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EC number: 205-746-2
CAS number: 149-74-6
Dichloro(methyl)(phenyl)silane is a chlorosilane, generating hydrogen
chloride in the presence of moisture, it is expected to be corrosive.
Therefore, in accordance with Column 2 of REACH Annexes VII and VIII,
the in vitro and in vivo skin and eye irritation studies (required in
Section 8.1.1 and 8.2.1) do not need to be conducted as the available
information indicates that the substance meets the criteria for
classification as corrosive to skin. The limited experimental data
available on skin and eye irritation/corrosion ( Dow Corning
Corporation, 1969 for both studies) support the above comments on the
potentially corrosive nature of this material.
hydrolyses rapidly in contact with water and moist air, releasing
two moles of hydrogen chloride (HCl) for each mole of parent material.
Although the irritation/corrosion studies available are limited, their
findings support the severe skin, eye and respiratory damage that would
be expected due to release of HCl.
is classified 'Skin Corr. 1A', with hazard statement H314 'Causes
severe skin burns and eye damage' according to
Regulation (EC) No 1272/2008.
additional hazard statement 'EUH071 Corrosive to the respiratory tract'
(1272/2008/EC) is applied, in accordance with related chlorosilane
substances and the findings of a limited acute inhalation study, and
based on the expected respiratory tract damage caused by the hydrolysis
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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