: pH regulators and water treatment products, polymers, coating products, metal working fluids, paper chemicals and dyes, metal surface treatment products, lubricants and greases and plant protection products.

This substance is used for the manufacture of: chemicals, pulp, paper and paper products and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, non-industrial spraying, mixing in open batch processes, roller or brushing applications, treatment of articles by dipping and pouring, transfer of substance into small containers and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, in processing aids at industrial sites, in the production of articles and of substances in closed systems with minimal release. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: polymers, metal working fluids, pH regulators and water treatment products, lubricants and greases, coating products, laboratory chemicals, adhesives and sealants, metal surface treatment products and paper chemicals and dyes.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, transfer of substance into small containers, mixing in open batch processes, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials, manufacturing of the substance and in the production of articles.

This substance is used in the following products: pH regulators and water treatment products, polymers, metal working fluids, laboratory chemicals, paper chemicals and dyes, adhesives and sealants and lubricants and greases. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: mining. This substance is used for the manufacture of: chemicals, textile, leather or fur, rubber products, plastic products and fabricated metal products.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, transfer of chemicals, batch processing in synthesis or formulation with opportunity for exposure, industrial spraying, mixing in open batch processes, roller or brushing applications and treatment of articles by dipping and pouring.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), in the production of articles, as processing aid, as processing aid and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures and in processing aids at industrial sites.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
  • BASF Antwerpen N.V., Haven 725, Scheldelaan 600 2040 Antwerpen 4 Antwerpen Belgium
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, D02 Dublin Ireland
  • Chemours Netherlands B.V., Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • Chemra GmbH, Max-Planck-Strasse 12 54296 Trier Germany
  • Chemservice S.A - (H97P), 5, an de Laengten 6776 Grevenmacher Luxembourg
  • CS Regulatory Ltd 1L-26, The Old Courthouse St Peters Churchyard DE1 1NN Derby United Kingdom
  • DOW AGROSCIENCES B.V. (BE), Sneeuwbeslaan 20 – bus 10 2610 Wilrijk Belgium
  • DOW AGROSCIENCES LIMITED, CPC2 Capital Park, Fulbourn Cambridge CB21 5XE Cambridgeshire United Kingdom
  • DOW AGROSCIENCES S.A.S., 6 rue Jean-Pierre Timbaud, Immeuble Le Campus, Bâtiment.A 78180 Montigny-le-Bretonneux France
  • DOW ITALIA S.R.L., Via F. Albani 65 20148 Milano Italy
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • ITS Testing Services (UK) Ltd 4, Caleb Brett House 734 London Road RM20 3NL West Thurrock, Grays Essex United Kingdom
  • Life Technologies Europe BV, Kwartsweg 2 2665 NN Bleiswijk Netherlands
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Merck KGaA, Frankfurter Strasse 64293 Darmstadt Germany
  • momaja s.r.o., Karolinská 650/1 186-00 Prague 8 Czech Republic
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Industries Italia Srl Società soggetta a direzione e coordinamento da parte di PPG Industries Inc., Via Serra, 1 15028 Quattordio Italy
  • QUIMICA SINTETICA, S.A., C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • Sustainability Support Services (Europe) AB, Markaskälsvägen 6 22647 Lund Sweden
  • Taminco BVBA, Pantserschipstraat 207 9000 Gent Belgium
  • TFL ITALIA SpA, Via dei Campacci 11 20010 Buscate MI Italy

Other names

  • -
  • 121-44-8
  • Ethanamine,N,N-diethl
  • Ethanamine,N,N-diethyl
  • N,N,N,triethylamine
  • N,N-Diethylethanamine
  • TEA
  • TRIETHYL AMINE
  • Triethylamin
  • TRIETHYLAMINE
  • (Diethylamino)ethane
  • ethanamine, N,N-diethyl-
  • Ethanamine, N,N-diethyl- (9CI)
  • MISSION MODELS POLYURETHANE MIX ADDITIVE
  • N,N-Diethylethanamine
  • TEA
  • Triethylamin
  • TRIETHYLAMINE
  • Triethylamine (7CI, 8CI)

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Form
Not specified (100%) [2]
C Odour
Other (100%) [2]
C Substance type
Organic (100%) [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 1 study processed
R Melting / freezing point
-115 - -114.7 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
-115 °C

Boiling point

Study results
  • 5 studies submitted
  • 3 studies processed
R Boiling point
88 - 90 °C @ 101.3 kPa [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other 2
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Boiling point at 101 325 Pa
88.8 - 90 °C

Density

Study results
  • 3 studies submitted
  • 2 studies processed
R Density
0.73 g/cm³ @ 20 °C [1]
R Relative density
0.7 [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
0.73

Vapour pressure

Study results
  • 7 studies submitted
  • 1 study processed
R Vapour pressure
72 hPa @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Vapour pressure
68.99 - 72 hPa @ 20 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
1.45 @ pH 13 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 8 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
39.3 - 112.4 g/L @ 20 - 30 °C [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 7
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Water solubility
112 - 112.4 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Surface tension

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 5 studies submitted
  • 1 study processed
R Flash point
-11 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence 1
Other 1
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flash point at 101 325 Pa
-14.99 - -11 °C

Auto flammability

Study results
  • 3 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
215 °C [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 3 studies submitted
  • 2 studies processed
C Interpretation of results
Flammable (50%), Highly flammable (50%) [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1 1
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 5 studies submitted
  • 2 studies processed
C Interpretation of results
Non-explosive (100%) [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2 1
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers

No summary exists for this scientific endpoint

Dissociation constant

Study results
  • 5 studies submitted
  • 4 studies processed
C Dissociating properties
Yes (50%), Not determined (50%) [4]
R Dissociation constant
10.15 - 11.43 @ 0 - 35 °C [6]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2 1 2
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
0.363 [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1 3
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
4.5 h
Degradation rate constant with OH radicals
7.997 m³ molecule-1 d-1

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 12 studies submitted
  • 3 studies processed
C Interpretation of results
Readily biodegradable (67%), Under test conditions no biodegradation observed (33%) [3]

Type of Study provided
Studies with data
Key study 1
Supporting study 4
Weight of evidence 2
Other 3 2
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - L/kg ww
0.5 L/kg ww

Bioaccumulation: terrestrial

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
107.2

Henrys law constant (H)

Study results
  • 3 studies submitted
  • 3 studies processed
R H - (pressure) m³/mol
1.317 - 15.097 Pa m³/mol @ 25 °C [3]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
8.65 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1 2
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 110 µg/L (1)
Intermittent releases (freshwater) 80 µg/L (1)
Marine water 11 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 100 mg/L (1)
Sediment (freshwater) 1.575 mg/kg sediment dw (1)
Sediment (marine water) 158 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 250 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 7 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 24 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 5
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
24 mg/L

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
LOEC (60 days) 3.2 - 100 mg/L [3]
EC50 (60 days) 130 mg/L [1]
LC50 (60 days) 137 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
LC50 (48 h) 17 mg/L [1]
NOEC (48 h) 12 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 3
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
NOEC (21 days) 11 mg/L [1]
EC50 (21 days) 38 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
11 mg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 6.8 - 8 mg/L [2]
NOEC (72 h) 1.1 - 1.8 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
8 mg/L
EC10 or NOEC for freshwater algae
1.1 mg/L

Toxicity to aquatic plants other than algae

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (17 h) 95 - 1 000 mg/L [2]
EC10 (17 h) 71 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
1 g/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 12.1 mg/kg bw/day repeated dose toxicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
-
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
-

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 14 studies submitted
  • 1 study processed
P/RResults
LD50 730 mg/kg bw (rat) [1]
M/CInterpretations of results
Moderately toxic [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other 7 1
Data waiving
no waivers
inhalation
  • 20 studies submitted
  • 1 study processed
P/RResults
LC50 (60 min) 3 496 ppm (rat) [1]
M/CInterpretations of results
Other [1]

inhalation
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other 14 1 1
Data waiving
no waivers
dermal
  • 4 studies submitted
  • 1 study processed
P/RResults
LD50 580 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Highly toxic [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
other routes
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 15 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 12
Data waiving
no waivers
Study data: eye
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 6
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (corrosive)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Repeated dose toxicity

Study results
Study data: oral
  • 7 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study
Weight of evidence
Other 6
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: inhalation
  • 10 studies submitted
  • 1 study processed
P/RResults
NOAEC (rat): 103.3 - 1 020 mg/m³ air [2]
LOAEC (rat): 1.02 mg/L air [1]

Study data: inhalation
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 8
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other 1
Data waiving
no waivers
Study data: in vivo
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to reproduction

Study results
Study data: reproduction
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: developmental
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant