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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17 July 2017 to 26 July 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
not specified
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2008
Deviations:
not specified
GLP compliance:
no
Type of method:
effusion method: vapour pressure balance
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
0.001 Pa
Key result
Test no.:
#3
Temp.:
50 °C
Vapour pressure:
0.029 Pa

Table 1. Results of the effusion method

 Run number

 Temperature (°C)

 Vapour pressure (Pa)

 1

 37

 5.86E-3

 2

 42

 9.95E-3

 3

 47

 1.92E-2

 4  53  4.00E-2
 5  58  7.14E-2
 6  63  1.46E-1
 7  68  2.37E-1

From the measured data points of the vapour pressure curve the constants A and B of the Antoine equation can be derived by regression of the data points to:

A = 15.7691

B = -5593.87

C = 273.15

The vapour pressure of the test item was calculated by interpolation and extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C.

Table 2. Calculated vapour pressure values for 20, 25 and 50 °C

 Temperature (°C)

 Vapour pressure (Pa)

 20

 4.9E-4

 25  1.0E-3
 50  2.9E-2
Conclusions:
The vapour pressure of the test item was determined to be 4.9E-4 Pa at 20°C, 1.0E-3 Pa at 25°C and 2.9E-2 at 50°C.
Executive summary:

The vapour pressure of the test item was measured by the effusion method using a vapour pressure balance. The vapour pressure of the test item was determined to be 4.9E-4 Pa at 20°C, 1.0E-3 Pa at 25°C and 2.9E-2 at 50°C by interpolation and extrapolation of the measured vapour pressure curve. This study is considered to be reliable without restriction (Klimisch 1) as it was conducted according to OECD Guideline 104 and EU Method A.4.

Description of key information

The vapour pressure of the test item was determined to be 4.9E-4 Pa at 20°C, 1.0E-3 Pa at 25°C and 2.9E-2 at 50°C.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
20 °C

Additional information

The vapour pressure of the test item was measured by the effusion method using a vapour pressure balance (2017). The vapour pressure of the test item was determined to be 4.9E-4 Pa at 20°C, 1.0E-3 Pa at 25°C and 2.9E-2 at 50°C by interpolation and extrapolation of the measured vapour pressure curve. This study is considered to be reliable without restriction (Klimisch 1) as it was conducted according to OECD Guideline 104 and EU Method A.4.