Registration Dossier

Classification & Labelling & PBT assessment

GHS

General Information

Not classified
Implementation:
EU
Remarks:
Rationale for testing the substance as aqueous solution
The testing laboratory got the substance as an aqueous solution. The testing of the product in pure form is not practicable for the reasons set out below:
The product is obtained in the form of an aqueous solution containing active ingredient and sodium chloride. The manufacturing at higher contents of solids is not possible, because otherwise the solubility of the reactant sodium monochloroacetate is exceeded and no complete conversion to the registration substance is achieved.
The following attempts were made in the laboratory to isolate the substance from the aqueous solution:
To purify the product (partial desalination) the water was distilled in vacuum at elevated temperature. The substance was present as a highly viscous liquid, which solidified on cooling to a tough, glassy mass. Therefore, the product was dissolved in ethanol at elevated temperature. During cooling in refrigerator sodium chloride crystallized and could be separated by filtration. By this, sodium chloride content can be reduced to 9% of the solids content. The ethanol was distilled under vacuum at elevated temperature, and the product was left as highly viscous liquid.
The product in this form (91% active, 9% sodium chloride) solidified at room temperature to a tough, glass-like mass that could not be handled (poured, weighed, crushed, ...) or brought back into solution. An application or processing in this form is not possible. In addition, this substance is highly hygroscopic. For this reason, the hot substance was diluted with water thus converted into an easily manageable, liquid form. At higher solids content, the solution changes during time (formation of precipitates, turbidity) and by this a uniform composition over time cannot be guaranteed.
Conclusion
Thus the physical form oft the substance submitted for testing (aqueous solution) is the highest technically feasible active ingredient content concentration. It contains additional substances as water and sodium chloride. The concentration oft commercially marketed products, now and in future, for the reasons given above, doesn’t exceed this concentration.

Related composition

Related composition:
Composition 1

Classificationopen allclose all

Explosives
Reason for no classification:
conclusive but not sufficient for classification
Flammable gases and chemically unstable gases
Reason for no classification:
conclusive but not sufficient for classification
Aerosols
Reason for no classification:
conclusive but not sufficient for classification
Oxidising gases
Reason for no classification:
conclusive but not sufficient for classification
Gases under pressure
Reason for no classification:
conclusive but not sufficient for classification
Flammable liquids
Reason for no classification:
conclusive but not sufficient for classification
Flammable solids
Reason for no classification:
conclusive but not sufficient for classification
Self-reactive substances and mixtures
Reason for no classification:
conclusive but not sufficient for classification
Pyrophoric liquids
Reason for no classification:
conclusive but not sufficient for classification
Pyrophoric solids
Reason for no classification:
conclusive but not sufficient for classification
Self-heating substances and mixtures
Reason for no classification:
conclusive but not sufficient for classification
Substances and mixtures which in contact with water emit flammable gases
Reason for no classification:
conclusive but not sufficient for classification
Oxidising liquids
Reason for no classification:
conclusive but not sufficient for classification
Oxidising solids
Reason for no classification:
conclusive but not sufficient for classification
Organic peroxides
Reason for no classification:
conclusive but not sufficient for classification
Corrosive to metals
Reason for no classification:
data lacking
Desensitized explosives
Reason for no classification:
data lacking
Acute toxicity - oral
Reason for no classification:
conclusive but not sufficient for classification
Acute toxicity - dermal
Reason for no classification:
conclusive but not sufficient for classification
Acute toxicity - inhalation
Reason for no classification:
data lacking
Skin corrosion / irritation
Reason for no classification:
conclusive but not sufficient for classification
Serious eye damage / eye irritation
Reason for no classification:
conclusive but not sufficient for classification
Respiratory sensitisation
Reason for no classification:
data lacking
Skin sensitisation
Reason for no classification:
conclusive but not sufficient for classification
Aspiration hazard
Reason for no classification:
data lacking
Reproductive toxicity
Reason for no classification:
conclusive but not sufficient for classification
Effects on or via lactation
Reason for no classification:
data lacking
Germ cell mutagenicity
Reason for no classification:
conclusive but not sufficient for classification
Carcinogenicity
Reason for no classification:
data lacking
1. Specific target organ toxicity - single
Reason for no classification:
conclusive but not sufficient for classification
1. Specific target organ toxicity - repeated
Reason for no classification:
conclusive but not sufficient for classification
Hazardous to the aquatic environment (acute / short-term)
Reason for no classification:
conclusive but not sufficient for classification
Hazardous to the aquatic environment (long-term)
Reason for no classification:
data lacking
Hazardous to the ozone layer
Reason for no classification:
data lacking

Labelling

Signal word:
No signal word

Notes