2-Cyclopentene-1-carboxylic acid, 5-(dimethylphenylsilyl)-2-(hydroxymethyl)-, (1R,2R)-2-amino-1,3-dihydroxy-1-(4-nitrophenyl)propyl ester, (1R,5S)-

Guidance on Safe Use

First-aid measures

Emergency measure - Inhalation: If inhaled, provide fresh air, warmth, rest and seek medical

advice.

Emergency measure - Eyes: Wash out eyes thoroughly with plenty of water for fifteen

minutes. If necessary, seek medical advice.

Emergency measure - Skin: Take off contaminated clothing and shoes immediately. Immediately wash contaminated skin with soap and large

quantities of water for fifteen minutes. If necessary, seek

medical advice.

Emergency measure - Ingestion: Do NOT induce vomiting. Drink plenty of water and seek medical advice.

Fire-fighting measures

Recommended extinguishing agent: To suit local surroundings (dry chemical, water spray, foam).

Recommended protective equipment:

Full protective clothing and self-contained breathing apparatus must be worn.                                    

Fight the fire from a safe distance or protected location.  

Product arising from burning: The substance is combustible and will burn if involved in a

fire, evolving noxious fumes (eg carbon, nitrogen and

silicone oxides).

Product determined by test: N

Protective equipment: Full protective clothing and self-contained breathing

apparatus must be worn.

Fight the fire from a safe distance or protected location.

Accidental release measures

Emergency measures in case of spillage: Evacuate personnel from immediate vicinity.  Prevent release to drains and waterways.

Wear appropriate personal protective equipment depending on the nature of the spill.  PPE may include tight fitting safety goggles, lab coat and impervious gloves and respiratory protection.  For larger spills additional protective clothing and equipment such as a self-contained breathing apparatuswith coverall of low permeability may be needed.      

Wet down to avoid dust formation. Absorb spillages of solutions with a suitable inert material (eg. sand or soil).  Contain and collect spillage and place in to waste containers for disposal. Use a sealed industrial vacuum machine (HEPA) or moisten materials to minimize dust generation during pick-up. Clean area wih detergent and water after spill pick-up if appropriate. Dispose of waste material in accordance with local regulations.  

Handling and storage

Handling:  The substance should be stored, handled and used under

conditions of good industrial hygiene and in conformity with

any local regulations in order to avoid exposure. Engineering controls are necessary to reduce exposure to the

substance.

When exposure cannot be prevented or adequately controlled

appropriate personal protective equipment should be worn.

Such protective equipment should conform to the appropriate

international or national standards.

Furthermore, when respiratory protective equipment has to be

used, it must be capable of adequately controlling

exposure, be suitable for the purpose, and conform to the

appropriate international or national standards.

Storage: Store in a cool dry place away from sources of ignition.

Keep containers tightly closed when not in use.

Protect against light.

Packaging of the substance and or preparation: UN approved fibre drums.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

Not classified

Shipping

Labels:

Not applicable

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

Not classified

Shipping

Labels:

Not applicable

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

Not classified

Shipping information

Proper shipping name and description:

Not applicable

Chemical name:

Not applicable

Labels:

Not applicable

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

not classified

Shipping information

Proper shipping name and description:

Not applicable

Chemical name:

Not applicable

Labels:

Not applicable

Remarks

Additional transport information

Additional information

Special provisions / remarks / other:

Transport code: Not classified
Transport: Avoid crushing the containers. In the event of a spillage, observe the warning labels on the container.

Exposure controls / personal protection

Critical points for possible workplace exposure are product charging, sampling, and cleaning and disposal of drums.     Engineering controls in the form of closed transfer systems with local exhaust ventilation are provided during charging. When they are not sufficient to control exposure, approved respiratory protection should be worn.  Respiratory protection should be selected based on exposure potential and according to standard EN 140/EN 136 (half full face respirators), EN 12941/EN12942 (powdered air purifying respirators; loose-fitting/full face) or EN 139 (full face supplied air respirator). For manufacturing areas skin protection should be provided in the form of coveralls (EN 1149-1) or full air suits (EN 465) along with impervious nitrile, rubber or latex gloves (EN374, EN 420). Gloves should be changed regularly and removed after overt contamination.  Chemical safety goggles should be worn if a full-face respirator is not being worn (EN 166).  

Stability and reactivity

Stable under recommended storage conditions.

Danger other than fire: None known.

Chemical reaction with water: None which is hazardous.

Hazardous decomposition products formed under fire conditions: carbon oxides(COx), nitrogen oxides (NOx) and SiOx

Dust explosion: Although material has not been specifically tested, fine

dust suspended in air in sufficient concentration and in the

presence of an ignition source may pose a potential

explosion hazard.  Provide appropriate bonding and grounding

protection to control static charge.  Powder handling

quipment such as dust collectors, dryers, and mills may

require additional protective measures (e.g. explosive

venting).

Disposal considerations

Disposal should be in accordance with applicable regional, national and local laws and regulations.  Disposal by incineration in recommended.

Industry - Possibility of recovery/recycling: Discharge to the environment will be minimal. Recovery from minor spillages or accidental discharge is not  economically or technically feasible, and such waste  material will be disposed of by incineration. In principle, it may be possible to recover larger spillages of uncontaminated material for subsequent use.

Industry - Possibility of neutralisation: The notification tests have shown that the substance is  irritating to the eyes.  No chemical treatment is practicable to neutralise the  hazardous health or hazardous environmental properties.

Industry - Possibility of destruction:

-Controlled discharge: Contaminated containers or spillages of solutions mixed  with inert material (eg. sand or soil) may be disposed of by  incineration in accordance with local regulations.

- Incineration: Incineration is recommended for larger quantities of waste. A closed-cycle incinerator with scrubbers should be employed

- Water purification: Biological oxidation occurs at the waste water treatment plants. Trace quantities are destroyed by biological oxidation in the WWTP on site and trace quantities in aqueous washes can be treated in secondary biological WWTP before discharge to municipal  treatment works. The substance should not normally be  discharged directly to the sewage system or the aqueous environment. However, adverse effects on sewage treatment systems would be unlikely.