Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Readily biodegradable (101.63 % degradation after 28 days), OECD 301 B, McLaughlin 2012

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

The ready biodegradability of the test material was determined in a GLP study which was conducted in accordance with the standardised guideline OCED 301 B in a CO2evolution test.

 

The mean cumulative net percent CO2evolved (percent biodegradation) from the aqueous test medium fortified with test material at 10 mg C/L was 101.63 % on day 28. The toxicity control on day 3 was 28.41 %, which indicates that the test material was not toxic to the inoculum in the test medium.

 

The cumulative net percent CO2evolved from the sodium benzoate procedural control was 67.48 % of theoretical by day 7, thus meeting the “pass” criteria of the test (reaching 60 % or greater CO2evolution within a 10-day window of reaching 10 % biodegradation). This rapid biodegradation of sodium benzoate confirmed the presence of an active microbial population and system integrity.

Under the conditions of the study the test material was determined to be ‘readily biodegradable’ (reaching 60 % or greater CO2 evolution within a 10-day window of exceeding 10 % biodegradation).

The study was performed in line with GLP and an accepted standardised guideline with a high standard of reporting. The study was assigned a reliability score of 1 and considered suitable for assessment as an accurate reflection of the substance.

The available data are considered to be complete and the conclusion, readily biodegradable, was taken forward for risk assessment.

No further degradation studies are required.