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EC number: 852-824-2 | CAS number: 1404220-73-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation: aquatic / sediment
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- other: model results
- Title:
- EPISUITE 4.0 Report on Diisodecylpheny Phosphite (DDPP; CAS 25550-98-5)
- Author:
- US EPA
- Year:
- 2 009
- Bibliographic source:
- US EPA
- Report date:
- 2009
- Reference Type:
- other: model result
- Title:
- EPISUITE 4.0 Report on Triisodecyl Phosphite (TDP; CAS 25448-25-3)
- Author:
- US EPA
- Year:
- 2 010
- Bibliographic source:
- US EPA
- Reference Type:
- other: model result
- Title:
- EPISUITE 4.0 Report on Diphenyl isodecyl Phosphite (DPDP; CAS 26544-23-0)
- Author:
- US EPA
- Year:
- 2 010
- Bibliographic source:
- US EPA
Materials and methods
- Principles of method if other than guideline:
- Modeled results using EPISUITE 4.0 (BCFBAF v.3.00) for the 3 constituent chemicals of the substance - diisodecylphenyl phosphite (DDPP), triisodecyl phosphite (TDP), and diphenyl isodecyl phosphite (DPDP).
- GLP compliance:
- no
Test material
- Reference substance name:
- Diisodecyl phenyl phosphite
- EC Number:
- 247-098-3
- EC Name:
- Diisodecyl phenyl phosphite
- Cas Number:
- 25550-98-5
- Molecular formula:
- C26H47O3P
- IUPAC Name:
- Phosphorous acid, diisodecyl phenyl ester
- Details on test material:
- 3 constituent chemicals of the substance - diisodecylphenyl phosphite (DDPP), triisodecyl phosphite (TDP), and diphenyl isodecyl phosphite (DPDP).
Constituent 1
Results and discussion
Bioaccumulation factor
- pH:
- 7
- Type:
- BCF
- Value:
- 606.5 L/kg
- Remarks on result:
- not measured/tested
Any other information on results incl. tables
-------------------------------- BCFBAF v3.00 --------------------------------
DDPP Results
Summary Results: Log BCF (regression-based estimate): 2.39 (BCF = 245 L/kg wet-wt)
Biotransformation Half-Life (days) : 27.6 (normalized to 10 g fish)
Log BAF (Arnot-Gobas upper trophic): 4.21 (BAF = 1.63e+004 L/kg wet-wt)
Log Kow (experimental): not available from database
Log Kow used by BCF estimates: 9.32
Equation Used to Make BCF estimate: Log BCF = -0.49 log Kow + 7.554 + Correction Correction(s): Value Alkyl chains (8+ -CH2- groups) -0.596 Estimated
Log BCF = 2.389 (BCF = 244.7 L/kg wet-wt)
--------------------------------- BCFBAF v3.00 --------------------------------
TDP Results
Summary Results: Log BCF (regression-based estimate): 1.52 (BCF = 33.3 L/kg wet-wt)
Biotransformation Half-Life (days) : 230 (normalized to 10 g fish)
Log BAF (Arnot-Gobas upper trophic): 2.71 (BAF = 509 L/kg wet-wt)
Log Kow (experimental): not available from database
Log Kow used by BCF estimates: 12.31
Equation Used to Make BCF estimate: Log BCF = -0.49 log Kow + 7.554 + Correction (no use)
Log BCF = 1.522 (BCF = 33.27 L/kg wet-wt)
-------------------------------- BCFBAF v3.00 --------------------------------
DPDP Results
Summary Results: Log BCF (regression-based estimate): 2.78 (BCF = 607 L/kg wet-wt)
Biotransformation Half-Life (days) : 15.5 (normalized to 10 g fish)
Log BAF (Arnot-Gobas upper trophic): 4.38 (BAF = 2.4e+004 L/kg wet-wt)
Log Kow (experimental): not available from database
Log Kow used by BCF estimates: 8.52
Equation Used to Make BCF estimate: Log BCF = -0.49 log Kow + 7.554 + Correction Correction(s): Value Alkyl chains (8+ -CH2- groups) -0.596 Estimated
Log BCF = 2.783 (BCF = 606.5 L/kg wet-wt)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- BCFs of 33.27 to 606.5 L/kg wet weight were calculated using the BCFBAF v3.0 program. This model use the log Kow in the following equation: Log BCF = -0.49 log Kow + 7.554 + Correction (varies).This substance does not meet the bioaccumulation criteria (BCF) of 2000 L/kg. Therefore, it is not a PBT.
- Executive summary:
BCFs of 33.27 to 606.5 L/kg wet weight were calculated using the BCFBAF v3.0 program. This model use the log Kow in the following equation: Log BCF = -0.49 log Kow + 7.554 + Correction (varies).
This result is likely to overpredict the bioaccumulation potential of these phosphites given the size and molecular weight of the molecules and also due to the fact that it is not clear that the model is valid at such a high Kow value. Regardless, the predicted values are well below the PBT criterion on 2000 L/kg. Further, these results do not consider the fact that this substance rapidly hydrolyses and that the hydrolysis products have a low bioaccumulation potential and a readily biodegradable.
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