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EC number: 221-264-5
CAS number: 3049-71-6
The test substance is with high probability acutely not harmful to
The inhibition of the degradation activity of activated sludge is not
anticipated when introduced in appropriate low concentrations.
The test substance belongs to the category of perylene as indicated by
its chemical core structure. Based on this structure and the chemical
and biological stability of perylenes under environmental conditions,
data from structural analogue perylenes can be used to cover this
endpoint required under REACh if no data for the original test substance
In a GLP study following OECD guideline 203 the acute toxicity of the
analogue perylene CAS 4948-15-6 to fish was determined. Test fish of the
species Brachydanio rerio were exposed to the substance for 96
hours in a static test system. At test termination a LC50 > 1350 mg/L
based on measured test substance concentrations was determined [BASF AG,
A study on the toxicity of the analogue substance CAS 81-33-4 to Daphnia
magna has been conducted according to OECD guideline 202 following a
static test system setup [BASF SE, 2012]. At test termination after 48 h
no toxicity was observed up to the limit of solubility of the test
substance (EC50 > 0.0065 mg/L; measured).
The acute toxicity of the test substance to aquatic invertebrates
has been examined in a GLP guideline study according to EEC Directive
92/32/EEC. The test animals of the species Daphnia magna were exposed to
the test substance for 48 h in a static test system set up. At test
termination an EC50 > 100 mg/l was determined [BASF AG, 1998]. Similar
results were obtained for Perylen Schwarz/Black I (EC 479-300-2) and
Perylen Schwarz/Black II (EC 475-310-6) were toxicity to Daphnia magna
was examined in 48 hour static limit tests according to OECD guideline
202, respectively. At test termination an EC50 of > 100 mg/l based on
nominal test substance concentrations was determined, respectively (BASF
AG 2005, 2006).
The toxicity of the analogue substance CAS 4948-15-6 on aquatic algae
was investigated in a GLP guideline study according to OECD 201 with Pseudokirchneriella
subcapitata [BASF SE, 2012]. The substance had no observable
inhibitory effect on algae growth up to its saturation limit in the test
media and under test conditions. The ErC50 value after 72 h of exposure
was determined to be > 100 mg/L (nominal). The inhibiting
abilities of Perylen Schwarz/Black I (EC 479-300-2) and Perylen
Schwarz/Black II (EC 475-310-6) to Pseudokirchnerella subcapitata were
examined in GLP studies according to OECD guideline 201, respectively.
After 72 h the EC50 value for Perylen Schwarz/Black I and Perylen
Schwarz/Black II was determined to be > 100 mg/L based on the nominal
concentration of the test substances (BASF AG 2006). No effect was
observed up to the solubility limit of the test substance in water.
The acute toxicity of the analogue substance CAS 81-33-4 to aquatic
plants has been examined in a GLP guideline study according to OECD 221
with the test species Lemna gibba [BASF SE, 2012]. At test
termination after 7 d, an ECr50 > 0.007 mg/L (measured) relating to
growth rate (frond rate and dry weight, respectively) was determined.
Oxygen consumption test which were conducted according to ROBRA
(DIN 38412, part 27) within bacteria Pseudomonas putida was exposed to
different test concentrations of the test substance [BASF AG 1990].
After an exposure period of 30 minutes the lowest determined effect
concentration was > 10000 mg/L (nominal).
All tests were run with concentrations above the water solubility
of the test substance and its analogues, respectively. Thus, no effects
in the range of the water solubility of the substance were determined.
The hazard assessment of the substance reveals neither a need to
classify the substance as dangerous to the environment, nor is it a PBT
or vPvB substance, nor are there any further indications that the
substance may be hazardous to the environment. Therefore, and for
reasons of animal welfare long-term toxicity testing in fish and aquatic
invertebrates is not provided.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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