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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1973
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Cross-reference
Reason / purpose for cross-reference:
reference to same study
Reference
Endpoint:
acute toxicity: oral
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Study period:
1973
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
See read-across justification in section 13.2
Reason / purpose for cross-reference:
read-across source
Qualifier:
no guideline followed
Principles of method if other than guideline:
Not specified.
GLP compliance:
no
Remarks:
Test carried out prior to GLP.
Test type:
fixed dose procedure
Limit test:
yes
Species:
other: not specified
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
not specified
Route of administration:
oral: unspecified
Vehicle:
not specified
Details on oral exposure:
not specified
Doses:
not specified
No. of animals per sex per dose:
10
Control animals:
no
Preliminary study:
none
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Based on:
test mat.
Mortality:
No mortality observed
Clinical signs:
other: None observed
Gross pathology:
None observed
Other findings:
see attachment.
Interpretation of results:
GHS criteria not met
Conclusions:
The test substance tested has an acute oral LD50 of > 5.0 g/kg.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1973
Report date:
1973

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Not specified.
GLP compliance:
no
Remarks:
Test carried out prior to GLP.
Test type:
fixed dose procedure
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
3,7-dimethyloctan-1-ol
EC Number:
203-374-5
EC Name:
3,7-dimethyloctan-1-ol
Cas Number:
106-21-8
Molecular formula:
C10H22O
IUPAC Name:
3,7-dimethyloctan-1-ol

Test animals

Species:
other: not specified
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Details on oral exposure:
not specified
Doses:
not specified
No. of animals per sex per dose:
10
Control animals:
no

Results and discussion

Preliminary study:
none
Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Based on:
test mat.
Mortality:
No mortality observed
Clinical signs:
other: None observed
Gross pathology:
None observed
Other findings:
see attachment.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
The test substance tested has an acute oral LD50 of > 5.0 g/kg.