Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records
Reference
Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 420 (Acute Oral Toxicity - Fixed Dose Method)
GLP compliance:
not specified
Test type:
fixed dose procedure
Limit test:
yes
Species:
mouse
Strain:
not specified
Sex:
not specified
Route of administration:
oral: unspecified
Vehicle:
not specified
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 310 mg/kg bw
Based on:
test mat.
Interpretation of results:
harmful
Remarks:
Migrated information
Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
1 310 mg/kg bw
Quality of whole database:
peer-reviewed

Acute toxicity: via inhalation route

Link to relevant study records
Reference
Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 403 (Acute Inhalation Toxicity)
GLP compliance:
not specified
Test type:
fixed concentration procedure
Limit test:
yes
Species:
rat
Strain:
not specified
Sex:
not specified
Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
not specified
Sex:
not specified
Dose descriptor:
LC50
Effect level:
500 mg/m³ air (nominal)
Based on:
test mat.
Interpretation of results:
harmful
Remarks:
Migrated information
Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LC50
500 mg/m³
Quality of whole database:
peer-reviewed

Additional information

Justification for selection of acute toxicity – oral endpoint

The data is quoted from the journal which is peer-reviewed

Justification for selection of acute toxicity – inhalation endpoint

The data is quoted from the journal which is peer-reviewed

Justification for classification or non-classification