Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Buta-1,3-diene
  • IUPAC name: buta-1,3-diene
  • Other names
EC / List no.:
203-450-8
CAS no.:
106-99-0
Index number:
601-013-00-X
Molecular formula:
C4H6
SMILES:
C=CC=C
InChI:
InChI=1S/C4H6/c1-3-4-2/h3-4H,1-2H2
Type of substance:
Mono constituent substance
Origin:
Petroleum product
Registered compositions:
42
Of which contain:
7 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance may cause genetic defects, may cause cancer and is an extremely flammable gas.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is suspected of damaging fertility or the unborn child and is harmful to aquatic life with long lasting effects.

Breakdown of all 1188 C&L notifications submitted to ECHA

Carc. 1A H350 Harmonised Classification
Muta. 1B H340 Harmonised Classification
Flam. Gas 1 H220 Harmonised Classification
Repr. 2 H361
Aquatic Chronic 3 H412
Press. Gas (Comp.) H280
Not Classified
Muta. 1A H340
STOT SE 3 H336
Press. Gas Harmonised Classification
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • C
  • M
  • PBT

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 209 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Substance included in the Community Rolling Action Plan (CoRAP).
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000 000 - 10 000 000 tonnes per year.

This substance is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation, the low energy manipulation of substances bound in materials or articles and high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding).

Release to the environment of this substance can occur from industrial use: formulation in materials, in processing aids at industrial sites, for thermoplastic manufacture, manufacturing of the substance, formulation of mixtures, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, as processing aid and of substances in closed systems with minimal release.

This substance can be found in complex articles, with no release intended: vehicles. This substance can be found in products with material based on: rubber (e.g. tyres, shoes, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).

This substance is used in the following products: polymers.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, the low energy manipulation of substances bound in materials or articles and calendering operations.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.

This substance is used in the following products: fuels and polymers.

This substance is used in the following activities or processes at workplace: transfer of chemicals, laboratory work, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, transfer of substance into small containers, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, in processing aids at industrial sites, formulation in materials, manufacturing of the substance, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance is used in the following products: polymers, extraction agents and fuels.

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, calendering operations, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as processing aid, for thermoplastic manufacture, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release, formulation of mixtures, manufacturing of the substance and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, laboratory work, batch processing in synthesis or formulation with opportunity for exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, formulation of mixtures, formulation in materials, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use personal protective equipment as required..

Response statements

In case of incident: In case of leakage eliminate all ignition sources. In case of leaking gas fire do not extinguish unless leak can be stopped safely.

Storage statements

Store this substance protected from sunlight and in a well-ventilated place.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • 3M France SAS, Bld de l'oise 95006 Cergy-Pontoise France
  • Anthesis (Ireland) Limited 19, The Black Church St. Mary’s Place D07 P4AX Dublin Ireland
  • ARLANXEO Brasil S.A., Chempark 51369 Leverkusen NRW Germany
  • ARLANXEO Deutschland GmbH, Alte Heerstraße 2 41540 Dormagen Germany
  • ARLANXEO Singapore Pte. Ltd., Kaiser Wilhelm Allee 40 51369 Leverkusen NRW Germany
  • Axalta Coating Systems Germany GmbH & Co. KG, Christbusch 25 42285 Wuppertal Germany
  • B.I.G. - OR633, Technische schoolstraat 43 2440 Geel Belgium
  • B.I.G. - OR634, Technische Schoolstraat 43A 2440 Geel Belgium
  • B.I.G. - OR646, Technische Schoolstraat 43A 2440 Geel Belgium
  • B.I.G. - OR696, Technische Schoolstraat 43a 2440 Geel Belgium
  • Basell Polyolefine Gmbh, Bruhler strasse 60 D-50389 Wesseling Germany
  • Basell Polyoléfines France SAS, Chemin Departemental 21 A 13130 Berre l'Etang France
  • BASF Agricultural Specialities S.A.S., Z.I.En Jacca 10 Chemin de la Plaine 31770 Colomiers Toulouse France
  • BASF Antwerpen N.V., Haven 725, Scheldelaan 600 2040 Antwerpen 4 Antwerpen Belgium
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Borealis AG, Wagramerstrasse 17-19 1220 Wien Austria
  • Borealis Polymers Oy, P.O. Box 330 06101 Porvoo Finland
  • Bostik Nederland B.V., Zeggeveld #10 RP4705 Roosendaal Netherlands
  • Braskem Netherlands B.V., Weena 00240, C 9th floor NL - 3012 NJ PO Box 30128 3001 DC Rotterdam Netherlands
  • BSM-OR-polymers-Equistar, Delftseplein 27E 3013 AA Rotterdam Netherlands
  • BTC Europe GmbH, Rheinpromenade 1 40789 Monheim Germany
  • BUTACHIMIE, Immeuble Le Forum 29 RUE MAURICE FLANDIN 69003 LYON France
  • Butadien Kralupy a.s., O.Wichterleho 810 27801 Kralupy nad Vltavou Czech Republic
  • C.S.B. GmbH, Düsseldorfer Str. 113 47809 Krefeld Germany
  • C.S.B. GmbH, Duesseldorfer Str.113 47809 Krefeld Germany
  • C.S.B. GmbH 0239, Düsseldorfer Str. 113 47809 Krefeld Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, D02 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMIJOS INDUSTRIJA UAB, Birutes str. 16a LT-91210 Klaipėda Lithuania
  • Chemsafe Srl on behalf of Tabriz Petrochemical Company (T.P.C.), Via Ribes 5 10010 Colleretto Giacosa TO Italy
  • Chemservice GmbH - (8TV2), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice GmbH - (P9S8), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice S.A. (H5P7), 5, an de Laengten 6776 Grevenmacher Luxembourg
  • Chevron Phillips Chemicals International N.V. - OR SPC, Airport Plaza, Stockholm Bulding Da Vincilaan 19 B - 1831 DIEGEM Belgium
  • Chevron Phillips Chemicals International NV, Airport Plaza, Stockholm Building, Da Vincilaan 19 B-1831 DIEGEM Belgium
  • China System s.r.l. (OR), via Dei Volsci 163 00185 Rome Italy
  • CNP Polymer GmbH, schultessdamm 58 22391 hamburg hamburg Germany
  • ColorMatrix Europe Ltd, Units 7-15 Unity Grove L34 9GT Knowsley United Kingdom
  • Covestro Deutschland AG, Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany
  • CRAY VALLEY SA, 2 Place Jean Millier 92400 Courbevoie France
  • CRAY VALLEY SA OR8, 2 Place Jean Millier 92400 Courbevoie France
  • Cytec Engineered Materials GmbH in its legal capacity as OR of Cytec Industries Inc., Industriestraße 3 76684 Östringen Germany
  • Cytec Engineered Materials Ltd., Abenbury Way Wrexham Industrial Estate LL13 9UZ Wrexham United Kingdom
  • DDP Specialty Products Germany GmbH , August-Wolff-Strasse 13 29699 Bomlitz Germany
  • Denka Chemicals GmbH, Kaiserswerther Str. 183 40474 Dusseldorf Germany
  • Dow Belgium B.V.B.A., Sneeuwbeslaan 20, bus 10 2610 Wilrijik Belgium Belgium
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. - OR1, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. - OR2, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-7, Postbus 48 NL-4530 AA Terneuzen Netherlands
  • Dow Benelux B.V. OR-20, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-3, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW DEUTSCHLAND ANLAGENGESELLSCHAFT mbH, Am Kronberger Hang 4 D-65824 Schwalbach Germany
  • Dow France SAS, 23 Avenue Jules Rimet 93200 La Plaine Saint Denis France
  • DOW OLEFINVERBUND GMBH, Strasse B 13 D-06258 Schkopau Germany
  • Du Pont de Nemours (Deutschland) GmbH, Hugenottenallee 173-175 D-63263 Neu-Isenburg Hesse Germany
  • DYNASOL ELASTOMEROS OR, Calle Mendez Alvaro, 44 28045 MADRID Spain
  • Dynasol Elastómeros S.A., Carretera a Pedreña 39792 Gajano Cantabria Spain
  • Elastomer Trading Limited, 3 Pugh Place SS17 8BL Stanford-le-Hope Essex United Kingdom
  • Envigo Consulting Limited, Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom
  • ENVIGO CRS SAU 027, Centro Industrial Santiga - Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • ENVIGO CRS SAU 066, Centro Industrial Santiga – Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • ENVIGO CRS SAU 067, Centro Industrial Santiga – Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • ENVIGO CRS SAU 068, Centro Industrial Santiga – Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • ENVIGO CRS SAU 155, Centro Industrial Santiga - Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • ENVIGO CRS SAU 156, Centro Industrial Santiga - Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • Envigo Research Limited, Shardlow Business Park London Road DE72 2GD Shardlow Derbyshire United Kingdom
  • Envigo Research Limited 183, Shardlow Business Park London Road DE72 2GD Shardlow Derbyshire United Kingdom
  • Envigo Research Limited 24, Shardlow Business Park London Road DE72 2GD Shardlow Derbyshire United Kingdom
  • Envigo Research Limited 44, Shardlow Business Park London Road DE72 2GD Shardlow Derbyshire United Kingdom
  • Envigo Research Limited 50, Shardlow Business Park London Road DE72 2GD Shardlow Derbyshire United Kingdom
  • Evonik Degussa GmbH, Rellinghauser Strasse 1 - 11 C-ES 45128 Essen North Rhine-Westfalia Germany
  • Evonik Oxeno Antwerpen N.V., Tijsmanstunnel West 2040 Antwerpen Belgium
  • Evonik Performance Materials GmbH, Rellinghauser Strasse 1-11 45128 Essen Germany
  • Evonik Performance Materials GmbH - OR R1, Kirschenallee 64293 Darmstadt Germany
  • Evonik Resource Efficiency GmbH, Rellinghauser Strasse 1-11 45128 Essen Germany
  • ExxonMobil Chemical France SARL, Tour Manhattan, 5/6, Place de l'Iris 92400 Courbevoie France
  • ExxonMobil Petroleum & Chemical, BVBA, Polderdijkweg 2030 Antwerpen Belgium
  • Galata Chemicals GmbH, Chemiestrasse 22 68623 Lampertheim 06 Germany
  • Gazprom Marketing and Trading France18, 68 avenue des Champs-Elysées 75008 Paris France France
  • GCP APPLIED TECHNOLOGIES (UK) LIMITED, 580/581 Ipswich Road SL1 4EQ Slough United Kingdom
  • Gillette Poland International Sp. Z o.o., Nowy Jozefow 70 Street 94-406 Lodz Poland
  • Goodyear Dunlop Tires Operations S.A., Avenue Gordon Smith L-7750 Colmar-Berg Luxembourg
  • Goodyear Nederland B.V., Ledeboerstraat 21 5048 AC Tillburg Netherlands
  • Goodyear SA, Avenue Gordon Smith L-7750 Colmar-Berg Luxembourg
  • GRACE GmbH, In der Hollerhecke 1 67545 Worms Germany
  • Halliburton Manufacturing and Services Ltd, Halliburton House Howe Moss Crescent, Kirkhill Industrial Estate AB21 0GN Dyce Aberdeen United Kingdom
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Hitachi Chemical Europe GmbH, Berliner Allee 22 40212 Duesseldorf Germany Germany
  • ICL Europe Coöperatief U.A. (OR1), Koningin Wilhelminaplein 30 Prinsenhof 1062 KR Amsterdam Netherlands
  • INEOS Chemicals Lavera (O Imports), Rue de la Bienfaisance 13117 Lavera France
  • INEOS Manufacturing Deutschland GmbH, Alte Strasse 201 50769 Koeln Germany
  • INEOS nv, Haven 1053 -- Nieuwe Weg 1 2070 Zwijndrecht Belgium
  • INEOS Services Belgium NV (OR), Rue de Ransbeek 310 1120 Bruxelles Belgium
  • INEOS Styrolution Belgium, Haven 725, Scheldelaan 600 Scheldelaan 600 2040 Antwerpen 4 Belgium
  • INEOS Styrolution Europe GmbH, Mainzer Landstrasse 50 60325 Frankfurt am Main Germany
  • INEOS Styrolution Europe GmbH, Mainzer Landstr. 50 60325 Frankfurt am Main Germany
  • INEOS Styrolution Köln GmbH, Alte Str. 201 50769 Köln NRW Germany
  • Infineum Italia, Strada di Scorrimento 2 17047 Vado Ligure (SV) Italy
  • Innospec Limited (OR1), Innospec Manufacturing Park Oil Sites Road CH65 4EY Ellesmere Port Cheshire United Kingdom
  • Intertek Deutschland GmbH 03, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH 38, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH CTNI, Stangenstr. 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH DEX, Stangenstrasse 1 70771 Leinfelden-Echterdingen Baden-Württemberg Germany
  • Intertek Deutschland GmbH IGLT, Stangenstr. 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH TTRT, Stangenstr. 1 70771 Leinfelden-Echterdingen Germany
  • Isola GmbH, Isolastr 52353 Dueren NRW Germany
  • ITW Performance Polymers, A Division of ITW Ireland, Bay 150 Shannon Industrial Estate V14 DF82 Shannon Co. Clare Ireland
  • KIST Europe Forschungsgesellschaft mbH, Campus E 71 D-66123 Saarbruecken Germany
  • knoell Germany - OR - B15, Konrad-Zuse-Ring 25 68163 Mannheim Germany
  • Knoell NL_OR_057, Agro Business Park 75 6708 PV Wageningen Netherlands
  • Koopman International B.V., Distelweg 88 1031 HH Amsterdam Netherlands
  • Kuraray Europe GmbH (OR1), Philipp-Reis-Str. 4 65795 Hattersheim Germany
  • Kuraray Europe GmbH (OR2), Philipp-Reis-Str. 4 65795 Hattersheim Germany
  • L'isolante K-Flex S.p.A., Via Leonardo da Vinci, 36 20877 Roncello Monza Brianza Italy
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • LANXESS Deutschland GmbH in its legal capacity as Only Representative of ARLANXEO USA LLC, Kennedyplatz 1 50569 Köln Germany
  • LANXESS Sales Netherlands B.V., Kraanspoor 50 1033 SE Amsterdam Netherlands
  • LG Chem Europe GmbH, Lyoner str 15, Atricom C6, D-60528 Frankfurt am Main Germany
  • Luxcontrol S.A. (OR12), 1, Avenue des Terres Rouges 4004 Esch-sur-Alzette Luxembourg
  • Luxcontrol S.A. (OR13), 1, Avenue des Terres Rouges 4004 Esch-sur-Alzette Luxembourg
  • Luxcontrol S.A. (OR18), 1, Avenue des Terres Rouges - 4004 Esch-sur-Alzette - Luxembourg
  • Manufacture Française des Pneumatiques Michelin (OR CAN), Place des Carmes Déchaux 63040 Clermont Ferrand France
  • Manufacture Française des Pneumatiques Michelin (OR US), Place des Carmes Déchaux 63040 Clemront Ferrand France
  • MFPM Only Representative pour Michelin India Tamilnadu Tyres Private Limited, Place des Carmes Déchaux Site de Ladoux - Batiment G22 63040 Clermont-Ferrand France
  • MFPM SRI, Place des Carmes Déchaux Site de Ladoux 63040 Clermont-Ferrand France
  • Mitsubishi Chemical Europe GmbH, Willstätter Strasse 30 40549 Düsseldorf Germany
  • MOL Petrochemicals Private Company Limited by Shares, TVK-Ipartelep, TVK Központi Irodaház (136. sz. épület, hrsz: 2119/3) 3581 Tiszaujvaros Hungary
  • momaja s.r.o, Karolinská 650/1 186 00 Prague 8 Czech Republic
  • NAM&NAM Europe GmbH, Emil-Figge-Str.80 44227 Dortmund Germany
  • Nammo Raufoss AS, Enggata 37 2830 Raufoss Vestre Toten Norway
  • Naphtachimie SA, Place de la Coupole, 2 La Défence 6 92400 Courbevoie France
  • NetSun EU B.V., Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands
  • OMNOVA Solutions SAS (OR of OMNOVA Solutions Inc), 14 avenue des Tropiques ZA de Courtaboeuf 2, Villejust 91955 Courtaboeuf Cedex France
  • OMV Deutschland GmbH, Haiminger Straße 1 D-84489 Burghausen Germany
  • OMV Refining & Marketing GmbH, Trabrennstraße 6-8 A-1020 Wien Austria
  • Oy Nizhex Scandinavia Ltd, Wavulinintie 10 00210 HELSINKI Finland
  • Penman Consulting bvba 09, Avenue des Arts 10 B-1210 Brussels Belgium
  • Performance Materials Ibérica, S.L.U., Av. Diagonal Num. 571 08029 Barcelona Spain
  • Petrochemical Commercial Company (UK) Ltd, 24, GROSVENOR GARDENS SW1W 0DH LONDON EUROPE United Kingdom
  • PETROCHINA INTERNATIONAL (LONDON) CO., LTD, 11th Floor, The Adelphi, 1-11 John Adam Street, WC2N 6HT LONDON United Kingdom
  • Polski Koncern Naftowy ORLEN SA, ul. Chemików 7 09-411 Płock Poland
  • Procter & Gamble Manufacturing Berlin GmbH, Oberlandstr. 75 12099 Berlin Germany
  • Reach Only Representative Ltd (ecmpla), Booths Park 1 Chelford Road WA16 98GS Knutsford Cheshire United Kingdom
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford, Dublin 18, Ireland Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACHLaw Ltd, Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland
  • REACHLaw Ltd, Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • REACHLaw Ltd., Vänrikinkuja 3JK 21 02600 Espoo, Helsinki Finland Finland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • REPSOL POLIMEROS S.A., Monte Feio 7520-954 Sines Portugal
  • REPSOL QUÍMICA, Calle Mendez Alvaro, 44 28045 Madrid Madrid Spain
  • RHODIA OPERATIONS, 40 rue de la Haie Coq 93306 AUBERVILLIERS France
  • Richard Baker Harrison Ltd., Marsh Trees House Marsh Parade ST5 1BT Newcastle-under-Lyme Staffordshire United Kingdom
  • S.C.ENERGY BIO CHEMICALS S.A. BUCURESTI-SUCURSALA CAROM ONESTI, 33 Agricultori Str., floor 1, Ap2, 2nd District 1 Industriilor Str., C399 Administrative Wing, One 021482 Bucharest Romania
  • SABIC Innovative Plastics BV, Plasticslaan 1 4612 PX Bergen op Zoom Netherlands Netherlands
  • SABIC Petrochemicals B.V., Europaboulevard 1 6135 LD Sittard Netherlands
  • SABIC UK Petrochemicals Limited, Wilton Centre TS10 4RF Redcar Cleveland United Kingdom
  • Savarè I.C. S.r.l., via Polidoro da Caravaggio 3 20156 Milano Lombardia Italy
  • SCAS Europe S.A./N.V.151, Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • SCC GmbH, Am Grenzgraben 11
 55545 Bad Kreuznach
 Germany
  • Shell Chemicals Europe B.V., Weena 70 3012 CM Rotterdam Netherlands
  • Shell Nederland Chemie B.V., Vonderlingenweg 601, Att. G-J Dijkema WO 503200019 PO BOX 8610, 3009 AP Rotterdam Netherlands
  • Sinopec Europa GmbH, Messe Turm, Friedrich-Ebert-Anlage 49 60308 Frankfurt am Main Germany
  • SOLVENTIS LTD, Bank Terrace Gomshall Lane GU59HB Guildford Surrey United Kingdom
  • Specialty Electronic Materials Belgium, BVBA OR-1, Sneeuwbeslaan 20 / Pb10 B-2610 Wilrijk Belgium
  • Specialty Electronic Materials Netherlands B.V. OR-2, Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • Steptoe & Johnson LLP, Av Louise, 489 1050 Brussels Belgium
  • Sumitomo Corporation Europe Limited, 68 Upper Thames Street EC4V 3BJ London United Kingdom
  • Sumitomo Deutschland GmbH, Georg-Glock-Str. 8 40474 Düsseldorf Germany
  • Sustainability Support Services (Europe) AB, Markaskälsvägen 6 22647 Lund Sweden
  • Synthomer (UK) Limited, Central Road Templefields CM20 2BH Harlow Essex United Kingdom
  • Synthomer Trading Limited, 45 Pall Mall SW1Y 5JG London United Kingdom
  • Synthos Dwory 7 spółka z ograniczoną odpowiedzialnością spółka jawna, ul. Chemików 1 32-600 Oświęcim Poland
  • Teknor Apex BV, Mijnweg 1 Mijnweg 1, (P.O.Box 601, 6160 AP) 6167AC Geleen Please select Netherlands
  • Total Petrochemicals & Refining SA, Rue de l'Industrie,52 1040 Bruxelles Belgium
  • Total Polymer Solutions Ltd, Unit 5 Block 613 Jordanstown Road, Greenogue Business Park Co Rathcoole Dublin Ireland
  • Total Raffinage France, 2, place Jean Millier, La Défense 92400 Courbevoie France
  • Trinseo Netherlands B.V., H.H. Dowweg 5 4542 NM Hoek Netherlands
  • Trinseo Netherlands B.V. OR-1, H.H. Dowweg 5 4542 NM Hoek Netherlands
  • Trinseo Suomi OY, Urho Kekkosenkatu 7 B 00101 Helsinki Finland
  • Tyre Company Dębica SA., 1Maja 1 39-200 Dębica Poland
  • TÜV SÜD Iberia S.A.U. (046), Ronda Can Fatjó 13 Parc Tecnològic del Vallès 08290 Cerdanyola del Vallès Barcelona Spain
  • TÜV SÜD Iberia S.A.U. (048), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Spain
  • TÜV SÜD Iberia S.A.U. (059), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • VELOX GmbH, Brandstwiete 1 20457 Hamburg Germany
  • versalis S.p.A., P.zza Boldrini 1 20097 San Donato Milanese MILANO Italy
  • W. R. Grace S.A., 33 Route de Gallardon Boite Postale 39 28234 Epernon France
  • Wacker Chemie AG (OR_WCC), Johannes-Hess-Strasse 24 84489 Burghausen Germany
  • Xerox Manufacturing (Nederland) BV, Maasheseweg 89-91 5804 AB Venray Limburg Netherlands
  • Zeon Europe GmbH, Hansaallee 249 40549 Düsseldorf NRW Germany
  • Zeon Europe GmbH, Hansaallee 249 40459 Düsseldorf NRW Germany
  • [Confidential], [Confidential]
  • Chemical Inspection & Regulation Service Limited, Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland
  • DEKRA Assurance Services GmbH OR01, Handwerkstr. 15 70565 Stuttgart Germany
  • Henkel AG & Co. KGaA, Henkelstrasse 67 40191 Duesseldorf North-Rhine Westfalia Germany
  • Henkel Belgium Operations N.V., Havenlaan 16 1080 Brussels Belgium
  • Henkel Iberica S.A., Calle Bilbao 72-84 08005 Barcelona Spain
  • Henkel Ltd., Wood Lane End HP2 4RQ Hemel Hempstead, United Kingdom
  • Henkel Nederland B.V., Brugwal 11 3432 NZ Nieuwegein Netherlands
  • Henkel Polska Operations SP.z.o.o., Domaniewska 41 02-672 Warszawa Poland
  • Henkel Technologies France SAS, 161 Rue De Silly 92100 Boulogne-Billancourt France
  • INEOS Chemicals Grangemouth Ltd, PO Box 21 Bo,ness Road FK3 9XH Grangemouth Stirlingshire United Kingdom
  • Intertek Deutschland GmbH TCCT, Stangenstr. 1 70771 Leinfelden-Echterdingen Germany
  • Luxcontrol S.A. (OR19), 1, Avenue des Terres Rouges 4004 Esch-sur-Alzette Luxembourg
  • NetSun EU B.V., Blaak 40, Fifth Floor, 3011 TA Rotterdam Netherlands
  • SABIC Innovative Plastics Espana ScpA, Ctra. Cartagena-Alhama de Murcia km. 13. La Aljorra 30390 Cartagena Spain Spain
  • The Bergquist Company GmbH, Verbindungsweg 42 25469 Halstenbek Germany
  • Total Petrochemicals France SA, Immeuble Le Linéa 1, rue du Général Leclerc 92047 Paris La Défence Cedex France

Other names

  • ,3-butadiene
  • -
  • 1,3 Butadiene
  • 1,3, BUTADIENE
  • 1,3-Butadien
  • 1,3-Butadiene
  • 1,3-Butadiene (stabilized with TBC) (in cylinder without valve) [To use this product charged in cylinder, a valve is required which is sold separately (Product Code:V0030)]
  • 1,3-butadiene; buta-1,3-diene
  • 1,3-butadiène
  • 29.11.2010
  • Buta-1,3-diene
  • buta-1,3-diene; 1,3-butadiene
  • buta-1,3-dienne
  • Butadiene
  • Butadiene - BE
  • Butadiene 1,3-
  • Butadiene TSRC
  • Butadiene TSRCNT
  • Butadiene used as raw material to produce polymers
  • Not Applicable
  • 1,3-butadiene
  • Buta-1,3-diene
  • .alpha.,.gamma.-Butadiene
  • 1,3 -BD
  • 1,3 Butadiene
  • 1,3-BD
  • 1,3-Butadien
  • 1,3-Butadiene
  • 1,3-Butadiene (8CI, 9CI)
  • Aegis HFX
  • alpha,gamma-Butadiene
  • BD
  • BD (common trade name)
  • Biethylene
  • Bivinyl
  • Buta-1,3-diene
  • Buta-1,3diene
  • Butadien
  • Butadiene
  • Butadiene - E
  • BUTADIENE 1,3
  • Butadiene used as Raw material for polymers
  • Butadiene used to create polymers
  • Butadiene-1,3
  • Divinyl
  • Divinyl Erythrene
  • EK-1040D
  • Erythrene
  • erytrene
  • HF-0660I
  • HG-0760AT
  • HG-0760GP
  • HG-0760TV
  • Lustran
  • MP-0160 R
  • NCI-C50602
  • Not Applicable
  • O3039
  • Polymers imported by hROH
  • Pyrrolylene
  • QU-0191 S
  • Reclaimed Rubber
  • SD-0150
  • SD-0150 U
  • SD-0150 W
  • SD-0150GP
  • UBEPOL BR
  • VE-0812
  • VE-0856
  • VE-0856 U
  • VE-0858
  • VE-0860
  • VE-0860EX
  • VH-0800
  • VH-0800 E
  • VH-0810
  • VH-0815
  • Vinyl ethylene
  • Vinylethylene
  • VS-1821
  • 1,3-Butadiene
  • Butadiene

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Gaseous (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Physical state at 20°C and 1013 hPa
Gaseous (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 1 study processed
R Melting / freezing point
-108.9 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-109.15 °C

Boiling point

Study results
  • 2 studies submitted
  • 1 study processed
R Boiling point
-4.41 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
-4.15 °C

Density

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Vapour pressure

Study results
  • 2 studies submitted
  • 1 study processed
R Vapour pressure
217 - 255 kPa @ 16.85 - 21.85 °C [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
217 kPa @ 17 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
1.99 @ 25 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
1.99 @ 20 °C

Water solubility

Study results
  • 2 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
735 mg/L @ 20 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
735 mg/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Auto flammability

Study results
  • 2 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
420 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
419.85 °C

Flammability

Study results
  • 2 studies submitted
  • 1 study processed
C Interpretation of results
Extremely flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Extremely flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 3 studies submitted
  • 1 study processed
R Dissipation half life (DT50)
5.76 h [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
5.76 h
Degradation rate constant with OH radicals
43 200 m³ molecule-1 d-1

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 4 studies submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2 1
Other 1
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
9.8

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
51.6

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
7 150 - 7 900 Pa m³/mol @ 25 °C and 101.3 kPa [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
7 150 Pa.m³.mol-1 @ 20 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (1)
Intermittent releases (freshwater) No hazard identified (1)
Marine water No hazard identified (1)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) No hazard identified (1)
Sediment (marine water) No hazard identified (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No hazard identified (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 45 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (48 h) 33 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 33 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 2.21 mg/m³ carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 265.2 µg/m³ carcinogenicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
oral
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No study available
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: respiratory
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No study available
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Study data: inhalation
  • 10 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study 2
Supporting study 8
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Inhalation route - systemic effects:
Adverse effect observed NOAEC 2 212 mg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: in vivo
  • 15 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 6
Supporting study 7 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other 1
Data waiving
no waivers
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Inhalation route:
No adverse effect observed NOAEC 13 276 mg/m³ (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant