Registration Dossier
Registration Dossier
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EC number: 435-740-7 | CAS number: 94317-64-3
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
Justification for classification or non-classification
NBPT produced evidence of skin sensitization in 13% of the animals (2 of 15) at the challenge reading. While the number of animals studied is lower than the 20 recommended by OECD Guideline 406, the study is well documented and reliable. It is highly unlikely that additional animals would increase the number of animals with positive responses to 30% or greater. Based upon this information, the criteria for classification as a dermal sensitizer according to CLP are not met.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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