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EC number: 248-363-6
CAS number: 27247-96-7
Cumulated recovery data (% applied dose) after application of 1 g/kg
[14C] 2-EH in female rats for 6h
*: lowest limit, due to non-sampled
skin/organs/blood/carcass (absorbed) and stratum corneum
**: total of all lines above (absorbed, non-absorbed,
***: min: total absorbed; max: 100 - total non absorbed
Based on a study in female rats treated dermally at 1 g/kg with adequate
occlusion and limitation of evaporation, 2EH was characterized by:
- a dermal absorption of 5.7 to 14.6% of the applied dose; however this
may be underestimated due to 8-fold higher applied amount vs. guideline
- an indicative dermal absorption rate (assuming a constant rate over
exposure period) of 0.63 to 1.61 mg/cm2/h.
Ranges depend whether non-recovered radioactivity and cage wash were
considered as absorbed or not.
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