Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Citric acid
  • IUPAC name: 2-hydroxypropane-1,2,3-tricarboxylic acid
  • Other names
EC / List no.:
201-069-1
CAS no.:
77-92-9
Index number:
Molecular formula:
C6H8O7
SMILES:
OC(=O)CC(O)(CC(O)=O)C(O)=O
InChI:
InChI=1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
36
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes serious eye damage, causes skin irritation and may cause respiratory irritation.

Breakdown of all 3595 C&L notifications submitted to ECHA

Eye Irrit. 2 H319
Not Classified
Eye Dam. 1 H318
Skin Irrit. 2 H315
STOT SE 3 H335
Skin Corr. 1B H314
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 104 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:
There are 0 authorised Biocidal Product(s) that use this substance as an active ingredient

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100 000+ tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is approved for use as a biocide in the EEA and/or Switzerland, for: disinfection.

This substance is used in the following products: washing & cleaning products, air care products, cosmetics and personal care products, polishes and waxes, fillers, putties, plasters, modelling clay, photo-chemicals and coating products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), production of mixtures or articles by tabletting, compression, extrusion or pelletisation and potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens).

Release to the environment of this substance can occur from industrial use: in the production of articles. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).

This substance can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), wood (e.g. floors, furniture, toys), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys) and leather (e.g. gloves, shoes, purses, furniture). This substance is intended to be released from scented: paper products.

This substance is used in the following products: washing & cleaning products, polishes and waxes, coating products, fillers, putties, plasters, modelling clay, fertilisers, photo-chemicals and cosmetics and personal care products.

This substance is used in the following areas: building & construction work, agriculture, forestry and fishing, health services, mining and formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: machinery and vehicles and furniture.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, non-industrial spraying, hand mixing with intimate contact only with personal protective equipment available, mixing in open batch processes, industrial spraying and transfer of substance into small containers.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance is used in the following products: polishes and waxes, washing & cleaning products, fertilisers, air care products, cosmetics and personal care products, adhesives and sealants, photo-chemicals, coating products and fillers, putties, plasters, modelling clay.

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, transfer of substance into small containers and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials and in processing aids at industrial sites. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.

This substance is used in the following products: pH regulators and water treatment products, washing & cleaning products, polishes and waxes and water treatment chemicals.

This substance is used in the following areas: mining, health services, building & construction work and formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: machinery and vehicles, chemicals, fabricated metal products, metals, electrical, electronic and optical equipment and textile, leather or fur.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, treatment of articles by dipping and pouring, industrial spraying, mixing in open batch processes, batch processing in synthesis or formulation with opportunity for exposure, closed batch processing in synthesis or formulation and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release, in the production of articles, as processing aid and formulation of mixtures. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, transfer of substance into small containers, closed processes with no likelihood of exposure, industrial spraying, treatment of articles by dipping and pouring, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, laboratory work and hand mixing with intimate contact only with personal protective equipment available.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials and in processing aids at industrial sites.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If eye irritation persists: (follow instructions). Rinse cautiously with water for several minutes. If in contact with eyes, remove contact lenses if present and easy to do - continue rinsing. If in eyes: follow instructions specified by manufacturer/supplier. Get medical advice/attention.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • A.S. Watson (Health & Beauty Continental Europe) B.V., Evora, Postbus 34, 3927 Zl Renswoude Netherlands
  • A.S. Watson (Health & Beauty Ireland) Limited, 70 Sir John Rogerson’s Quay D02 Dublin 2 Ireland
  • Abbott Diagnostics GmbH, Max Planck Ring 2 D-65205 Delkenheim Germany
  • Access Business Group International BV, Celsiusweg 20 Industrial Estate 4212 5928 PR Venlo Netherlands
  • ADM Services B.V., Kingsfordweg 83 1043 GP Amsterdam Netherlands
  • Advanced Refining Technologies GmbH, In der Hollerhecke 1 67547 Worms Germany
  • AgroFresh Holding France SAS, 23-25 Avenue Mac-Mahon 75017 Paris France
  • ALFARIN QUIMICA, S.A., C/. Ibiza 35 -5º C 28009 MADRID Spain
  • ARCHROMA IBÉRICA, S.L., ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain
  • Asahi Chemical Europe s,r,o,, Lužná 716/2 16000 Praha 6 - Vokovice Praha Czech Republic
  • Ashland Services BV (0311), Noordweg 9 3336 LH Zwijndrecht Netherlands
  • Atlantic Chemicals Trading GmbH, Hermannstr. 46 20095 Hamburg Germany
  • Avantor Performance Materials Poland S.A., Sowińskiego 11 44-100 Gliwice Poland
  • B-Lands Consulting (811232-9), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • B-Lands Consulting (811506-9), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811508-5), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811509-8), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811512-8), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811527-4), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811547-6), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • BASF Espanola S.L., Calle Can Ràbia, n. 3-5 8017 Barcelona Spain
  • BASF Health and Care Products France S.A.S., 49, Avenue Georges Pompidou 92593 Levallois-Perret Cedex France
  • BASF Italia S.p.A., Via Marconato 8 20811 Cesano Maderno Italy
  • BASF Personal Care and Nutrition GmbH, Henkelstr. 67 40589 Düsseldorf Germany
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BBCA BELGIUM N.V., Hoeikensstraat 2 B -2830 Willebroek Antwerp Belgium
  • Beckman Coulter France SAS, Paris Nord 2 33 Rue des Vanesses 95942 Roissy CDG CEDE France
  • Brenntag GmbH, Messeallee 11 45131 Essen Germany
  • BÜFA Chemikalien GmbH & Co. KG, An der Autobahn 14 27798 Hude / Altmoorhausen Germany
  • C.S.B. GmbH, Düsseldorfer Str. 113 47809 Krefeld Germany
  • Cargill B.V., Evert van de Beekstraat 378 1118 CZ Amsterdam Schiphol North Holland Netherlands
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemours Netherlands B.V., Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • Chemservice GmbH - (Q1Z2), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • CIMACHEM GmbH, Kupferbergstr. 59 67292 Kirchheimbolanden Germany
  • Clariant Produkte (Deutschland) GmbH, Am Unisys-Park 1 65843 Sulzbach am Taunus Germany
  • Colgate-Palmolive Services (Poland) sp. z o.o. / OR Guatemala, ul. Tasmowa 7 02-677 Warsaw Poland
  • D&F b.v., Newtonweg 6 4104 BK Culemborg Netherlands
  • DAABON Europa GmbH, Nettegasse 80 50259 Pulheim Germany
  • DEKRA Assurance Services GmbH OR07, Handwerkstr. 15 70565 Stuttgart Germany
  • Denka Chemicals GmbH, Kaiserswerther Str. 183 40474 Dusseldorf Germany Germany
  • DeSangosse Ltd, Hillside Mill Quarry Lane CB25 0LU Swaffham Bulbeck Cambridge United Kingdom
  • Donauchem GmbH, Lisztstraße 4 1037 Vienna Vienna Austria
  • DOW AGROSCIENCES B.V. (BE), Sneeuwbeslaan 20 – bus 10 2610 Wilrijk Belgium
  • DOW AGROSCIENCES ITALIA S.R.L., Via F. Albani 65 20148 Milano Italy
  • DOW AGROSCIENCES LIMITED, CPC2 Capital Park, Fulbourn Cambridge CB21 5XE Cambridgeshire United Kingdom
  • DOW AGROSCIENCES S.A.S., 6 rue Jean-Pierre Timbaud, Immeuble Le Campus, Bâtiment.A 78180 Montigny-le-Bretonneux France
  • Dow Belgium B.V.B.A., Sneeuwbeslaan 20, bus 10 2610 Wilrijik Belgium Belgium
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • Du Pont (U.K.) Limited, London Road 4th Floor, Kings Court SG1 2NG Stevenage Hertfordshire United Kingdom
  • Du Pont de Nemours (Deutschland) GmbH, Hugenottenallee 173-175 D-63263 Neu-Isenburg Hesse Germany
  • DuPont Solutions (France) SAS, 22, rue Brunel 75017 Paris France
  • Ecolab Production Belgium B.V.B.A., Havenlaan 4 3980 Tessenderlo Belgium
  • Gadot Bio-Chem (Europe) BV, Hoefsmidstraat 41 3194 AA Hoogvliet Netherlands
  • Gadot Bio-Chem (Europe) BV, 41 Hoefsmidstraat 3194AA Hoogvliet Netherlands
  • GOJO Industries – Europe Ltd., Units 5 & 6 Stratus Park Brinklow MK10 0DE Milton Keynes Buckinghamshire United Kingdom
  • GRACE GmbH, In der Hollerhecke 1 67545 Worms Germany
  • Grillo-Werke AG, Weseler Straße 1 47169 Duisburg Germany
  • H.B. S.R.L., via vespucci 7 36071 ARZIGNANO VICENZA Italy
  • HACH LANGE GMBH, Koenigsweg 10 14163 Berlin Germany
  • Hall & Associates (Marketing) Ltd, 2 Tudor Court YO26 6RS York United Kingdom
  • Honeywell Belgium NV, Gaston Geenslaan 14 3001 Heverlee Belgium Belgium
  • Huntsman Textile Effects (Germany) GmbH, Rehlinger Str. 1 D-86462 Langweid a.Lech Germany
  • Imerys Minerals International Sales, imerys minerals limited Par moor centre, Par moor road PL242SQ Par CORNWALL Luxembourg
  • INDUKERN S.A., Alta Ribagorza, 6-8 08820 El Prat de Llobregat Barcelona Spain
  • Interplay UK Ltd, Interplay UK Ltd Unit D, Meter House, Fieldhouse Lane, SL7 1LW Marlow Bucks United Kingdom
  • Intertek Deutschland GmbH CGDN, Stangenstr.1 70771 Leinfelden-Echterdingen Germany
  • Jungbunzlauer Austria AG, Factory Pernhofen 2064 Wulzeshofen Austria
  • Jungbunzlauer Ladenburg GmbH, Dr. Albert-Reimann-Strasse 18 68526 Ladenburg Germany
  • Koopman International B.V., Distelweg 88 1031 HH Amsterdam Netherlands
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • LinmarkOR91, Linmark Consulting Ltd Hillock, Ballut Street STJ 1373 St Julian's Malta
  • Magnesium Elektron Limited, PO Box 6, Lumns Lane M27 8LS Swinton Manchester United Kingdom
  • Merck KGaA, Frankfurter Strasse 64293 Darmstadt Germany
  • Nortem Chem, SL, C/ Alexander Humboldt, 12 P.I. Salinas de Poniente 11500 El Puerto de Santa Maria Spain
  • Oskar Berg Basischemikalien GmbH, Kardinal-Galen-Str. 56 47051 Duisburg Germany
  • PRODUCTOS CAPILARES L'OREAL S.A., Calle Josefa Valcarcel num. 48 28027 MADRID Spain
  • REACh ChemConsult GmbH, Strehlener Str. 14 01069 Dresden Germany
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • RFI Food Ingredients Handelsgesellschaft mbH, Kennedydamm 24 40476 Duesseldorf NRW Germany
  • RHI Feuerfest GmbH, Kranichberggasse 6 1120 Vienna Austria
  • Rossmann SDP Sp. z o.o., ul.Św.Teresy 109 91-222 Łódź Łódź Poland
  • Rotam Crop Protection Europe SAS, 75 cours Albert Thomas-6e avenue/Batiment D 69003 Lyon France
  • S.A. CITRIQUE BELGE N.V., Pastorijstraat 249 3300 TIENEN Belgium
  • SHELL CATALYSTS & TECHNOLOGIES BELGIUM, Pantserschipstraat 331 9000 Gent Belgium
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom
  • Soapland GmbH & Co. OHG, Am weißen Haus 1 56626 Andernach Germany
  • Sodasan GmbH, Rudolf-Diesel-Str.19 26670 Uplengen-Jübberde Germany
  • Solberg Industri AS, Rosenlund 61 1617 FREDRIKSTAD Norway
  • Specialty Electronic Materials Netherlands B.V., Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • Specialty Electronic Materials Netherlands B.V. OR-1, Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • Specialty Electronic Materials Netherlands B.V. OR-6, Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • STERIS Ireland Limited, IDA Business and Technology Park Country Offialy R35 X865 Tullamore Ireland
  • Tate&Lyle slovakia s.r.o.-3, Boleráz 114 91908 Boleráz Slovakia
  • Tate&Lyle Slovakia s.r.o.-6, Boleráz 114 91908 Boleráz Slovakia
  • TIGI, Unilever House Springfield Drive KT22 7GR Leatherhead Surrey United Kingdom
  • TJ Morris Ltd, Portal Way L11 0JA Liverpool Merseyside United Kingdom
  • TSGE_7-2, Concordia House, St. James Business Park Grimbald Crag Court HG5 8QB Knaresborough North Yorkshire United Kingdom
  • Versum Materials Netherlands B.V., Kanaalweg 15 PO Box 3193 3502 GD Utrecht Netherlands
  • [Confidential], [Confidential]
  • B-Lands Consulting (811507-2), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811535-9), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811540-5), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811619-6), World Trade Center, 5 Place Robert Schuman - BP 1516 38025 Grenoble France France

Other names

  • -
  • 1,2,3-Propanetricarboxylic acid, 2-hydroxy-
  • 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, monohydrate
  • 19147_77-92-9
  • 2-hydorxypropane-1,2,3-tricarboxylic acid
  • 2-hydroxy -1,2,3 propane tricarboxylic acid
  • 2-hydroxy-1,2,3-propane tricarboxylic acid
  • 2-HYDROXY-1,2,3-PROPANETRICARBOXYLIC ACID
  • 2-hydroxy-1,2,3-propanetricarboxylic acid monohydrate
  • 2-Hydroxypropan-1,2,3-tricarbonsäure
  • 2-HYDROXYPROPANE-1, 2, 3-TRICARBOXYLIC ACID
  • 2-hydroxypropane-1,2,3-tricarboxylic
  • 2-hydroxypropane-1,2,3-tricarboxylic ...
  • 2-Hydroxypropane-1,2,3-tricarboxylic acid
  • 2-hydroxypropane-1,2,3-tricarboxylic acid anhydrous
  • 2-hydroxypropane-1,2,3-tricarboxylic acid hydrate
  • 2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid
  • 2-hydroxypropane-1,2,3-tricarboxylic acid.
  • 2-hydroxypropane-1,2,3-trioic acid
  • 2-hydroxypropane-l,2,3-tricarboxylic acid
  • 2-hydroxypropane.1,2,3-tricaboxylic
  • 201-069-1
  • 3-carbossi-3-idrossi-1,5-pentandioic acid
  • 3-carboxy-3-hydroxy pentanedioic acid
  • 3-Carboxy-3-hydroxypentanedioic acid
  • 3-hydroxy-1,2,3-propanetricarboxylic acid, anhydrous
  • 3-hydroxy-3-carboxy-1,5-pentanedioic acid
  • 3-hydroxy-3-carboxy-1,5-pentanedioic acid.
  • 3-hydroxy-3-carboxy-1,5-pentaneioicacid
  • 77-92-9
  • Acide citrique
  • acido 3-carbossi-3-idrossi-1,5-pentandioico
  • acido citrico anidro
  • Anhydrous Citric Acid
  • Anhydrous form: 2-hydroxypropane-1,2,3-tricarboxylic acidMonohydrated form: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, monohydrate
  • CITRIC ACID
  • CITRIC ACID ANHYDROUS
  • CITRIC ACID MONOHYDRATE
  • CITRIC ACID, MONOHYDRATE
  • citric acid; 3-hydroxy-3-carboxy-1,5-pentanedioic acid;
  • citric acid 
  • CITROMSAV-MONOHIDRÁT
  • Citronensäure, wasserfrei
  • hydroxypropene - 1,2,3 - tricarboxylic
  • ORGANIC ACID
  • Acide citrique
  • Acide citriqueACIDO CITRICO MONOIDRATOCITRIC ACIDCitric Acid AnhydrousCitric Acid MonohydrateCitronensäure-MonohydratÁcido citrico
  • ACIDO CITRICO MONOIDRATO
  • CITRIC ACID
  • Citric Acid Anhydrous
  • Citric Acid Monohydrate
  • Citronensäure-Monohydrat
  • Ácido citrico

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [1]
C Form
Crystalline (100%) [1]
C Odour
Odourless (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 2 studies submitted
  • 1 study processed
R Melting / freezing point
153 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
152.85 °C

Boiling point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 1 study submitted
  • 1 study processed
R Relative density
1.67 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.665

Vapour pressure

Study results
  • 1 study submitted
  • 1 study processed
R Vapour pressure
0 Pa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 5
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 8 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 6 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 3 studies submitted
  • 1 study processed
C Interpretation of results
Non flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Dissociation constant

Study results
  • 2 studies submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
3.13 - 6.4 @ 25 °C [3]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 3 studies submitted
  • 3 studies processed
C Interpretation of results
Readily biodegradable (67%), Inherently biodegradable (33%) [3]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 440 µg/L (1)
Intermittent releases (freshwater) -
Marine water 44 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 1 g/L (1)
Sediment (freshwater) 34.6 mg/kg sediment dw (1)
Sediment (marine water) 3.46 mg/kg sediment dw (1)
Hazard for Air
Air -
Hazard for Terrestrial Organism
Soil 33.1 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning -

Short–term toxicity to fish

Study results
  • 5 studies submitted
  • 1 study processed
P/RResults
LC50 (48 h) 440 - 760 mg/L [2]
LC0 (48 h) 200 - 620 mg/L [2]
LC100 (48 h) 600 - 800 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 3 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
440 mg/L

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
LC50 (24 h) 1.535 g/L [1]
LC0 (24 h) 1.206 g/L [1]
LC100 (24 h) 2.083 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

Data not provided by the registrant

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Acute toxicity

Study results
oral
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 5 400 mg/kg bw (mouse) [1]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
dermal
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Repeated dose toxicity

Study results
Study data: oral
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study 3 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: inhalation
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2
Supporting study 2
Weight of evidence 1
Other
Data waiving
no waivers
Study data: in vivo
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study 2 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study 4 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant