Registration Dossier
Registration Dossier
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EC number: 700-604-0 | CAS number: 947701-81-7
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Due to the nature of the end use of the substance (cosmetic ingredient) the registered substance UC was not used for animal testing. A surrogate substance Undecenyl methoxycrylene has been identified as the most suitable substance to conduct the animal studies on, therefore the classification for UC has been based on the results from Undecenyl methoxycrylene.
Migrated from Short description of key information:
LOCAL LYMPH NODE ASSAY IN THE MOUSE 2600/0013:
Undecenyl methoxycrylene - this substance has been identified as the most appropriate 'read-across' substance.
OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
According to the Klimisch Scale - Reliability 1
Justification for classification or non-classification
From the data from the key study (Undecenyl methoxycrylene: LOCAL LYMPH NODE ASSAY IN THE MOUSE ), a Stimulation Index of 0.72 was achieved. A positive reaction is identified if the Stimulation Index equals >=3. Therefore, according to these results UC is considered to be non-sensitising.
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