Registration Dossier

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

Additional information

 The results of the physico-chemical properties of 4,4’-Methylene bis (2-chloroaniline) (CAS no: 101-14-4, EC no: 202-918-9) are given below.

Endpoint

Guideline(s)

Result

Comments

Appearance/physical state/colour

No guideline followed

 

Regulation (EC) No. 1907/2006

Light yellow granular solid

 

Yellow pellets with amine odor

Visual examination at testing lab

 

Company MSDS

Melting point

OECD Guideline 102

EU Method A.1

The melting temperature of 4,4’-Methylene bis (2-chloroaniline) was determined using DSC. The melting temperature of the substance is 101.3 °C.

Differential scanning calorimetry

Boiling point

OECD Guideline 103

EU Method A.2

Boiling was not observed before the decomposition temperature (> 370 degr C)

Test waived

Density

OECD Guideline 103

Density at 15 degr C: 1440 kg/m3

Substance was melted and volume pycnometer was used

Particle size distribution (Granulometry)

OECD Guideline 110

99.5% of the pellets are >2000 μm 

Vapour pressure

OECD Guideline 103

EU Method A.2

< 1.47 x 10E-3 Pa = < 1.10 x 10E-5 mm Hg at 20˚C (293K)

isothermal thermogravimetric effusion method

Partition coefficient

OECD Guideline 117

EU Method A.8

4,4’-Methylene bis (2-chloroaniline)

Log Pow: 2.50

Pow: 3.16 x 10e+2

Impurity > 1% (peak area):

Log Pow: 3.73

Pow: 5.37 x 10e+3

HPLC method

Water solubility

OECD Guideline 105

EU Method A.6

The water solubility of 4,4’-Methylene bis (2-chloroaniline) at 20°C was 1.38 x 10E-2 g/l. The pH of the aqueous samples after 240 hours stirring was 7.6.

flask method, results were obtained after 240 hour stirring

Surface tension

OECD Guideline 105

EU Method A.6

The surface tension of a test solution at 90% of the test substance saturation solubility in water and at 20°C was 73.3 mN/m. According to this, the test substance is considered not to be surface active.

OECD harmonised ring method

Flash point

OECD Guideline 105

EU Method A.6

 

Test waived

Auto flammability

United Nations (UN), UN no.ST/SG/AC.10/11/Rev.4: Recommendations on the Transport of Dangerous Goods, Part: Classification Procedures, Test Methods and Criteria Relating to Explosives of Class 3, Class 4, Division 5.1 and Class 9, Test N.4: “Test Method for Self-heating Substances”, 2003

 

Test waived

 

Flammability

EU Method A.10

United Nations (UN), UN no.ST/SG/AC.10/11/Rev.4: Recommendations on the Transport of Dangerous Goods, Part III: Classification Procedures, Test Methods and Criteria Relating to Explosives of Class 3, Class 4, Division 5.1 and Class 9, Test N.1, 2003.

The preliminary screening test was performed for the determination of the flammability of 4,4’-Methylene bis (2-chloroaniline). Based on the results obtained, the test substance is considered ‘not highly flammable’.

 

Flammability (Contact with water)

EU Method A.12

UN no.ST/SG/AC.10/11/Rev.4: Part III, Test N5, 2003

UN no.ST/SG/AC.10/11/Rev.4: Appendix 6, Screening procedures, 2003

Based on the evaluation of structural features, 4,4’-Methylene bis (2-chloroaniline) is considered ‘not highly flammable’ in contact with water.

 

statement

Pyrophoric Properties of Solids and Liquids

EU Method A.13

UN no.ST/SG/AC.10/11/Rev.4: Part III, Test N2, 2003

UN no.ST/SG/AC.10/11/Rev.4: Appendix 6, Screening procedures, 2003

Based on the evaluation of structural features, 4,4’-Methylene bis (2-chloroaniline) has no pyrophoric properties.

statement

Explosiveness

EU Method A.14

Based on the evaluation of the chemical structure and oxygen balance value of 4,4’-Methylene bis (2-chloroaniline), it is deemed not to be potentially explosive.

statement

Oxidizing properties

EU Method A.17

Based on the evaluation of the chemical structure and oxygen balance value of 4,4’-Methylene bis (2-chloroaniline), it is deemed not to be potentially oxidizing.

statement

Stability in organic solvents

 

 

Test waived

Dissociation constant

 

 

Test waived

Viscosity

 

 

Test waived