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Ecotoxicological information

Long-term toxicity to fish

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Reference
Endpoint:
long-term toxicity to fish, other
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from computational model developed by USEPA
Qualifier:
according to
Guideline:
other: Modelling database
Principles of method if other than guideline:
Long term toxicity to fish was carried out according to the ECOSAR version 1.11
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
other: Fish
Test type:
flow-through
Water media type:
freshwater
Total exposure duration:
28 d
Reference substance (positive control):
no
Key result
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
69.556 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Neutral Organic SAR
Validity criteria fulfilled:
no
Conclusions:
On the basis of effects observed in a freshwater system, the NOEC value for the substance is estimated to be 69.556 mg/l for fish for 28 days of exposure duration
Executive summary:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance . On the basis of effects observed in a freshwater system, the NOEC value for the substance is estimated to be 69.556 mg/l for fish for 28 days of exposure duration., it can be concluded that the test chemical can be considered as non-toxic to fish at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria. 

Description of key information

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance. On the basis of effects observed in a freshwater system, the NOEC value for the substance is estimated to be 69.556 mg/l for fish for 28 days of exposure duration., it can be concluded that the test chemical can be considered as non-toxic to fish at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria. 

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
69.556 mg/L

Additional information

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance. On the basis of effects observed in a freshwater system, the NOEC value for the substance is estimated to be 69.556 mg/l for fish for 28 days of exposure duration., it can be concluded that the test chemical can be considered as non-toxic to fish at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.