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EC number: 939-690-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Readily biodegradable: 60-63 % based on parallel A in two independent experiments (CO2 evolution) in 28 days
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
A GLP study with Multi constituent ester of pentaerythritol 2-ethylhexanoate was conducted under aerobic conditions according to OECD guideline 301B using non-adapted, domestic activated sludge as inoculum (Desmares-Koopmans, 2013). The Total Organic Carbon (TOC) content of the substance was determined to be 69%. The test substance was tested in duplicate at approximately 18 mg/l, corresponding to 12 mg TOC/l.
Based on the TOC content the ThCO2 of the substance was calculated to be 2.54 mg CO2/mg.
Since in first experiment the difference in percentage of biodegradation between the two test bottles was more than 20%, a second experiment was performed. The findings of the first experiment were confirmed by the second experiment.
In both experiments weighed amounts were added to the 2-litres test bottles containing medium with microbial organisms and mineral components. To this end, 10-20 ml of Milli-RO water was added to each weighing bottle containing the test substance. After vigorous mixing (vortex) the resulting suspension was added quantitatively to the test medium. The test solutions were continuously stirred during the test, to ensure optimal contact between the test substance and the test organisms. Test duration was 28 days (last CO2-measurement on the 29th day).
In the 1st experiment the relative biodegradation values calculated from the measurements performed during the test period revealed 63% and 35% biodegradation of Multi constituent ester of pentaerythritol 2-ethylhexanoate, for test bottle A and B, respectively.
In the 2nd experiment the relative biodegradation values calculated from the measurements performed during the test period revealed 60% and 24% biodegradation of Multi constituent ester of pentaerythritol 2-ethylhexanoate for test bottle A and B, respectively.
Since, the batch of Multi constituent ester of pentaerythritol 2-ethylhexanoate consisted of a mixture of structurally similar chemicals, it was anticipated that a sequential biodegradation of the individual structures took place. Therefore, the 10-day window was not applied to interpret the results of the test and the criterion for ready biodegradability was met in test bottle A of both experiments.
Percentage biodegradation in the toxicity controls on Day 14 was 39% and 14% in experiment 1 and 2, respectively, thus only in experiment 1 the 25% threshold for inhibition was met. However, one of the test bottles reached 60% biodegradation, which indicated that the test substance did not inhibit microbial activity. Therefore it was concluded, that Multi constituent ester of pentaerythritol 2-ethylhexanoate was found not to inhibit microbial activity.
Except that the acceptability criteria adressing a maximum variation of 20% between test bottles in an experiment was not met in both experiments, which was considered to have no adverse effect on the test, all criteria for acceptability of the test were met. Therefore, this study was considered to be valid.
In conclusion, Multi constituent ester of pentaerythritol 2-ethylhexanoate was designated as readily biodegradable.
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