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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Test procedure in accordance to national standard methods.
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
Supplier: Tokyo Kasai Co
Analytical method:
other: gas-liquid chromatography with flame ionization detection
Key result
Type:
log Pow
Partition coefficient:
0.97
Temp.:
20 °C
pH:
ca. 7
Remarks on result:
other: pH determinations are not reported.
Details on results:
Value is the mean of four determinations.
Conclusions:
The octanol-water partition coefficient was determined to be 0.97 at 20 deg C.
Executive summary:

Th octanol-water partition coefficient was tested OECD 107 (shake flask method)  and determined to be 0.97 at 20 °C.

Description of key information

The log Kow of HPMA is 0.97 (OECD Guideline 117/EU Method A.8; HPLC method).

Key value for chemical safety assessment

Log Kow (Log Pow):
0.97
at the temperature of:
20 °C

Additional information