Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report Date:
2009

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Version / remarks:
EU Method A.8 (Partition Coefficient)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
> 6.5
Temp.:
25 °C
pH:
ca. 6.4
Details on results:
Reference substances used: Log Pow
2-Butanone 0.3
Acetanilidine 1.0
Cinnamyl alcohol 1.9
2,6-Dichlorobenzonitrile 2.6
Allyl phenyl ether 2.9
Benzophenone 3.2
Isopropylbenzene 3.7
Diphenyl ether 4.2
Fluoroanthene 5.1
DDT 6.5

Applicant's summary and conclusion

Conclusions:
log Pow > 6.5 (at 25°C; HPLC method)