Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Allyl alcohol
  • IUPAC name: prop-2-en-1-ol
  • Other names
EC / List no.:
203-470-7
CAS no.:
107-18-6
Index number:
603-015-00-6
Molecular formula:
C3H6O
SMILES:
OCC=C
InChI:
InChI=1S/C3H6O/c1-2-3-4/h2,4H,1,3H2
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
16
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is toxic if swallowed, is toxic in contact with skin, is toxic if inhaled, is very toxic to aquatic life, is a highly flammable liquid and vapour, causes serious eye irritation, causes skin irritation and may cause respiratory irritation.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is fatal in contact with skin, is fatal if inhaled, is harmful to aquatic life with long lasting effects and is suspected of damaging fertility or the unborn child.

Breakdown of all 2432 C&L notifications submitted to ECHA

Acute Tox. 3 H301 Harmonised Classification
Aquatic Acute 1 H400 Harmonised Classification
Skin Irrit. 2 H315 Harmonised Classification
STOT SE 3 H335 Harmonised Classification
Flam. Liq. 2 H225 Harmonised Classification
Acute Tox. 2 H310
Aquatic Chronic 3 H412
Acute Tox. 2 H330
Eye Irrit. 2A H319
Eye Irrit. 2 H319 Harmonised Classification
Acute Tox. 3 H331 Harmonised Classification
Acute Tox. 3 H311 Harmonised Classification
Acute Tox. 1 H330
Repr. 2 H361
Flam. Liq. 3 H226
https://echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 22 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 10 000 - 100 000 tonnes per year.

This substance is used in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, transfer of substance into small containers, laboratory work, closed processes with no likelihood of exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, in processing aids at industrial sites and as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, transfer of substance into small containers, closed processes with no likelihood of exposure, laboratory work, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites, as processing aid, for thermoplastic manufacture and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, transfer of substance into small containers, production of mixtures or articles by tabletting, compression, extrusion or pelletisation and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, in processing aids at industrial sites and as an intermediate step in further manufacturing of another substance (use of intermediates).

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If on skin (or hair): follow instructions specified by manufacturer/supplier. If in eyes: follow instructions specified by manufacturer/supplier.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Aceto France, 43 avenue marceau 75116 Paris France
  • ACOMON S.R.L., VIA BAIONA, 107 48100 RAVENNA ITALY Italy
  • ACS DOBFAR S.p.A, Viale Addetta 4/12 20067 Tribiano Milano Italy
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • CCD (Germany) GmbH, Graf-Adolf-Strasse 68 40210 Düsseldorf Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHT Germany GmbH, Bismarckstr. 102 72072 Tuebingen Germany
  • DOW BENELUX B.V. - OR1, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-3, Postbus 48 4530 AA Terneuzen Netherlands
  • Dow Silicones Belgium SPRL OR-1, PSRC - rue Jules Bordet Parc industriel C 7180 Seneffe Belgium
  • Dow Silicones Belgium SPRL OR-2, PSRC - rue Jules Bordet Parc industriel C 7180 Seneffe Belgium
  • Elementis UK Ltd., Caroline House 55 - 57 High Holborn WC1V 6DX London United Kingdom
  • Evonik Nutrition & Care GmbH, Rellinghauser Strasse 1-11 45128 Essen Germany
  • Evonik Nutrition & Care GmbH - OR2, Goldschmidtstrasse 100 45127 Essen Germany
  • knoell Germany - OR - B19, Konrad-Zuse-Ring 25 68163 Mannheim Germany
  • knoell Germany – OR – B10, Konrad-Zuse-Ring 25 68163 Mannheim Germany
  • LCNBV-OR-CXV, Delftseplein 27E 3013 AA Rotterdam Netherlands
  • Lyondell Chemie Nederland B.V., Deltseplein 27E 3013 AA Rotterdam Netherlands
  • Momentive Performance Materials GmbH, Chempark Building V7 51368 Leverkusen NRW Germany
  • SHOWA DENKO EUROPE GmbH, KONRAD-ZUSE-PLATZ 3 81829 München Germany
  • SUEZ Water Technologies & Solutions Belgium BVBA, Toekomstlaan 54 2200 Herentals Belgium
  • SUEZ WTS France, Tour CB21 16 Place de l’Iris 92040 Paris La Défense France

Other names

  • -
  • 2-Propen-1-ol
  • Allyl Alcohol
  • allyl-alcohol-
  • Allylalcohol
  • Allylalkohol
  • prop-2-en-1-ol
  • ALLYL ALCOHOL
  • ALLYLIC ALCOHOL

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 4 studies submitted
  • 3 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [3]
C Form
Other (100%) [1]
C Odour
Other (100%) [2]
C Substance type
Organic (100%) [3]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 2 studies processed
R Melting / freezing point
-129 °C [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-129 °C

Boiling point

Study results
  • 9 studies submitted
  • 9 studies processed
R Boiling point
94 - 98 °C @ 101.3 kPa [9]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 7 2
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Boiling point at 101 325 Pa
97 - 97.4 °C

Density

Study results
  • 8 studies submitted
  • 8 studies processed
R Density
0.847 - 0.854 g/cm³ @ 19.85 - 25 °C [4]
R Relative density
0.85 - 0.9 @ 20 °C [4]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 6 2
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Relative density at 20°C
0.854

Vapour pressure

Study results
  • 8 studies submitted
  • 7 studies processed
R Vapour pressure
13.332 - 100 hPa @ 10 - 44.5 °C [8]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 6 1 1
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Vapour pressure
31.4 - 100 hPa @ 25 - 44.5 °C

Partition coefficient

Study results
  • 5 studies submitted
  • 4 studies processed
R Log Pow
0.17 @ 25 °C [4]

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 1 3
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Log Kow (Log Pow)
0.17 @ 25 °C

Water solubility

Study results
  • 8 studies submitted
  • 3 studies processed
R Water solubility (mass/vol.)
4.3 - 1 000 g/L @ 20 - 25 °C [4]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence 3 2
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Water solubility
4.3 - 1 000 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 1 study processed
R Surface tension
73.1 mN/m @ 1 g/L and 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
73.1 mN/m @ 1 000 mg/L

Flash point

Study results
  • 7 studies submitted
  • 7 studies processed
R Flash point
21 - 32.222 °C @ 101.3 kPa [11]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 5 2
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flash point at 101 325 Pa
21 °C

Auto flammability

Study results
  • 6 studies submitted
  • 6 studies processed
R Autoflammability / self-ignition
348 - 443 °C [7]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 4 2
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
Autoflammability / self-ignition at 101 325 Pa
375 - 378 °C

Flammability

Study results
  • 4 studies submitted
  • 2 studies processed
C Interpretation of results
Flammable (100%) [2]

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 2 studies processed
C Dissociating properties
Yes (100%) [2]
R Dissociation constant
15.5 @ 25 °C [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
pKa at 20 °C
15.5

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
10 [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
10 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 4 studies submitted
  • 4 studies processed
C Interpretation of results
Readily biodegradable (100%) [4]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 2 1
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 3.2 µg/L (1)
Intermittent releases (freshwater) 3.2 µg/L (1)
Marine water 320 ng/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 10 mg/L (1)
Sediment (freshwater) 12.7 µg/kg sediment dw (1)
Sediment (marine water) 1.27 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 3.68 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning 330 µg/kg food (1)

Short–term toxicity to fish

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 320 - 589 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
320 µg/L

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 1.65 - 2.05 mg/L [2]
EC50 (24 h) 3.66 mg/L [1]
NOEC (48 h) 1.06 mg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
1.65 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
NOEC (21 days) 919 µg/L [1]
LOEC (21 days) 919 µg/L [1]
EC50 (21 days) 919 µg/L [1]
LC50 (21 days) 1.36 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
919 µg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 3 studies submitted
  • 3 studies processed
P/RResults
EC50 (72 h) 2.25 - 9.69 mg/L [6]
EC50 (48 h) 9.69 mg/L [1]
NOEC (72 h) 930 - 9 690 µg/L [5]
NOEC (48 h) 9.69 mg/L [1]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
5.38 mg/L
EC10 or NOEC for freshwater algae
930 µg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
IC50 (48 h) 82.755 mmol/L [1]
NOEC (14 days) 100 mg/L [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
100 mg/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.63 mg/m³ repeated dose toxicity
Acute /short term: - -
Local Effects
Long-term: No hazard identified
Acute /short term: (DNEL) 12.1 mg/m³ acute toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 125 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 7.6 mg/kg bw/day acute toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 75 µg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study 4 3
Weight of evidence
Other 1
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
Low bioaccumulation potential

Acute toxicity

Study results
oral
  • 6 studies submitted
  • 4 studies processed
P/RResults
LD50 64 - 105 mg/kg bw (rat) [5]
LD50 72 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Category 3 based on GHS criteria [3]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 2
Weight of evidence 3
Other
Data waiving
no waivers
inhalation
  • 3 studies submitted
  • 1 study processed
P/RResults
LC50 (8 h) 50 ppm (rat) [1]
LC50 (4 h) 100 ppm (rat) [1]
LC50 (60 min) 400 ppm (rat) [1]

inhalation
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 89 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Toxicity Category II [1]

dermal
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 64 mg/kg bw
Inhalation route:
Adverse effect observed LC50 300 mg/m³
Dermal route:
Adverse effect observed LD50 89 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 1
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: eye
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 2 1
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence 4
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 4 studies submitted
  • 3 studies processed
P/RResults
NOAEL (rat): 0.05 - 3 mg/kg bw/day [2]
NOAEL (mouse): 6 mg/kg bw/day [1]
LOAEL (rat): 0.5 - 6 mg/kg bw/day [2]
LOAEL (mouse): 12 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 2 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
LOAEL (rat): 40 ppm [1]
NOAEC (rat): 20 ppm [1]

Study data: inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 4 1
Supporting study 4
Weight of evidence 3
Other
Data waiving
no waivers
Study data: in vivo
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 5
Supporting study 1
Weight of evidence 2
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant