Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 248-666-3 | CAS number: 27813-02-1
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only summary of the studies available. No details.
Data source
Reference
- Title:
- No information
- Author:
- Rohm & Haas, personal communication (1994), unpublished|report, Rohm & Haas, No. 91RC-197B (1991)
Materials and methods
- Type of study / information:
- Type: adsorption
Test material
Results and discussion
Any other information on results incl. tables
Dermal absorption was studied in male rats receiving 50 ul
of a 2000 ppm solution of 14C HPMA in engine oil. Exposure
time was 8 hours.
Result:
Total recovery of 14C: 81 %. 56 % evaporated from the dosing
site. The amount absorbed was determined to be 29 % of the
radioactivity. Radioactivity was observed in the skin (7 %),
carcass (2 %), urine (1 %), faeces (< 1 %) and as volatile
organics (< 1 %).
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
