Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Propane-1,2-diol
  • IUPAC name: propane-1,2-diol
  • Other names
EC / List no.:
200-338-0
CAS no.:
57-55-6
Index number:
Molecular formula:
C3H8O2
SMILES:
CC(O)CO
InChI:
InChI=1/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
69
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.
According to the majority of notifications provided by companies to ECHA in CLP notifications no hazards have been classified.

Breakdown of all 8890 C&L notifications submitted to ECHA

Not Classified
Eye Irrit. 2 H319
Aquatic Chronic 1 H410
Acute Tox. 4 H302
Skin Irrit. 2 H315
STOT SE 3 H335
STOT SE 3 H336
Aquatic Chronic 2 H411
Skin Sens. 1 H317
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • Ss

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 241 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100 000 - 1 000 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: anti-freeze products, coating products, fillers, putties, plasters, modelling clay, lubricants and greases and finger paints.

Other release to the environment of this substance is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), the low energy manipulation of substances bound in materials or articles, closed, continuous processes with occasional controlled exposure, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, closed batch processing in synthesis or formulation, transfer of chemicals at dedicated facilities, laboratory work, potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens) and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and in processing aids at industrial sites. Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use, outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance can be found in complex articles, with no release intended: vehicles. This substance can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), wood (e.g. floors, furniture, toys), metal (e.g. cutlery, pots, toys, jewellery), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), plastic (e.g. food packaging and storage, toys, mobile phones), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material) and leather (e.g. gloves, shoes, purses, furniture). This substance is intended to be released from scented: paper products.

This substance is used in the following products: inks and toners, fertilisers, coating products, laboratory chemicals, washing & cleaning products, pH regulators and water treatment products, polymers and plant protection products.

This substance is used in the following areas: agriculture, forestry and fishing, building & construction work, printing and recorded media reproduction, health services and scientific research and development. This substance is used for the manufacture of: plastic products and machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, non-industrial spraying, transfer of substance into small containers, roller or brushing applications and treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: washing & cleaning products, perfumes and fragrances, air care products, laboratory chemicals, polishes and waxes, fertilisers, inks and toners, cosmetics and personal care products and coating products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, laboratory work, transfer of substance into small containers, mixing in open batch processes and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: inks and toners, paper chemicals and dyes, textile treatment products and dyes, coating products, washing & cleaning products, non-metal-surface treatment products and polymers.

This substance is used in the following areas: formulation of mixtures and/or re-packaging and mining. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, mixing in open batch processes and roller or brushing applications.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release, for thermoplastic manufacture and as processing aid. Other release to the environment of this substance is likely to occur from: outdoor use as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, laboratory work and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance and formulation of mixtures.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • 3M Deutschland GmbH, Carl-Schurz-Strasse 1 41453 Neuss Germany
  • Access Business Group International BV, Celsiusweg 20 Industrial Estate 4212 5928 PR Venlo Netherlands
  • Active Tools Europe GmbH, Oerlinghauser Straße 65 32107 Bad Salzuflen Germany
  • ADEKA Europe GmbH, Berliner Allee 22 40212 Düsseldorf Germany
  • ADM Services B.V., Kingsfordweg 83 1043 GP Amsterdam Netherlands
  • AGC Chemicals Europe, Ltd., York House Hillhouse FY5 4QD Thornton Cleveleys Lancashire United Kingdom
  • Aldeco Krup,S.L., C/ Doctor Trueta, 183 - 2º 8ª 08005 Barcelona Barcelona Spain
  • ALFARIN QUIMICA, S.A., C/. Ibiza 35 -5º C 28009 MADRID Spain
  • ANNO chemicals N.V., Berkenlaan 21 2980 Halle (Zoersel) (Antwerp) Belgium
  • Anthesis (Ireland) Limited 04, The Black Church St. Mary’s Place D07 P4AX Dublin Ireland
  • ANTWERP DISTILLATION COMPANY NV, GESLECHT PORT 1931 B-9130 KALLO Belgium
  • Archroma Germany GmbH, Kasteler Str. 45 65203 Wiesbaden Germany
  • ARCHROMA IBÉRICA, S.L., ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain
  • ARKEMA PHOTOCURES, 420 rue d'Estienne d'Orves 92700 Colombes France
  • Arrow Regulatory (Ireland) Ltd OR1702, Suite 307, No.9 9 Pembroke Street Upper D02 KR83 Dublin 2 Ireland
  • Arrow Regulatory (Ireland) Ltd OR1705, Suite 307, No.9 9 Pembroke Street Upper D02 KR83 Dublin 2 Ireland
  • Ashland Services BV (OR2), Noordweg 9 3336 LH Zwijndrecht Netherlands
  • B-Lands Consulting (811232-9), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • B.I.G. - OR641, Technische Schoolstraat 43A 2440 Geel Belgium
  • Balchem Italia srl, Via del Porto snc 28040 Marano Ticino NO Italy
  • BASF Coatings GmbH, Glasuritstrasse 1 Postfach 6123 48136 Münster Nordrhein-Westfalen Germany
  • BASF DOW HPPO Production BVBA, Haven 725 / Scheldelaan 600 2040 Antwerpen 4 Belgium
  • BASF Health and Care Products France S.A.S., 49, Avenue Georges Pompidou 92593 Levallois-Perret Cedex France
  • BASF Polyurethanes GmbH, Elastogranstr. 60 49448 Lemförde Niedersachsen Germany
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Bayer AG, Kaiser-Wilhelm-Allee 51373 Leverkusen Germany
  • Beckman Coulter GmbH, Europark Fichtenhain B13 47807 Krefeld Germany
  • British American Tobacco Western Europe Commercial Trading Limited, Regents Park Road Millbrook SO15 8TL Southampton Hampshire United Kingdom
  • C.S.B. GmbH, Duesseldorfer Str.113 47809 Krefeld Germany
  • C.S.B. GmbH, Düsseldorfer Straße 113 47809 Krefeld Germany
  • Celanese Europe BV, The New Atrium Strawinskylaan 3105 1077 ZX Amsterdam Netherlands
  • ChAR Consultancy EOOD, Kırdjali bulvard Bulgaria 37, blok 51 6600 Kırdjali Kırdjali Bulgaria
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited (SHANDONG SHIDA SHENGHUA CHEMICAL GROUP CO.,LTD.), Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED (ZIBO ZHENGDA POLYURETHANE CO., LTD), Room 002, Regus Harcourt Centre HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Dongying Hi-Tech Spring Chemical Industry Co.,Ltd.), Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • Chemours Netherlands B.V., Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • Chemservice GmbH - (7AYP), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • Chemservice S.A. (H5P7), 5, an de Laengten 6776 Grevenmacher Luxembourg
  • Chimcomplex S.A. Borzesti, 3, Industriilor Street 601124 Onesti Bacau Romania
  • CIBA VISION GmbH (OR CVCA), Industriering 1 63868 Großwallstadt Bavaria Germany
  • Clariant Ibérica Producción S.A., Avda. Baix Llobregat, 3-5 08970 Sant Joan Despí Barcelona Spain
  • Clariant Oil Services Scandinavia AS, PB 6054 5892 Bergen Norway
  • Clariant Plastics & Coatings (Deutschland) GmbH, Brüningstrasse 50 65929 Frankfurt am Main Germany
  • Colgate Palmolive Services (Poland) Sp.Zo.o / Mexico, ul. Tasmowa 7 02-677 Warsaw Poland
  • Colgate palmolive Services (Poland) Sp.Zo.o / OR USA, ul. Tasmowa 7 02-677 Warsaw Poland
  • Coloplast Hungary Kft., Búzavirág út 15 2800 Tatabánya Hungary
  • Coreach (Ireland) Ltd, 48 Morehampton Road, Donnybrook Dublin 4 Dublin Ireland
  • COSMETIQUE ACTIVE INTERNATIONAL, 28 rue du Président Wilson 03200 VICHY France
  • Coty Services and Logistics GmbH, Berliner Allee 65 64295 Darmstadt Germany
  • Coty Spain, S.L.U., Calla de la Marina 16-18, piso 16 Torre Mapfre 08005 Barcelona Spain
  • Covestro Deutschland AG, Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany
  • Covestro Deutschland AG OR US_001257, Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany
  • Croda EU B.V. (OR1), Buurtje 1 2802 BE Gouda Netherlands
  • CS Regulatory Ltd 1L-26, The Old Courthouse St Peters Churchyard DE1 1NN Derby United Kingdom
  • CSI-OR001, Pentlands Science Park Penicuik EH26 0PZ Edinburgh United Kingdom
  • CSI-OR003, Pentlands Science Park Penicuik EH26 0PZ Edinburgh United Kingdom
  • CSI-OR011, Pentlands Science Park Penicuik EH26 0PZ Edinburgh United Kingdom
  • CSI-OR016, Pentlands Science Park Penicuik EH26 0PZ Edinburgh United Kingdom
  • DeSangosse Ltd, Hillside Mill Quarry Lane CB25 0LU Swaffham Bulbeck Cambridge United Kingdom
  • Detergenti S.A., Mihai Viteazu street no. 1, Prahova county 106300 Urlati Romania
  • DOW AGROSCIENCES B.V. (BE), Sneeuwbeslaan 20 – bus 10 2610 Wilrijk Belgium
  • DOW AGROSCIENCES ITALIA S.R.L., Via F. Albani 65 20148 Milano Italy
  • DOW AGROSCIENCES LIMITED, CPC2 Capital Park, Fulbourn Cambridge CB21 5XE Cambridgeshire United Kingdom
  • DOW AGROSCIENCES S.A.S., 6 rue Jean-Pierre Timbaud, Immeuble Le Campus, Bâtiment.A 78180 Montigny-le-Bretonneux France
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. - OR1, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. - OR2, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-10, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-5, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-6, Postbus 48 NL-4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR -30, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW DEUTSCHLAND ANLAGENGESELLSCHAFT mbH, Am Kronberger Hang 4 D-65824 Schwalbach Germany
  • Dow Silicones Belgium SPRL OR-1, PSRC - rue Jules Bordet Parc industriel C 7180 Seneffe Belgium
  • Du Pont de Nemours (Deutschland) GmbH, Hugenottenallee 173-175 D-63263 Neu-Isenburg Hesse Germany
  • DuPont de Nemours (Deutschland) GmbH_1, Hugenottenallee 173-175 D-63263 Neu-Isenburg Hesse Germany
  • DuPont Solutions (France) SAS, 22, rue Brunel 75017 Paris France
  • DyStar Colours Distribution GmbH, Am Prime-Parc 12 65479 Raunheim Germany
  • EcoMundo, 215, rue Jean-Jacques Rousseau 92130 Issy-les-Moulineaux France
  • Elementis UK Ltd., Caroline House 55 - 57 High Holborn WC1V 6DX London United Kingdom
  • ENVIGO CRS, S.A.U., Centro Industrial Santiga- Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • Enzymatic Deinking Technologies, BV, Postbus 36, 2040 A A Zandvoort Netherlands
  • Everlight Europe B.V., Rivium Boulevard 112b 2909LK Capelle a/d Ijssel Netherlands
  • Evonik Nutrition & Care GmbH, Rellinghauser Strasse 1-11 45128 Essen Germany
  • Evonik Nutrition & Care GmbH - OR1, Rellinghauser Strasse 1-11 45128 Essen Germany
  • Experien Chemical Services (Europe) Limited, 7 Finkle Street YO7 1DA Thirsk United Kingdom
  • ExponentOR30, The Lenz Hornbeam Park Road HG28RE Harrogate North Yorkshire United Kingdom
  • Faber-Castell AG, Nürnberger Str. 2 90546 Stein Germany
  • FUJIFILM Europe BV, Oudenstaart 1 5047 TK Tilburg Netherlands
  • Fujifilm Imaging Colorants Newcastle, 6th Floor, Acresfield 8-10 Exchange Street M2 7HA Manchester Manchester United Kingdom
  • FujiFilm Manufacturing Europe BV, Oudenstaart 1 5047 TK Tilburg Netherlands
  • Fujimi Europe GmbH, Schlossstrasse 5 D-74653 Ingelfingen Germany
  • GBT Europe GmbH, Sebastianusstraße 10 41460 Neuss NRW Germany
  • Genencor International B.V. - OR-US, Archimedesweg 30 2333 CN Leiden Netherlands
  • GOJO Industries – Europe Ltd., Units 5 & 6 Stratus Park Brinklow MK10 0DE Milton Keynes Buckinghamshire United Kingdom
  • GOVI PRODUCTION COMPANY, Landegemstraat 8 9031 Drongen Belgium
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • HH Compliance, The Rubicon Centre, CIT Campus, Bishopstown, Cork Ireland
  • HH Compliance Ltd., Unit 11D Nutgrove Office Park Nutgrove Avenue 14 Rathfarnham Dublin Ireland
  • HH Compliance Ltd., The Rubicon Building, CIT Campus Bishopstown N/A Cork Ireland
  • HP Deutschland GmbH, Schickardstrasse 32 71034 Boeblingen Germany
  • Huntsman (Europe) BVBA - OR1, Everslaan 45 B-3078 Everberg Belgium
  • HUNTSMAN HOLLAND BV, Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands
  • Huntsman Textile Effects (Germany) GmbH, Rehlinger Str. 1 D-86462 Langweid a.Lech Germany
  • INEOS Composites Hispania S.L. (0341), Partida Povet, 37 ES-12580 Benicarlo Castillon de la Plana Spain
  • INEOS Manufacturing Deutschland GmbH, Alte Strasse 201 50769 Koeln Germany
  • INEOS nv, Haven 1053 -- Nieuwe Weg 1 2070 Zwijndrecht Belgium
  • Infineum Italia, Strada di Scorrimento 2 17047 Vado Ligure (SV) Italy
  • Intechnica Consult GmbH, Ostendstrasse 181 90482 Nuernberg Germany
  • Intertek Deutschland GmbH 1, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH ILUX, Stangenstr.1 70771 Leinfelden- Echterdingen Germany
  • Intertek Deutschland GmbH_KOT, Stangenstrasse 1 70711 Leinfelden-Echterdingen Baden-Wurtemberg Germany
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • INTERTEK FRANCE, ZI ECOPARC II 27400 HEUDEBOUVILLE France
  • Intertoys Holland B.V., Hessenbergweg 8 1101 BT Amsterdam Netherlands
  • John Newlove, Y Berllan Sluvad Road NP4 0SX New Inn, Pontypool United Kingdom
  • JSR Micro n.v., Technologielaan 8 3001 Leuven Belgium
  • JT International Germany GmbH - El Nakhla, Diedenhofener Strasse 20-30 54294 Trier Germany
  • JT International Germany GmbH - FF, Diedenhofener Strasse 20-30 54294 Trier Germany
  • JT International Germany GmbH - JT, Diedenhofener Strasse 20-30 54294 Trier Germany
  • JTI Polska Sp. z o.o., Stary Gostków 42 99-220 Wartkowice Poland
  • Kao Chemicals Europe, S.L. (2), Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain
  • Kemira Oyj, Energiakatu 4 P.O.Box 330 FI-00101 HELSINKI Finland
  • Kerr Dental, Via Passanti 332 84018 Scafati (SA) Italy
  • KH Chemicals B.V., Scheepmakerij 260 3331 MB Zwijndrecht Netherlands
  • knoell Germany - OR - E9, Konrad-Zuse-Ring 25 68163 Mannheim Germany
  • Koopman International B.V., Distelweg 88 1031 HH Amsterdam Netherlands
  • KOSMEPOL Sp. z.o.o., ul. Warszawska 21 05 805 KANIE Poland
  • KTR Europe GmbH, Mergenthalerallee 77 65760 Eschborn Germany
  • L OREAL UK LTD, 255, Hammersmith Road W6 8AZ LONDON United Kingdom
  • L'OREAL, 14 rue Royale 75008 Paris France
  • L'OREAL DEUTSCHLAND GmbH, Herzstrasse 175 D-76187 KARLSRUHE Germany
  • L'OREAL PRODUITS DE LUXE INTERNATIONAL, 106 rue Danton 92300 LEVALLOIS PERRET France
  • L'OREAL SLOVENIJA kozmetika d.o.o., STOZENSKA ULICA 002 1000 LJUBLJANA Slovenia
  • Lamberti Iberia s.a.u., Calle Ceuta 1 - Poligon industrial El Colomer 12200 Onda Castellon Spain
  • Lamberti S.p.A., via Piave 18 21041 Albizzate Varese Italy
  • LASCAD, 7 rue Touzet 93400 Saint Ouen France
  • LCNBV-OR-CXV, Delftseplein 27E 3013 AA Rotterdam Netherlands
  • Lonza Cologne GmbH, Nattermannallee 1 50829 Cologne Germany
  • LTR Industries, Usine Le Mans 72702 Allonnes Cedex France France
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Lubrizol Deutschland GmbH, Max-Planck-Strasse 6 27721 RITTERHUDE Germany
  • Lubrizol Europe Coordination Center BVBA 01, Chaussee De Wavre, 1945 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 02 , Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Limited, The Knowle, Nether Lane Hazelwwod DE56 4AN Derby Derbyshire United Kingdom
  • Lubrizol Luxembourg S.A.R.L, 12 rue Eugène Ruppert 2453 Luxembourg Luxembourg
  • Luxcontrol S.A. (OR51), 1, Avenue des Terres Rouges 4331 Esch-sur-Alzette Luxembourg
  • Lyondell Chemie France S.A.S., Zone Industrielle Portuaire 13270 Fos sur Mer France
  • Lyondell Chemie Nederland B.V., Deltseplein 27E 3013 AA Rotterdam Netherlands
  • Mariner Packaging Company Limited, Estate Road 6 South Humberside Industrial Estate DN31 2TG Grimsby NE Lincs United Kingdom
  • MHM Holding GmbH, Feldkirchener Straße 15 D-85551 Kirchheim Germany
  • Momentive Performance Materials GmbH, Chempark Building V7 51368 Leverkusen NRW Germany
  • NetSun EU B.V., Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands
  • Nouryon Functional Chemicals B.V., Velperweg 76 6824 BM Arnhem Netherlands
  • Nouryon Surface Chemistry AB, Stenunge Allé 3 - S-44485 Stenungsund - Sweden
  • Novozymes A/S, Krogshoejvej 36 2880 Bagsvaerd Denmark
  • Novozymes UK OR1, Novozymes, Brockhurst Davies Ltd 11 The Office Village, North Road, Loughborough LE11 1QJ Loughborough Leicestershire United Kingdom
  • Oleon N.V., Assenedestraat 2 9940 Ertvelde Belgium
  • Oxiteno Europe OR5, Avenue de Tervuren, 273, box 8 1150 Woluwe Saint Pierre Belgium
  • Oy Nizhex Scandinavia Ltd, Wavulinintie 10 00210 HELSINKI Finland
  • Pelikan Vertriebsgesellschaft mbH & Co. KG, Werftstraße 9 30163 Hannover Germany
  • Penman Consulting bvba 02, Avenue des Arts 10 B-1210 Brussels Belgium
  • PHARMEGIC HEALTHCARE LIMITED, Unit 23, Trinity Technology and Enterprise campus, Pearse Street D02WR66 Dublin 2 Ireland
  • Polywater Europe BV, Zuithaven 9-11 Unit B2 4761 CR Zevenbergen Netherlands
  • PPG Europe B.V. - OR3, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • Praxair Surface Technologies GmbH, Am Muehlbach 13 87487 Wiggensbach Germany
  • PRESTIGE ET COLLECTIONS INTERNATIONAL, 16 place Vendôme 75001 PARIS France
  • Procter & Gamble Blois S.A.S., 163/165 quai Aulagnier 92600 ASNIERES SUR SEINE France
  • Procter & Gamble Manufacturing Belgium N.V., Temselaan 100 1853 Strombeek-Bever Belgium
  • Procter & Gamble Manufacturing GmbH, Sulzbacher Strasse 40 65824 Schwalbach am Taunus Germany
  • Procter and Gamble Operations Polska Sp. z o. o., Zabraniecka Street 20 03-872 Warsaw Poland
  • PRODUCTOS CAPILARES L'OREAL S.A., Calle Josefa Valcarcel num. 48 28027 MADRID Spain
  • PURE FISHING Inc, 219 Routede Brignais 69563 Saint Genis Laval France France
  • Ramboll Netherlands B.V., Willem Arntszlaan 115 NL-3734 EE Den Dolder Netherlands
  • REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 B-1040 Brussels Belgium
  • REACH&Colours Kft, Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACHlaw Ltd., Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland
  • REPSOL QUÍMICA, Calle Mendez Alvaro, 44 28045 Madrid Madrid Spain
  • RHODIA OPERATIONS, 40 rue de la Haie Coq 93306 AUBERVILLIERS France
  • RHODIA OPERATIONS - 44, 40 RUE DE LA HAIE COQ 93306 AUBERVILLIERS France
  • Ricardo-AEA, Shoreham Technical Centre Old Shoreham Road BN43 8FG Shoreham West Sussex United Kingdom
  • Robertet, 37 Avenue Sidi Brahim 06131 Grasse France
  • Rotam Crop Protection Europe SAS, 75 cours Albert Thomas-6e avenue/Batiment D 69003 Lyon France
  • RSI ChemRep Europe Ltd (K001), 27-30 Merchants Quay Merchants House 8 Dublin Ireland
  • Saint-Gobain Isover SA, 18 avenue d'Alsace Les Miroirs 92096 La Defense France
  • Shell Chemicals Europe B.V., Weena 70 3012 CM Rotterdam Netherlands
  • SHERWIN-WILLIAMS DIVERSIFIED BRANDS LIMITED, Thorncliffe Park S35 2YP Sheffield Chapeltown United Kingdom
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • SIGMA-ALDRICH CHIMIE SARL, 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France
  • Solenis Netherlands B.V., Fascinatio Boulevard 522 2909 VA CAPELLE A/D IJSSEL Netherlands
  • SOLVAY SOLUTIONS NEDERLAND B.V., ENERGIEWEG 1 4791RN Klundert Netherlands
  • SOLVENTIS EUROPE NV, Sint Maartenstraat 1 B-2000 Antwerpen Belgium
  • SOPROCOS, ZI Le Moulin de tous vents GAUCHY - BP294 02106 SAINT QUENTIN Cedex France
  • SP Automotive GmbH, Viktoriastr. 32-36 56068 Koblenz Germany
  • Specialty Electronic Materials Belgium, BVBA, Sneeuwbeslaan 20 / Pb10 B-2610 Wilrijk Belgium
  • Specialty Electronic Materials Netherlands B.V. OR-4, Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • STERIS Ireland Limited, IDA Business and Technology Park Country Offialy R35 X865 Tullamore Ireland
  • Sucesores de Carmelo Pérez Martínez S.L., Polígono la Unión 3 Ctra. Castellón km 3,7 50013 Zaragoza Spain
  • SUEZ Water Technologies & Solutions Hungary Ltd., Bláthy Ottó u. 4. , P.O. Box 100 2840 Oroszlány Hungary
  • Sun Chemical A/S 7, Københavnsvej 112 4600 Køge Denmark
  • Sun Chemical B.V., Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands
  • Syngenta Hellas AEBE, Anthousas Avenue 153 49 Anthousa-Attiki Greece
  • Syngenta Hellas AEBE, Anthousas Avenue 153 49 Athousa-Attiki Greece
  • TAKASAGO TEG-importer, Industriestrasse 40 D-53909 Zülpich Nordrhein-Westfalen Germany
  • TFL ITALIA SpA, Via dei Campacci 11 20010 Buscate MI Italy
  • THERMACOTE CONSULTING CORP. LTD, PERE TOSHEV 2 2800 SANDANSKI BULGARIA Bulgaria
  • TIGI, Unilever House Springfield Drive KT22 7GR Leatherhead Surrey United Kingdom
  • TSGE_7-3, Concordia House, St. James Business Park Grimbald Crag Court HG5 8QB Knaresborough North Yorkshire United Kingdom
  • Tudo Azul SA, Edifício Espace Alameda dos Oceanos Lote 1.06.1 .4 - Piso 3 - Bloco C 1990-207 Lisbon Portugal
  • UMCO GmbH, Georg-Wilhelm-Straße 187 21107 Hamburg Germany
  • Valmont trading, s.r.o., Nuselská 142/9 140 00 Praha Czech Republic
  • Valspar b.v., Zuiveringweg 89 8243 PE Lelystad Netherlands
  • Versum Materials Netherlands B.V., Kanaalweg 15 PO Box 3193 3502 GD Utrecht Netherlands
  • Vertellus Specialties UK Ltd, Seal Sands Road Seal Sands TS2 1UB Middlesbrough Cleveland United Kingdom
  • Victaulic Europe, Prijkelstraat 36 9810 Nazareth Belgium
  • Vivimed Labs Europe Ltd, PO Box B3 Leeds Road HD1 6BU Huddersfield West Yorkshire United Kingdom
  • Wilkinson Sword GmbH, Schuetzenstr. 110 42659 Solingen NRW Germany
  • Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
  • Zebra A/S, Strandgade 71-73 1401 Copenhagen Denmark
  • [Confidential], [Confidential]
  • DMGO LTD, 82 King Street M2 4WQ Manchester United Kingdom
  • ECOPOL SPA, Via T. Nuvolari, 31 55061 Capannori (LU) Italy
  • Eliane-Green Tech, 15 Wensleydale Road B42 1PR Birmingham West Midlands United Kingdom
  • Henkel Nederland B.V., Brugwal 11 3432 NZ Nieuwegein Netherlands
  • [Confidential], [Confidential]

Other names

  • -
  • 1,2 propylene glycol
  • 1,2-propandiol
  • 1,2-Propane diol
  • 1,2-Propanediol
  • 1,2-Propylene glycol
  • Agent I804
  • Mono Propylen Glycole
  • Mono propylene glyco
  • MONO PROPYLENE GLYCOL
  • monopropilen glicol
  • Monopropylene glycol
  • Monopropylene glycol; MPG
  • Monopropyleneglycol
  • MPG (propane-1,2-diol)
  • propan-1,2-diol
  • Propane-1 ,2-diol
  • Propane-1,2-diol
  • PROPYLENE GLYCOL
  • Propylene glycol - TC0019B
  • Propylene glycol, 1,2-Propanediol
  • propylene glycol 
  • propyleneglycol
  • Propane-1,2-diol
  • (.+-.)-1,2-Propanediol
  • (.+-.)-Propylene glycol
  • (RS)-1,2-Propanediol
  • 1,2-DIHYDROXYPROPANE
  • 1,2-Propandiol
  • 1,2-Propanediol
  • 1,2-Propylene glycol
  • 2-Hydroxypropanol
  • Agent I804
  • CACAO RESINOID 90% PG
  • Methyl ethylene glycol
  • Monopropylene Glycol
  • MPG
  • PG(P)
  • propane-1,2-diol
  • PROPYLENE GLYCOL
  • Propylene glycol (all grades)
  • RADIANOL 4713
  • RADIANOL 4718
  • RADIANOL 4740

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Other (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 4 studies submitted
  • 1 study processed
R Melting / freezing point
-20 °C @ 1.013 hPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 4 studies submitted
  • 1 study processed
R Boiling point
184 °C @ 100.32 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
184 °C

Density

Study results
  • 4 studies submitted
  • 1 study processed
R Relative density
1.03 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.03

Vapour pressure

Study results
  • 3 studies submitted
  • 1 study processed
R Vapour pressure
20 Pa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
20 Pa @ 25 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 1 study processed
R Pow
0.085 @ 20.5 °C and pH 6.2 - 6.4 [1]
R Log Pow
-1.07 @ 20.5 °C and pH 6.2 - 6.4 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
-1.07 @ 20 °C

Water solubility

Study results
  • 3 studies submitted
  • 1 study processed
R Water solubility (vol%)
100 vol% @ 20 °C and pH 7.1 - 7.8 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 1 study processed
R Surface tension
71.6 mN/m @ 1.01 g/L and 21.5 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
71.6 mN/m @ 1 010 mg/L

Flash point

Study results
  • 2 studies submitted
  • 1 study processed
R Flash point
104 °C @ 100.01 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
104 °C

Auto flammability

Study results
  • 2 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
400 °C @ 100.01 - 101.44 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 2 studies submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
7.044 - 43.428 [5]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Study results
  • 2 studies submitted
  • 1 study processed
R Dissipation Half-life (DT50)
2.3 years [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
2.9

Henrys law constant (H)

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Distribution modelling

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 260 mg/L (1)
Intermittent releases (freshwater) 183 mg/L (1)
Marine water 26 mg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 20 g/L (1)
Sediment (freshwater) 572 mg/kg sediment dw (1)
Sediment (marine water) 57.2 mg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 50 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 7 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 40.613 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 5
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
40.613 g/L

Long–term toxicity to fish

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 5 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 18.8 g/L [1]
LC50 (48 h) 18.34 g/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
18.34 g/L
EC50 / LC50 for marine invertebrates
18.8 g/L

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (7 days) 13.02 - 29 g/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
13.02 g/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
EC50 (4 days) 19 - 19.1 g/L [2]
EC50 (72 h) 19.3 - 24.2 g/L [2]
EC50 (48 h) 19 - 34.1 g/L [2]
NOEC (14 days) 5.3 - 15 g/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
19 g/L
EC50 for marine water algae
19.1 g/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (18 h) 20 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
20 g/L

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 168 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 10 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 50 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 10 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Dermal: 40 %
Inhalation: 100 %

Acute toxicity

Study results
oral
  • 3 studies submitted
  • 1 study processed
P/RResults
LD50 22 000 mg/kg bw (rat) [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
dermal
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: respiratory
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 4 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 1 700 - 2 100 mg/kg bw/day [2]
NOAEL (cat): 443 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
NOAEC (rat): 1 - 2.2 mg/L air [2]
LOEC (rat): 160 mg/m³ air [1]

Study data: inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Inhalation route - systemic effects:
Adverse effect observed NOAEC 1 000 mg/m³ (subchronic, rat)
Inhalation route - local effects:
Adverse effect observed LOAEC 160 mg/m³ (subchronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1 2
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study 2
Weight of evidence 3
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant