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Diss Factsheets
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EC number: 618-095-8 | CAS number: 879-57-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Deviations:
- no
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- Type: mixed population of aquatic microorganisms (activated sludge)
Origin: aeration tank of a waste water plant treating predominantly domestic sewage (Kläranlage Odenthal)
Date of collection: 2000-01-17
Pretreatment: none
Concentration of inoculum: 30 mg/L SS - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Details on study design:
- Pretreatment of the test substance:
- 25 mg test substance were weighed out and added to the test vessels to give a test concentration of 100 mg/L test substance
Exposure conditions:
- Test volume : 250 ml, Mixing: 1 magnetic stirrer per test vessel, Incubation temperature : 22 +- 1 °C
- Tests with reference compound, sodium bezoate, were run in parallel (100 mg/L)
- toxicity control (reference compound, test item, inoculum) and blank control without test item was carried out
- Test substance, blank control and reference compund were run in triplicates, toxicity control in duplett
- pH value of the test vessels at the end of the test: 7.6 - Reference substance:
- benzoic acid, sodium salt
- Remarks:
- purity 99 %
- Parameter:
- % degradation (O2 consumption)
- Value:
- 5
- Sampling time:
- 28 d
- Details on results:
- The used concentrations of Imidoxim did not show toxic effects to bacteria.
- Results with reference substance:
- The reference compound sodium benzoate showed 84 % degradation after 28 days.
- Validity criteria fulfilled:
- yes
- Remarks:
- biodegradation of reference compound >= 60 % within 14 days; in the toxicity control degradation rates > 25 % within 14 days; replicates difference < 20 %; oxygen uptake of blank inoculum <= 60mg/L; no pH influence
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- Within 28 days, a degradation of 5 % was determined for Imidoxim and thus it has to be classified as "Not Readily Biodegradable".
- Executive summary:
A study was performed to assess the ready biodegradability of Imidoxim and was conducted in accordance with the Council Directive 92/69/EEC Method C.4-D "Manometric Respirometry Test" which is in most parts equivalent to the OECD Guideline for Testing of Chemicals No. 301 F "Manometric Respirometry Test". A measured volume of inoculated mineral medium, containing a known concentration of test chemical 100 mg/L of the test substance, to give at least 50-100 mg ThOD/litre as the nominal sole source of organic carbon, is stirred in a closed flask at a constant temperature (+- 1°C) for up to 28 days. The consumption of oxygen is determined by measuring the quantity of oxygen (produced electrolytically) required to maintain constant gas volume in the respirometer flask. The amount of oxygen taken up by the test chemical (corrected for uptake by blank inoculum, run in parallel) is expressed as a percentage of theoretical oxygen demand (ThOD) or chemical oxygen demand (COD). Imidoxim showed 5 % degradation and the reference compound showed 84 % degradation after 28 days. As the toxicity control showed a degradation of 44 % after 28 days it can be concluded that the used concentration of Imidoxim is not toxic to bacteria. Therefore Imidoxim has to be classified as "Not Readily Biodegradable".
Reference
Description of key information
A study was performed to assess the ready biodegradability of Imidoxim and was conducted in accordance with the Council Directive 92/69/EEC Method C.4-D "Manometric Respirometry Test".
Within 28 days, a degradation of 5 % was determined for Imidoxim and thus it has to be classified as "Not Readily Biodegradable".
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The toxicity control showed a degradation of 44 % leading to the conclusion that the used concentration of Imidoxim is not toxic to bacteria.
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