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EC number: 278-051-5 | CAS number: 75005-95-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
pH
Administrative data
- Endpoint:
- pH
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 Mar 2020 - 23 Apr 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- CIPAC MT 75 (Determination of pH Values)
- Version / remarks:
- Volume J MT 75.3; 2000
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 122 (Determination of pH, Acidity and Alkalinity)
- Version / remarks:
- 26 July 2013
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7000 (pH)
- Version / remarks:
- August 1996
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-ethylhexyl 2-([1,1'-biphenyl]-4-ylcarbonyl)benzoate
- EC Number:
- 278-051-5
- EC Name:
- 2-ethylhexyl 2-([1,1'-biphenyl]-4-ylcarbonyl)benzoate
- Cas Number:
- 75005-95-7
- Molecular formula:
- C28H30O3
- IUPAC Name:
- 2-ethylhexyl 2-{[1,1'-biphenyl]-4-carbonyl}benzoate
- Test material form:
- liquid
- Details on test material:
- Purity/Composition: 96.27%
Storage Conditions: At room temperature
Test Facility test item number: 210244/A
Test item handling: No specific handling conditions required
CAS number: 75005-95-7
EC Number: 278-051-5
Substance Name: 2-ethylhexyl 2-([1,1'-biphenyl]-4-ylcarbonyl)benzoate
Constituent 1
- Specific details on test material used for the study:
- Physical Description: Colourless to pale yellow liquid (determined by Charles River Den Bosch)
Purity/Composition: 96.27%
Storage Conditions: At room temperature
Purity/Composition correction factor: No correction factor required
Test item handling: No specific handling conditions required
Chemical name: 2-Ethylhexyl 2-([1,1'-biphenyl]-4-ylcarbonyl)benzoate
CAS number: 75005-95-7
EC Number: 278-051-5
Molecular formula: C28H30O3
Molecular weight: 414.22
Reagents
- Reagent:
- other: See below
Titration of acidity and alkalinity
- Details on titrant used:
- Chemicals and Reagents
Text Table 9
Chemicals and Reagents
Chemical / Reagent Supplier
Double distilled water Waldeck, Münster-Roxel, Germany
Potassium hydrogen phthalate (C8H5KO4) Merck, Darmstadt, Germany
Di-sodium tetraborate decahydrate (Na2B4O7.10H2O) Sigma-Aldrich, Steinheim, Germany
0.05M buffer solution pH 4.00 ± 0.02 5.1056 g potassium hydrogen phthalate dried for 2 hours at 105°C, dissolved in double distilled water and made up to 500 mL
0.05M buffer solution pH 9.22 ± 0.02 9.5353 g di-sodium tetraborate decahydrate dissolved in double distilled water and made up to 500 mL
All chemicals and reagents were of analytical grade, unless specified otherwise.
Performance of the Study
The pH of two 1% (w/v) mixtures of the test item in double distilled water was measured using a 906 Titrando (Metrohm, Herisau, Switzerland) and a combined glass electrode (glass glass electrode and reference electrode, Metrohm).
The pH meter was calibrated using a 0.05 M potassium hydrogen phthalate buffer solution (pH 4.00) and a 0.05 M di-sodium tetraborate buffer solution (pH 9.22 at 20°C). At the start and at the end of the measurements, pH of these buffer solutions was measured to ensure proper performance of the pH meter.
For the preparation of the 1% (w/v) mixtures, accurately weighed amounts of 1.0069 g and 1.0015 g of the test item were transferred into a 100 mL measuring cylinder, containing about 50 mL double distilled water. The volume was made up to 100 mL with water, the cylinder was stoppered and the dispersion was shaken vigorously by hand until completely mixed or dispersed. After it was left to stand for 1 minute, the combined glass electrode was immersed into the liquid and the pH was measured without stirring. The pH value was recorded after 1 and 2 minutes. Because the pH value changed more than 0.1 unit during this equilibration time, the pH was also recorded 10 minutes after immersion of the electrode.
The test was performed at 21.5 ± 0.4°C.
Results and discussion
pH value
- pH value:
- 5.8
- Temp.:
- 21.5 °C
- Concentration:
- 1 other: % w/v
Any other information on results incl. tables
The results of the test on the determination of the pH of the test item are given in Table 8.
The 1% (w/v) mixtures of the test item in double distilled water were white turbid suspensions with drops of test item throughout the measuring cylinder.
The pH of the 1% (w/v) aqueous mixtures was 5.8.
Table 8 pH of the Test Item
pH | |
1% (w/v) mixture | |
5.616 | |
5.962 | |
Mean | 5.8 |
Applicant's summary and conclusion
- Conclusions:
- the pH of the substance was determined to be 5.8 under the conditions of the test.
- Executive summary:
Under GLP conditions, the pH of the substance was determined to be 5.8 under the conditions of the test according to guidelines CIPAC MT 75.3, OECD 122 & OPPTS 830.7000.
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