Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Peracetic acid
  • IUPAC name: ethaneperoxoic acid
  • Other names
EC / List no.:
201-186-8
CAS no.:
79-21-0
Index number:
607-094-00-8
Molecular formula:
C2H4O3
SMILES:
CC(=O)OO
InChI:
InChI=1S/C2H4O3/c1-2(3)5-4/h4H,1H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
30
Of which contain:
8 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance causes severe skin burns and eye damage, is very toxic to aquatic life, is a flammable liquid and vapour, is harmful if swallowed, is harmful in contact with skin, is harmful if inhaled and if heated may cause a fire.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic if swallowed, is toxic if inhaled, is very toxic to aquatic life with long lasting effects, causes serious eye damage and may cause respiratory irritation.

Breakdown of all 480 C&L notifications submitted to ECHA

Aquatic Acute 1 H400 Harmonised Classification
Flam. Liq. 3 H226 Harmonised Classification
Skin Corr. 1A H314 Harmonised Classification
Acute Tox. 4 H312 Harmonised Classification
Org. Perox. D H242 Harmonised Classification
Acute Tox. 4 H302 Harmonised Classification
Acute Tox. 4 H332 Harmonised Classification
Eye Dam. 1 H318
Acute Tox. 3 H301
Aquatic Chronic 1 H410
Acute Tox. 3 H331
STOT SE 3 H335
Org. Perox. C H242
Acute Tox. 2 H330
Aquatic Chronic 2 H411
https://echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 21 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:
There are 0 authorised Biocidal Product(s) that use this substance as an active ingredient

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000 - 10 000 tonnes per year.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is approved for use as a biocide in the EEA and/or Switzerland, for: human hygiene, disinfection, veterinary hygiene, food and animals feeds, drinking water, product preservation, preservation for liquid systems, controlling slimes.

This substance is used in the following products: washing & cleaning products.

Other release to the environment of this substance is likely to occur from: indoor use as reactive substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

This substance is used in the following products: washing & cleaning products, biocides (e.g. disinfectants, pest control products) and laboratory chemicals.

This substance is used in the following areas: health services, scientific research and development and agriculture, forestry and fishing. This substance is used for the manufacture of: textile, leather or fur and food products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, laboratory work, closed, continuous processes with occasional controlled exposure, non-industrial spraying, transfer of substance into small containers, roller or brushing applications and treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

This substance is used in the following products: washing & cleaning products, textile treatment products and dyes, biocides (e.g. disinfectants, pest control products), paper chemicals and dyes and water treatment chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, mixing in open batch processes and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: washing & cleaning products, paper chemicals and dyes, textile treatment products and dyes and perfumes and fragrances. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: health services. This substance is used for the manufacture of: textile, leather or fur, chemicals, pulp, paper and paper products and food products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: as processing aid and in processing aids at industrial sites.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, laboratory work and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • BIOXAL SA, Route des Varennes BP 30072 71103 CEDEX CHALON sur SAONE France
  • Brenntag GmbH, Messeallee 11 45131 Essen Germany
  • Cantel Medical (Italy) S.r.l., Via Laurentina 169 00071 Pomezia (RM) Italy
  • Christeyns NV, Afrikalaan 182 9000 Gent Belgium
  • Ecolab A.E., Fleming Street 15 GR-15123 Maroussi, Athens Greece
  • Ecolab Production France SAS, 94 Avenue Du General Patton Chalons-En-Champagne 51000 Chalons-En-Champagne France
  • Ecolab Production Italy s.r.l., Via Grandi 9/11 20089 Rozzano Italy
  • Evonik Peroxid GmbH, Industriestraße 1 9721 Weißenstein Carinthia Austria
  • ITW Novadan ApS, Platinvej 21 6000 Kolding Denmark
  • JSC "BS Chemical", Baltijos pr. 123-9 93224 Klaipeda Klaipeda Lithuania
  • Kemira Chemicals Oy, Harmajantie 3 P.O Box 7 FI-32741 SASTAMALA Finland
  • Kesla Pharma Wolfen GmbH, Keslastraße 1 06803 Bitterfeld-Wolfen Germany
  • MPD plus, s.r.o., Nabrezi Dr. Benese 2307 269 01 Rakovnik Czech Republic
  • PeroxyChem Spain s.l.u, Afueras s/n 50784 La Zaida Zaragoza Spain
  • Promox S.p.A., Via A. Diaz, 22/a - Peracetic Acid Plant Via A. Diaz, 21 - Organic Peroxide Plant 21038 Leggiuno - Varese Varese Italy
  • Rühl AG & Co. Chemische Fabrik KG, Hugenottenstraße 105 61381 Friedrichsdorf Germany
  • SaneChem sp.z o.o., Słodowiec 10/10 01-708 Warszawa Poland
  • Solimix, S.A., C/ Montseny 25, Polígono Industrial Sant Pere Molanta 08799 Olérdola Barcelona Spain
  • Solvay Chemie B.V., SCHEPERSWEG 1 6049 HERTEN Netherlands
  • SOPURA, rue de Trazegnies 199 6180 COURCELLES HAINAUT Belgium
  • Stockmeier Chemie Eilenburg GmbH & Co. KG, Gustav-Adolf-Ring 5 04838 Eilenburg Germany

Other names

  • -
  • Ethaneperoxoic acid
  • PAA
  • PERACETIC ACID
  • peracetic acid . . . %
  • peracetic acid ...%
  • Peracetic acid anhydrous
  • Peroxyacetic Acid
  • Peroxyacetic acid - Aqueous stabilised solution
  • Peroxyethanoic Acid
  • Reaction mass of 64-19-7 and 7722-84-1
  • Reaction mass of hydrogen peroxide and water
  • Peracetic acid
  • peracetic acid . . . %
  • ASPERIX®
  • Oxystrong
  • PERACLEAN®
  • Proxitane

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 3 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Odour
Other (100%) [1]
C Substance type
Organic (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 3 studies submitted
  • 2 studies processed
R Melting / freezing point
-73 - 18.8 °C @ 101.325 kPa [6]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
43.9 °C

Boiling point

Study results
  • 4 studies submitted
  • 3 studies processed
R Boiling point
20 - 110 °C @ 13.332 - 1 013.25 hPa [9]

Type of Study provided
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
105 °C

Density

Study results
  • 4 studies submitted
  • 3 studies processed
R Density
1.231 - 1.278 g/cm³ @ -10 - 20 °C [3]
R Relative density
1.13 - 1.15 @ 20 °C [2]

Type of Study provided
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.135

Vapour pressure

Study results
  • 3 studies submitted
  • 3 studies processed
R Vapour pressure
14.1 - 26 hPa @ 20 °C [4]

Type of Study provided
Studies with data
Key study 1 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
14.1 hPa @ 19.85 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 3 studies processed
R Log Pow
-1.2 - 1.3 @ 25 °C and pH 5 - 9 [8]

Type of Study provided
Studies with data
Key study 1 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
-0.26 @ 20 °C

Water solubility

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
10 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Study results
  • 1 study submitted
  • 1 study processed
R Acetone
500 g/L @ 25 °C [1]
R Ethyl acetate
20 - 25 g/L @ 25 °C [1]
R Isopropanol
500 g/L @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
47.7 mN/m @ 150 mg/L

Flash point

Study results
  • 1 study submitted
  • 1 study processed
R Flash point
68 - 83 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
68 °C

Auto flammability

Study results
  • 2 studies submitted
  • 2 studies processed
R Autoflammability / self-ignition
280 - 435 °C @ 100.4 - 100.6 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 3 studies submitted
  • 2 studies processed
C Interpretation of results
Non-explosive (100%) [2]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
Yes (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Dissociation constant

Study results
  • 3 studies submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
8.24 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
pKa at 20 °C
8.24

Viscosity

Study results
  • 3 studies submitted
  • 3 studies processed
R Other:
2.891 - 8.357 [3]
R kinematic viscosity (in mm²/s)
1.22 - 1.5 [2]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Static viscosity at 20 °C
2.89 mm²/s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 2 studies submitted
  • 1 study processed
R Dissipation half life (DT50)
95.26 h [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 1 1
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
22 min
Degradation rate constant with OH radicals
4.022 cm³ molecule-1 s-1

Hydrolysis

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life for hydrolysis
31.7 h @ 25 °C

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 4 studies submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half-life in freshwater
5 min @ 20 °C

Biodegradation in soil

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
0.217 Pa m³/mol @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0.217 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Study results
  • 1 study submitted
  • 1 study processed
% Distribution in Media:
R Air 0.01 % [1]
R Water 99.95 % [1]
R Soil 0 % [1]
R Sediment 0.04 % [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 94 ng/L (1)
Intermittent releases (freshwater) 1.6 µg/L (1)
Marine water 4.9 ng/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 51 µg/L (1)
Sediment (freshwater) 77 ng/kg sediment dw (1)
Sediment (marine water) 15 ng/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 320 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 10 studies submitted
  • 3 studies processed
P/RResults
LC50 (4 days) 78 - 11 000 µg/L [4]
NOEC (4 days) 24 - 6 700 µg/L [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 6
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
530 µg/L
LC50 for marine water fish
11 mg/L

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (33 days) 2.2 µg/L [1]
NOEC (9 days) 22.4 µg/L [1]
NOEC (8 days) 22.4 - 22 400 ng/L [2]
LOEC (33 days) 7.5 µg/L [1]
LOEC (9 days) 22.4 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater fish
940 ng/L

Short–term toxicity to aquatic invertebrates

Study results
  • 12 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 270 - 730 µg/L [2]
EC100 (48 h) 1.4 - 1.6 mg/L [2]
NOEC (48 h) 130 - 560 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 8
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
730 µg/L
EC50 / LC50 for marine invertebrates
270 µg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (21 days) 12.1 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
12.1 µg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 160 µg/L [1]
NOEC (72 h) 61 µg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
160 µg/L
EC10 or NOEC for freshwater algae
61 µg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (3 h) 5.1 - 38.6 mg/L [2]
EC50 (30 min) 5.3 mg/L [1]
NOEC (3 h) 16.7 mg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
5.1 mg/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
LC50 (14 days) 1 g/kg soil dw [1]
LC0 (14 days) 1 g/kg soil dw [1]
LC100 (14 days) 1 g/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
1 g/kg soil dw

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
NOEC (21 days) 180 mg/kg soil dw [3]
EC50 (21 days) 320 - 413 mg/kg soil dw [3]
EC25 (21 days) 278 - 363 mg/kg soil dw [3]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
320 mg/kg soil dw

Toxicity to soil microorganisms

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
NOEC (28 days) 295.2 mg/kg soil dw [1]
NOEC (28 h) 933.6 mg/kg soil dw [1]
EC25 (28 days) 813 mg/kg soil dw [1]
EC25 (28 h) 933.6 mg/kg soil dw [1]
EC50 (28 days) 933.3 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50
933.3 mg/kg soil dw

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 560 µg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 560 µg/m³ irritation (respiratory tract)
Local Effects
Long-term: (DNEL) 560 µg/m³ sensitisation (respiratory tract)
Acute /short term: (DNEL) 560 µg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
EYE Exposure
High hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 280 µg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 280 µg/m³ irritation (respiratory tract)
Local Effects
Long-term: (DNEL) 280 µg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 280 µg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: High hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.25 mg/kg bw/day developmental toxicity / teratogenicity
Acute /short term: (DNEL) 1.25 mg/kg bw/day developmental toxicity / teratogenicity
EYE Exposure
High hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 21 studies submitted
  • 13 studies processed
P/RResults
LD50 5.8 - 5 000 mg/kg bw (rat) [54]
M/CInterpretations of results
Harmful [9]

Type of Study provided
oral
Studies with data
Key study 13
Supporting study 3 2
Weight of evidence
Other 2 1
Data waiving
no waivers
inhalation
  • 14 studies submitted
  • 1 study processed
P/RResults
LC50 (4 h) 186 - 4 080 mg/m³ air (rat) [4]
M/CInterpretations of results
Harmful [1]

inhalation
Studies with data
Key study 2
Supporting study 10 1
Weight of evidence
Other 1
Data waiving
no waivers
dermal
  • 10 studies submitted
  • 3 studies processed
P/RResults
LD50 17.8 - 2 000 mg/kg bw (rat) [2]
LD50 50.9 - 1 990 mg/kg bw (rabbit) [12]
M/CInterpretations of results
Practically nontoxic [1]

dermal
Studies with data
Key study 3
Supporting study 4
Weight of evidence
Other 3
Data waiving
no waivers
other routes
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 212 mg/kg bw (mouse) [1]

other routes
Studies with data
Key study
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 50 mg/kg bw
Inhalation route:
Adverse effect observed LC50 204 mg/m³
Dermal route:
Adverse effect observed LD50 1 147 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 15 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 4
Supporting study 9
Weight of evidence
Other 2
Data waiving
no waivers
Study data: eye
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (corrosive)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other 1
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 5 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 1.17 - 38 mg/kg bw/day [4]
NOAEL (rat): 200 mg/L drinking water [1]
LOAEL (rat): 3.37 - 67.4 mg/kg bw/day [2]
NOEL (rat): 0.37 - 7.4 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 1 2
Data waiving
no waivers
Study data: inhalation
  • 8 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence 7
Other 1
Data waiving
no waivers
Study data: dermal
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 23.4 mg/kg bw/day (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 29 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 6
Supporting study
Weight of evidence 1
Other 22
Data waiving
no waivers
Study data: in vivo
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 4
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: developmental
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 12.5 mg/kg bw/day (subchronic, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant