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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
06 DEC 2017 - 25 APR 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
OECD test guideline, OECD 104 Vapour pressure
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
European Commission Regulations (EC) No. 440/2008 and No. 761/2009, A.4. Vapour pressure: Effusion method
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
effusion method: vapour pressure balance
Temp.:
20 °C
Vapour pressure:
0.013 Pa
Temp.:
25 °C
Vapour pressure:
0.026 Pa
Temp.:
50 °C
Vapour pressure:
0.52 Pa

The vapour pressure was measured in the temperature range of 10 °C to 40 °C. The measured vapour pressures at the corresponding temperatures are listed in the table below. After the measurement a mass loss of approx. 7 % (w/w) was determined.

Table: Measured vapour pressure and corresponding temperatures

 Temperature [°C]  Vapour pressure [hPa]
 10  n.e.
 15  4.0 x 10 -5*)
 20  1.3 x 10-4
 25  2.7 x 10-4
 30  5.0 x 10-4
 35  9.1 x 10-4
 40 1.6 x 10-3
 n.e. = not evaluable, *) = not included in the calculation of Antoine constants   

The data point measured at 15 °C was not included in the calculation of Antoine constants because it showed a deviation typical for measurements near the detection limit.

The values for 20, 25 and 50 °C are calculated, using the Antoine constants A, B and C as shown in the table below:

Table: Antoine parameters and extrapolated vapour pressures

 T [°C]  p [hPa]  log (p [hPa]) = A + B / (C + T [°C])
 20  1.3 x 10-4  A = 13.24134
 25  2.6 x 10-4  B = -5017.88
 50  5.2 x 10-3  C = 273.15

The following vapour pressure values for the test item were extrapolated from the experimental data (vapour pressure balance):

 T [°C]  p [hPa]  p [Pa]
 20  1.3 x 10-4  1.3 x 10-2
 25  2.6 x 10-4  2.6 x 10-2
 50  5.2 x 10-3  0.52
Conclusions:
The study was conducted under GLP according to OECD guideline 104 on the registered substance itself. The method is to be considered scientifically reasonable with no deficiencies in documentation or any deviations. Hence, the results can be considered as reliable to determine the vapour pressure of the test item.
Executive summary:

The vapour pressure of the test item was determined under GLP according to OECD 104 and EU method A.4 using the Effusion method, vapour pressure balance.

The following vapour pressure values for the test item were extrapolated from the experimental data (vapour pressure balance):

 T [°C]  p [hPa]  p [Pa]
 20  1.3 x 10-4  1.3 x 10-2
 25  2.6 x 10-4  2.6 x 10-2
 50  5.2 x 10-3  0.52

Description of key information

The vapour pressure of the test item was determined under GLP according to OECD 104 and EU method A.4 using the Effusion method, vapour pressure balance.

The following vapour pressure values for the test item were extrapolated from the experimental data (vapour pressure balance):

 T [°C]  p [hPa]  p [Pa]
 20  1.3 x 10-4  1.3 x 10-2
 25  2.6 x 10-4  2.6 x 10-2
 50  5.2 x 10-3  0.52

Key value for chemical safety assessment

Vapour pressure:
0.026 Pa
at the temperature of:
25 °C

Additional information