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Diss Factsheets
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EC number: 952-967-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Remarks:
- Abiotic transformation in water as a function of pH
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1 hour
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- It is suspected that the substance will degrade under acidic conditions to form water soluble sodium salts and insoluble titanium oxides.
This specific experiment was conducted to look for evidence of this process.
In addition, literature searches were perofrmed for stability in acid
This work has been performed to support the avoidance of animal testing by demonstrating degradation to titanium dioxide and sodium chloride. - Reason / purpose for cross-reference:
- assessment report
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Sodium titanate was mixed in distilled water and in molar HCl. After mixing for one hour at room temperature, the liquids were filtered and washed to leave a clear filtrate and residual solid on the filters. The filtrates were dried to determine if any soluble fractions and the solids formed from solution were weighed to give an approximate quantitative result.
100 mg of sodium titanate mixed in 100 ml of distilled water or 1M HCl at 20 C - GLP compliance:
- no
- Radiolabelling:
- no
- Analytical monitoring:
- no
- Duration:
- 1 h
- pH:
- 1
- Temp.:
- 20 °C
- Initial conc. measured:
- < 1 mg/L
- Remarks:
- From loading of 1000 mg/l, ca 300 mg NaCl is estimated to have been formed
- Duration:
- 1 h
- pH:
- 10
- Temp.:
- 20 °C
- Initial conc. measured:
- < 1 mg/L
- Remarks:
- From loading of 1000 mg/l, ca 200 mg NaCl is estimated to have been formed
- No.:
- #1
- No.:
- #2
- Details on hydrolysis and appearance of transformation product(s):
- The two degradation products are reported in literature and observations confirmed appearance of insoluble white solid and soluble crytalline residues.
- Conclusions:
- This experiment indicates that there is formation of soluble salts from mixing in excess acid or mixing in dilute forms in distilled water.
In terms of Na solubility, loading at 1000 mg/l resulted in ca 120 mg Na (300 mg NaCl) when mixed in acid and ca 120 mg Na (200 mg NaOH) in deionised water. It is assumed that a trace of Ti will have passed through filters, but with reported Ti solubility < 1 mg/l, this will be negligible.
Under both sets of conditions, sodium seems to dissociate to form soluble salts.
Reference
100 mg of sodium titanate mixed in 100 ml of distilled water or 1M HCl at 20 C resulted in 20 mg and 30 mg of solid crystallising from filtrate respectively; the acid treatment clearly led to a higher yield, suggesting more dissociation. However, even the 20 mg formed with distilled water implied some degradation.
In terms of Na solubility, loading at 1000 mg/l resulted in ca 120 mg Na (300 mg NaCl) when mixed in acid and ca 80 mg Na (200 mg NaCl) in deionised water. It is assumed that a trace of Ti will have passed through filters, but with reported Ti solubility < 1 mg/l, this will be negligible.
Further work is needed to identify the solid residues on the filter and crystallising from the filtrate. It is also considered important to work on environmentally relevant concentrations to determine if the rate of dissociation / hydrolysis is faster and/or more complete.
The proposed reaction scheme is:
Na2O3Ti + 2HCl to 2NaCl + TiO3H2 to TiO2 + H2O + 2NaCl
The theoretical route of degradation is less clear in deionised watr, but is likely to result in formation of sodium hydroxide
Theoretical yield of NaCl from 0.1 g sodium titanate (0.0007 moles) with excess 0.1 mole hydrochloric acid is ca 80 mg
Description of key information
The substance is an inorganic compound and is not expected to undergo true hydrolysis in the environment but it is known to demonstrate some abiotic degradation with the formation of soluble salts (eg sodium chloride in hydrochloric acid).
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.