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EC number: 200-820-0
CAS number: 74-89-5
The data of irritation potential of
methylamine are waived from the acute toxicity studies (see 7.2.1. Acute
toxicity oral, BASF-Test and 7.2.2. Acute toxicity inhalation,
BASF-Test, Acute toxicity dermal: Goffman and Maguire, 1980).
Monomethylamine caused eye, nose and throat
irritation if inhaled. Administered orally to the rats, methylamine was
corrosive to stomach. Liquefied methylamine (or in contact with moist
skin) caused necrosis in the guinea pigs skin which was evident for
histological evaluation after 48 hours. In
concentrations of 141 ppm a 50 % decrease of the respiratory rate in
rats was found (Gagnaire etal., 1989).
Effects on skin
Effects on eye irritation: corrosive
Effects on respiratory irritation: irritating
Classification & Labeling:
Monomethylamine (aqueous solution) is
classified according to GHS as: Skin Corr. 1B, H314: Causes severe skin burns
and eye damage
Monomethylamine (gaseous form) is classified
according to GHS as: Skin Irrit. 2 , Eye damage 1, H315: Causes skin irritation,
H318: Causes serious eye damage
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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