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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

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Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
other aquatic crustacea: Daphnid
Test type:
other: (Q)SAR
Water media type:
freshwater
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
37.698 mg/L
Validity criteria fulfilled:
yes
Remarks:
Aliphatic Amines: Maximum LogKow: 5.0 (Daphnid LC50)
Conclusions:
Estimated LC50 (96 h) : 37 mg/L
Intermediate substance is estimated to be harmful to aquatic invertebrates (acute toxicity).
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1997-07-08 1997-07-10
Reliability:
2 (reliable with restrictions)
Qualifier:
according to guideline
Guideline:
other: NF EN ISO 6341
GLP compliance:
no
Specific details on test material used for the study:
Bicrist OHquinu mélange reliquats divers 1ère partie
Analytical monitoring:
no
Vehicle:
not specified
Test organisms (species):
Daphnia magna
Details on test organisms:
Third generation, at least third spawn
Test type:
not specified
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
48 h
Hardness:
245.6 mg CaCO3/L
pH:
7.31
Reference substance (positive control):
yes
Remarks:
Potassium dichromate
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Results with reference substance (positive control):
Potassium dichromate CL50-24h: 0.64mg/L
Conclusions:
CL50-48h >100 mg/L

Intermediate substance is not estimated to be toxic to aquatic invertebrates (acute toxicity).

Description of key information

ECOSAR 1.11: Daphnid: LC50 (48h): 37 mg/L

Experimental data : Daphnid LC50 (48h) >100 mg/L

Key value for chemical safety assessment

Additional information

Experimental data is considered :

Intermediate substance is not estimated to be toxic to aquatic invertebrates (acute toxicity).