Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Hydrolysis:
Corsair Resin 5 was not assessed for hydrolysis as this study was technically not feasible. |
According to the guideline, the concentration of test samples should not exceed half the water solubility of the test substance or 0.01 M, whichever is lower. The water solubility of the test substance is < 1 mg/l. No analytical method was available to support the hydrolysis test at this low concentration level. The test on the hydrolysis of the test substance could therefore not be performed.
Ready Biodegradability:
Corsair Resin 5 was not readily biodegradable (1% after 30 days) under the conditions of the modified Sturm test (CO2 evolution test) that has been performed. However, the negative result of the available biodegradation study may be due to the fact that the tested concentration was far above the maximum water solubility. Thus, in view of lack of the optimal contact between the test substance and the medium in the present Modified Sturm test, no definitive conclusions can be drawn with respect of biodegradability of the test substance.
Adsorption/Desorption coefficient:
Since it was not possible to determine the Koc and log Koc values of the test substance using the HPLC method, the QSAR calculation method was applied. Based on the water solubility of the test substance (<2.3x10 -4 g/L) and its structural formula, the compound was classified as “predominantly hydrophobic”. For this chemical class, the log Koc is given as: logKoc = 0.81 x logPow + 0.10
The logarithm of the partition coefficient (log Pow) of one component of the test substance (i.e. the single string fatty acid amide using a modified structural formula) was calculated to be 7.46. Using this value, the Koc of this component of the test substance is calculated to be 1.38 x 106 and the corresponding log Koc = 6.14.
Considering that the alkyl chains in the modified structural formula were much shorter than in the original structure (C10 instead of C40), the real values for log Powand log Koc for the monomer are expected to be even higher.
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