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Diss Factsheets
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EC number: 618-939-5 | CAS number: 933999-84-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Deviations:
- not specified
- GLP compliance:
- yes
- Type of method:
- HPLC estimation method
- Media:
- other: HPLC mobile phase.
Test material
- Reference substance name:
- 2-({[6-({1-chloro-3-[(oxiran-2-yl)methoxy]propan-2-yl}oxy)hexyl]oxy}methyl)oxirane; 2-[({6-[(oxiran-2-yl)methoxy]hexyl}oxy)methyl]oxirane; 3-chloro-2-({6-[(oxiran-2-yl)methoxy]hexyl}oxy)propan-1-ol; 6-[(oxiran-2-yl)methoxy]hexan-1-ol
- EC Number:
- 618-939-5
- Cas Number:
- 933999-84-9
- Molecular formula:
- C6H14O2 + C3H5ClO
- IUPAC Name:
- 2-({[6-({1-chloro-3-[(oxiran-2-yl)methoxy]propan-2-yl}oxy)hexyl]oxy}methyl)oxirane; 2-[({6-[(oxiran-2-yl)methoxy]hexyl}oxy)methyl]oxirane; 3-chloro-2-({6-[(oxiran-2-yl)methoxy]hexyl}oxy)propan-1-ol; 6-[(oxiran-2-yl)methoxy]hexan-1-ol
- Details on test material:
- As per IUCLID5 Section 1.4.
Constituent 1
- Radiolabelling:
- no
Study design
- Test temperature:
- No data
HPLC method
- Details on study design: HPLC method:
- The High Performance Liquid Chromatography (HPLC) system was fitted with a pulse-free pump and a cyanopropyl resin on silica base column. The mobile phase was methanol/water (55%/45%). The dead time was estimated based on the retention time of an unretained standard. Six reference standards with published Koc values were run on the system to establish the calibration curve data. The curve was calculated as the linear regression line by plotting the logarithm of the capacity factor of the reference conpounds as a function of the respective compound Koc value. Duplicate injections of HDDGE were made. The adsorption coefficient (Koc) of HDDGE was calculated by interpolation of the capacity factor (k) on the calibration cruve.
Batch equilibrium or other method
- Computational methods:
- The adsorption coefficient (Koc) of 1,6-Hexanediol Diglycidylether (HDDGE) was estimated by interpolating the calculated capacity factor (k) of HDDGE on the calibration cruve of the reference substances.
Results and discussion
Adsorption coefficient
- Type:
- Koc
- Value:
- ca. 962
Results: HPLC method
- Details on results (HPLC method):
- The estimated Adsorption Coefficient (Koc) of 1,6-Hexanediol Diglycidylether was 962 and the Log Koc was 2.98.
Applicant's summary and conclusion
- Conclusions:
- The Log Koc for 1,6-Hexanediol Diglycidylether (HDDGE) was approximately 2.98 suggesting low potential for adsorption to soil, sewage sludge and sediment.
- Executive summary:
An estimation of the Log Koc for 1,6-Hexanediol Diglycidylether (HDDGE) was made by an O.E.C.D. Testing Guideline No. 121 study with GLP compliance. The Log Koc for 1,6-Hexanediol Diglycidylether (HDDGE) was approximately 2.98 suggesting low potential for adsorption to soil, sewage sludge and sediment.
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