Registration Dossier

Administrative data

Endpoint:
basic toxicokinetics
Type of information:
other: toxicokinetics assessment
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The assessment of the toxicokinetics of NDI is based on physico-chemical properties of the compound and on toxicological data. Experimental toxicokinetic studies were not performed.

Data source

Reference
Reference Type:
other: Toxicokinetics Assessment
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Principles of method if other than guideline:
assessment on toxicokinetics

Test material

Constituent 1
Chemical structure
Reference substance name:
1,5-naphthylene diisocyanate
EC Number:
221-641-4
EC Name:
1,5-naphthylene diisocyanate
Cas Number:
3173-72-6
Molecular formula:
C12H6N2O2
IUPAC Name:
1,5-diisocyanatonaphthalene

Results and discussion

Any other information on results incl. tables

The remarks on the toxicokinetics of 1,5-Naphthylene diisocyanate (NDI) are based on physico-chemical properties of the compound and on toxicological data (Jäger, 2010). Experimental toxicokinetic studies were not performed.

 

Applicant's summary and conclusion