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EC number: 249-044-4
CAS number: 28472-97-1
The PBT Assessment for Diisodecyl azelate (CAS 28472-97-1) is
based on the criteria set out in the “Guidance on information
requirements and chemical safety assessment, Chapter R.11: PBT
Assessment” (ECHA, 2014).
Diisodecyl azelate (CAS 28472-97-1) is readily biodegradable.
Thus, the test substance does not meet the screening criterion for
persistence and it is not considered to be P or vP.
The bioaccumulation potential of Diisodecyl azelate (CAS
28472-97-1) is expected to be low.This assumption is based on a
low bioavailability of the substance due to its ready biodegradability
and low water solubility. Furthermore the substance is rapidly
metabolised and excreted by organisms and thus an accumulation is not
expected. This is supported by calculated low BCF/BAF values (BCF/BAF:
0.9/1.1 L/kg; Arnot-Gobas estimate, upper trophic). Thus, the substance
does not meet the screening criterion for bioaccumulation and is not
considered to be B or vB.
Diisodecyl azelate (CAS 28472-97-1) is considered as not toxic. In
a chronic study with Daphnia magna a NOELR (21 d) of 4 mg/L (nominal, >
water solubility) based on reproduction was recorded which is above the
trigger value of 0.01 mg/L. Furthermore the substance is not
classified according to Regulation (EC) No. 1272/2008 (7th ATP). Thus,
the criteria set out in Annex XIII of Regulation (EC) No. 1907/2006 are
not met and the substance is considered to be not T.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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