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Toxicity to microorganisms

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Description of key information

The respiration inhibition of alphamethylstyrene was investigated in a study conducted according to EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test) and OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test). The 3 h EC10, EC20, EC50, and EC100 were determined to be 661.5, 998.7, >2000, and >2000, respectively. 

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
661.5 mg/L

Additional information

Reliable results obtained in a guideline study are available. The respiration inhibition of alphamethylstyrene was investigated in a study conducted according to EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test) and OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test). The 3 h EC10, EC20, EC50, and EC100 were determined to be 661.5, 998.7, >2000, and >2000, respectively. The validity criteria were fulfilled (reference substance: sensitivity of the activated sludge was in the accepted range; individual respiration rates of the blanks were within 15% of each other).