Registration Dossier
Registration Dossier
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EC number: 617-435-2 | CAS number: 83066-88-0
Dissociation constant
Administrative data
Link to relevant study record(s)
Description of key information
2.98, 20°C, potentiometric method, OECD 112, Wollerton
3.22(±0.03), 25±1°C, titration method, OECD 112, Chamberlain
Key value for chemical safety assessment
- pKa at 20°C:
- 2.98
Additional information
Two experimental values are available for 2-(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenoxy)propanoic acid. One is for the R-enantiomer (Wollerton), the second is for the racemate (Chamberlain); both are equivalent for this endpoint. While both reported values are in reasonable agreement, those from Wollerton are selected to maintain dataset consistency, and as they were collected under GLP. However, it is likely those reported by Chamberlain are the more accurate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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