Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
201-143-3
CAS no.:
78-79-5
Index number:
Molecular formula:
C5H8
SMILES:
CC(=C)C=C
InChI:
InChI=1S/C5H8/c1-4-5(2)3/h4H,1-2H2,3H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
6
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance may cause cancer, is an extremely flammable liquid and vapour, is suspected of causing genetic defects and is harmful to aquatic life with long lasting effects.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic to aquatic life with long lasting effects.

Breakdown of all 2546 C&L notifications submitted to ECHA

Flam. Liq. 1 H224 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Muta. 2 H341 Harmonised Classification
Aquatic Chronic 3 H412 Harmonised Classification
Aquatic Chronic 2 H411
Eye Irrit. 2 H319
Asp. Tox. 1 H304
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (100% of REACH registrations).
  • M
Suspected to be Mutagenic (Harmonised C&L).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 4 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.

This substance is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, in materials as fuel sources, with limited exposure to unburned product to be expected and closed batch processing in synthesis or formulation.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: for thermoplastic manufacture, of substances in closed systems with minimal release, as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites and manufacturing of the substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures, formulation in materials, in processing aids at industrial sites, in the production of articles, as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • DuPont Specialty Products GmbH & Co. KG, Hugenottenallee 175 63263 Neu-Isenburg Hesse Germany
  • ExxonMobil Chemical France SARL, 20 Rue Paul Heroult 92000 Nanterre France
  • ExxonMobil Petroleum & Chemical BV, Polderdijkweg 2030 Antwerpen Belgium
  • POLYNT S.p.A., via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy
  • Avery Dennison België bvba STD, Tieblokkenlaan 1 2300 Turnhout Belgium
  • Evonik Operations GmbH, Rellinghauser Straße 1-11 45128 Essen Germany
  • Henkel AG & Co. KGaA, Henkelstrasse 67 40191 Duesseldorf North-Rhine Westfalia Germany
  • Henkel Ltd., Wood Lane End HP2 4RQ Hemel Hempstead, United Kingdom
  • Luxcontrol S.A. (OR19), 1, Avenue des Terres Rouges 4004 Esch-sur-Alzette Luxembourg

Substance names and other identifiers

1,3-Butadiene, 2-methyl-
Other
2-Methyl-1,3-butadiene
C&L Inventory, Other, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use
2-Methylbutadiene
Other
2-Methyldivinyl
Other
3-Methyl-1,3-butadiene
Other
beta-Methylbivinyl
Other
Isopentadiene
Other
isoprene (stabilised)
C&L Inventory
isoprene (stabilised); 2-methyl-1,3-butadiene
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Physical, Biological and Chemical Agents & Processes and Work, General Product Safety Directive - Hazardous Substances, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties
Isoprene (stabilized)
Cosmetic Products Regulation, Annex II - Prohibited Substances
ISOPRENE, STABILIZED
Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
isoprene; 2-methyl-1,3-butadiene
FCM Active and Intelligent Materials - CMRs not allowed for use, Aerosols Directive - Flammable Contents - Labelling Requirements, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes
2-methyl-1,3-butadien (da)
C&L Inventory
2-methylbuta-1,3-dien (cs)
C&L Inventory
2-metil-1,3-butadien (hr)
C&L Inventory
2-metil-1,3-butadiena (ro)
C&L Inventory
2-metil-1,3-butadienas (lt)
C&L Inventory
2-metil-1,3-butadiene (it)
C&L Inventory
2-metil-1,3-butadieno (es)
C&L Inventory
2-metil-1,3-butadién (hu)
C&L Inventory
2-metilbutadiēns-1,3 (lv)
C&L Inventory
2-metyl-1,3-butadien (no)
C&L Inventory
2-metylbuta-1,3-dién (sk)
C&L Inventory
2-metylobuta-1,3-dien (pl)
C&L Inventory
2-metyyli-1,3-butadieeni (fi)
C&L Inventory
2-metüül-1,3-butadieen (et)
C&L Inventory
2-méthyl-1,3-butadiène (fr)
C&L Inventory
2-μεθυλο-1,3-βουταδιένιο (el)
C&L Inventory
2-метил-1,3-бутадиен (bg)
C&L Inventory
isopreen (nl)
C&L Inventory
Isopreen (stabiliseeritud) (et)
C&L Inventory
isopreeni (fi)
C&L Inventory
isopren (da)
C&L Inventory
isopren (stabilisert) (no)
C&L Inventory
Isopren (stabilisiert) (de)
C&L Inventory
isopren (stabilizovaný) (cs)
C&L Inventory
isoprene (it)
C&L Inventory
isopreno (es)
C&L Inventory
isopreno (estabilizado) (pt)
C&L Inventory
isoprène (stabilisé)2-méthyl-1,3-butadiène (fr)
C&L Inventory
izopren (pl)
C&L Inventory
izopren (stabilizirani) (hr)
C&L Inventory
izopren(stabilizat) (ro)
C&L Inventory
izoprenas (stabilus) (lt)
C&L Inventory
izoprén (stabilizovaný) (sk)
C&L Inventory
izoprén (stabilizált) (hu)
C&L Inventory
izoprēns, stabilizēts (lv)
C&L Inventory
ισοπρένιο (σταθεροποιημένο) (el)
C&L Inventory
изопрен (стабилизиран) (bg)
C&L Inventory
2-Methyl-buta-1,3-diene
C&L Inventory
2-methylbuta-1,3-diene
Registration dossier, Other
IPM
Registration dossier
Isoprene (stabilized with TBC)
C&L Inventory
Methyl-1,3-butadiene
C&L Inventory
not appliable
Registration dossier
not applicable
Registration dossier
Butyl Reclaimed Rubber
Registration dossier
Reclaimed Rubber
Registration dossier
rubber powder
Registration dossier
tire reclaimed rubber
Registration dossier
tread tire reclaim
Registration dossier
whole tire reclaim
Registration dossier
601-014-00-5
Index number
C&L Inventory
78-79-5
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, Aerosols Directive - Flammable Contents - Labelling Requirements, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Ambient Air Quality Directive, Annex X - Ozone Precursor Substances, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
78006-92-5
CAS number
Other
823271-95-0
CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Data not provided by the registrant

Melting/freezing point

Data not provided by the registrant

Boiling point

Data not provided by the registrant

Density

Data not provided by the registrant

Vapour pressure

Data not provided by the registrant

Partition coefficient

Data not provided by the registrant

Water solubility

Data not provided by the registrant

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Data not provided by the registrant

Flash point

Data not provided by the registrant

Auto flammability

Data not provided by the registrant

Flammability

Data not provided by the registrant

Explosiveness

Data not provided by the registrant

Oxidising

Data not provided by the registrant

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Data not provided by the registrant

Viscosity

Data not provided by the registrant

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Data not provided by the registrant

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Data not provided by the registrant

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Data not provided by the registrant

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

Data not provided by the registrant

Short–term toxicity to fish

Data not provided by the registrant

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Data not provided by the registrant

Long–term toxicity to aquatic invertebrates

Data not provided by the registrant

Toxicity to aquatic algae and cyanobacteria

Data not provided by the registrant

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Data not provided by the registrant

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

Data not provided by the registrant

Toxicokinetics, metabolism, and distribution

Data not provided by the registrant

Acute toxicity

Data not provided by the registrant

Irritation / corrosion

Data not provided by the registrant

Sensitisation

Data not provided by the registrant

Repeated dose toxicity

Data not provided by the registrant

Genetic toxicity

Data not provided by the registrant

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Data not provided by the registrant

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant