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EC number: 442-480-8 | CAS number: 182893-11-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20 March 2002 - 21 March 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- GLP compliance:
- yes
- Type of method:
- static method
- Temp.:
- 9.31 °C
- Vapour pressure:
- 495 Pa
- Temp.:
- 15.48 °C
- Vapour pressure:
- 632 Pa
- Temp.:
- 20.86 °C
- Vapour pressure:
- 790 Pa
- Transition / decomposition:
- no
- Conclusions:
- The vapour pressure at 20°C was determined to be: p (20°C) = 761 ± 30 Pa = 5.71 ± 0.23 mm Hg
- Executive summary:
The determination of the vapour pressure of was based on the following guidelines:
European Economic Community (EEC), EEC directive 92/69 EEC, Part A, Methods for the determination of physico-chemical properties, A.4 "Vapour pressure", EEC Publication No. L383, December 1992.
Organisation for Economic Co-operation and Development (OECD), OECD guidelines for testing chemicals, Guideline NO.104: "Vapour pressure curve", July 27, 1995.
Using the Static Technique, the vapour pressure at 20°C was determined to be: P (20°C) = 761 ± 30 Pa = 5.71 ± 0.23 mm Hg
Based on the structural formula of Trigonox R-938, a lower vapour pressure was expected. Probably the relative high vapour pressure was caused by the presence of water and 3-methyl-2-butanone.
Reference
Based on the structural formula, a lower vapour pressure was expected. Probably the relative high vapour pressure was caused by the presence of water and 3-methyl2 -butanone.
Fitting these data using the least squares method gives a value of 761 Pa for the vapour pressure of the test substance at 20°C with 23 Pa for 2σn-1 (i.e. 3.0%). The maximum deviation between the fit and the data points is always less than about 0.6%. Errors made in estimating the mean value per temperature series are up to 1.2%. So a value of 30 Pa (i.e. 3.9%) is a reasonable value for the uncertainty in the final result.
The vapour pressure was determined to be: p (20°C) = 761 ± 30 Pa = 5.71 ± 0.23 mm Hg
Description of key information
The vapour pressure at 20°C was determined to be: p (20°C) = 761 ± 30 Pa = 5.71 ± 0.23 mm Hg. The Notox VP report states: “Based on the structural formula of Trigonox R-938, a lower vapour pressure was expected. Probably the relative high vapour pressure was caused by the presence of water and 3-methyl2-butanone.” This VP is too high, since it is partly based on exposure to non-hazardous impurities. Therefore, exposure to the peroxide is overestimated when using this VP.
The test method for determination of vapour pressure described in the test guideline A.4 of 2008/440/EC was replaced by a theory based evaluation as a reliable determination is not possible. The registered substance exists as solution in a stabiliser due to its reactivity.
It is shown by critical component assessment based on ECHA methodology that 1,2-Dimethylpropylidene dihydroperoxide is the critical component for inhalation exposure based on the VP, concentration in the mixture and DNEL. With Epiwin the following VPs are calculated for the substances as such: T3 and T4: 42.9 Pa, 25°C and 0.0892 Pa, 25°C (Modified Grain method). The VP for pure H2O is 2338 Pa at 20°C, MIKP 5500 Pa at 20°C, H2O2 299 Pa at 25°C and DMP 0.13 Pa at 20 °C.
Applying Raoult’s law (using mol fractions and individual saturated vapor pressures). The contribution of each component is then calculated. T3, T4, H2O2, H2O, DMP, MIPK, as components (total 100.2 wt%, Notox report). The following results are found (total pressure = 7.61 mbara (5.41 Mm Hg)) 20°C:
Type 3, Type 4: 2.325 mbara
H2O2: 0.149 mbara
H2O: 4.518 mbara
DMP: 0.003 mbara
MIPK: 0.615 mbara
The VP at 20°C for 2.325 mbara, or 232.5 Pa. In a similar way it was calculated that at 40°C the VP is 7.1 mbara, or 710 Pa, this value will be used in the Chesar risk assessment
Key value for chemical safety assessment
- Vapour pressure:
- 710 Pa
- at the temperature of:
- 40 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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