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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Hemolysis of erythrocytes by anitbacterial preservatives
Author:
Ansel HC, Cadwallader DE.:
Year:
1964
Bibliographic source:
J. Pharm. Sci. 53, 169-172
Reference Type:
other: abstract
Title:
Hemolytic effect of benzyl alcohol
Author:
McOrmond P, Gulck B, Duggan HE, Hopper J
Year:
1980
Bibliographic source:
Drug Intell. Clin. Pharm. 14, 549

Materials and methods

Type of study / information:
in vitro
Principles of method if other than guideline:
fresh blood from rabbits and healthy donors were incubalted with the testsubstance in vitro in the presence of 0.9 % MaCl
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzyl alcohol
EC Number:
202-859-9
EC Name:
Benzyl alcohol
Cas Number:
100-51-6
Molecular formula:
C7H8O
IUPAC Name:
phenylmethanol
Details on test material:
no further data

Results and discussion

Any other information on results incl. tables

RM-Freetext:
Benzyl alcohol can cause hemolysis of human and rabbit
erythrocytes in the presence of 0.9 % NaCl.

Applicant's summary and conclusion