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EC number: 221-416-0 | CAS number: 3088-31-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
A 96 h study was conducted for Sodium 2-(2-dodecyloxyethoxy) ethyl sulphate on Danio rerio, at a test concentration of 12.5mg/L, 25 mg/L, 50 mg/L, 75 mg/L & 100 mg/L. Based on nominal concentrations, the median lethal concentration LC50 (96 h) for Sodium 2-(2-dodecyloxyethoxy) ethyl sulphate on Danio rerio was found to be 25 mg/L. But the BCF value of Sodium 2-(2-dodecyloxyethoxy) ethyl sulphate reported was not >= 2000 as well as the substance was found to be rapidly degradable. Thus,considering the CLP Criteria for aquatic classification of the substance , it is concluded that sodium 2-(2-dodecyloxyethoxy) ethyl sulphate does not exhibit short term toxicity to fish [Danio rerio].
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 25 mg/L
Additional information
Based on the various studies available with Klimish rating 2 for the target substance CAS NO 3088-31-1 and read across substances and based on the category approach of organic functional group along with similar mechanistic approach and having structural similarities defined by QSAR toolbox. The results is summarized as follows
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Remarks |
1 |
LC50 |
25 mg/l |
mortality |
96 hrs |
Danio rerio |
Study Report for target chemical |
2 |
LC50 |
102.59 mg/l |
mortality |
96 hrs |
Danio rerio |
Predicted data for target chemical |
3 |
LC50 |
46 mg/l |
mortality |
48 hrs |
Oryzias latipes |
Data from publication for CAS NO 151-21-3 |
By applying weight of evidence approach to the studies summarized in the above table it can be observed that the LC50 values was found to be in range of 25 to 102.59mg/l in 96 hrs and 48 hrs on the basis of mortality effect . But the BCF value ofSodium 2-(2-dodecyloxyethoxy) ethyl sulphatereported was not >= 2000 as well as the substance was found to be rapidly degradable. Thus considering the CLP Criteria for aquatic classification of the substance, it is concluded that Sodium 2-(2-dodecyloxyethoxy) ethyl sulphate does not exhibit short term toxicity to fish (Oryzias latipes,Danio rerio)
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