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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
January 24, 2012 - March 19, 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
(1995)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
(2008)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
Version / remarks:
(1998)
Deviations:
no
GLP compliance:
yes
Type of method:
other: visual observation
Key result
Water solubility:
>= 206.4 - < 1 032 g/L
Temp.:
20.5 °C
Remarks on result:
other: The pH was not measured.
Details on results:
- 0.1 ml water was added to 0.1032 g test substance resulting in a nominal concentration of 1032 g/l. The solution was shaken for 10 minutes after which the test substances appeared not to be dissolved.
- Additionally, 0.4 ml water was added making a total volume of 0.5 ml water, resulting in a nominal concentration of 206.4 g/l. The solution was shaken for 10 minutes after which the test substance appeared to be completely dissolved.
Conclusions:
The water solubility of the substance has been determined by visual observation in accordance with OECD 105 (1995), EU Method A.6 (2008), EPA OPPTS 830.7840 (1998) and according to GLP principles. The water solubility of the substance is between 206.4 g/l and 1032 g/l at 20.5°C.

Description of key information

 The water solubility of the substance was determined to be between 206.4 g/l and 1032 g/l at 20.5°C. The critical micelle concentrations of two substances representative for the registered substance were determined to be 239.3 and 262 mg solids/L.

Key value for chemical safety assessment

Water solubility:
206.4 g/L
at the temperature of:
20 °C

Additional information

The water solubility of the substance has been determined by visual observation in accordance with OECD 105 (1995), EU Method A.6 (2008), EPA OPPTS 830.7840 (1998) and according to GLP principles. In addition, the critical micelle concentration was determined for two substances representative for the registered substances by measuring the surface tension of solutions at eight different substance concentrations according to a method based on ISO 4311. The critical micelle concentrations of the two substances were determined to be 239.3 and 262 mg solids/L.