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EC number: 203-293-5 | CAS number: 105-38-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 February - 12 March 1997
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Remarks:
- study acc. to guideline from 1996, some parameters are not reported
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- ISO 14593:1999 (Water quality - Evaluation of ultimate aerobic biodegradability of organic compounds in aqueous medium - Method by analysis of inorganic carbon in sealed vessels (CO2 headspace test))
- Version / remarks:
- draft version 1996
- Deviations:
- not specified
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 310 (Ready Biodegradability - CO2 in Sealed Vessels (Headspace Test)
- Version / remarks:
- 2014
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Vinyl propionate
- EC Number:
- 203-293-5
- EC Name:
- Vinyl propionate
- Cas Number:
- 105-38-4
- Molecular formula:
- C5H8O2
- IUPAC Name:
- ethenyl propanoate
- Reference substance name:
- Unknown impurities.
- Molecular formula:
- Not available as unknown impurities.
- IUPAC Name:
- Unknown impurities.
- Test material form:
- liquid: volatile
Constituent 1
impurity 1
- Specific details on test material used for the study:
- Storage: with exclusion of oxygen, max. 25°C
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- - Source: activated sludge, non-adapted, from laboratory sewage treatment plants run with domestic and synthetic waste water
- Preparation of inoculum for exposure: no details reported
- Pretreatment: no details reported
- Concentration of sludge: 4 mg/l dry matter in the final mixture - Duration of test (contact time):
- ca. 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 29 mg/L
- Based on:
- test mat.
- Initial conc.:
- 17.3 mg/L
- Based on:
- other: ThOC
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- inorg. C analysis
- Details on study design:
- TEST PRINCIPLE
The test substance, a defined test medium and the inoculum are incubated under standardised conditions. If biodegradation takes place, the bacteria produce CO2 from the organically bound carbon.
Every 7 days NaOH is injected in a part of the replicate flasks. Afterwards the biologically produced CO2 can be determined as inorganic carbon present in the solution.
The amount of total inorganic carbon (TIC) in relation to the applied amount of total organic carbon (TOC), is used to calculate the biodegradability.
TEST CONDITIONS
- Composition of test medium: not reported
- Test temperature: not reported
- pH: pH at day 28 was 6.9
- Continuous darkness: not reported
TEST SYSTEM
- Test flasks: 160 ml test flasks containing 100 ml test solution
- Test performed in triplicate (three test flasks)
CONTROL AND BLANK SYSTEM
BW: blind
NaOH - BW: NaOH, blind subtracted
KS: control substance (aniline, 26.7 mg/l, ThOC 20.9 mg/l)
PS: test substance (vinyl propionate, 29.0 mg/l, ThOC 17.3 mg/l)
IH: inhibition control (with test substance 29.0 mg/l, ThOC 17.3 mg/l and aniline 26.7 mg/l, ThOC 20.9 mg/l)
SAMPLING
Samples were taken on day 7, 14, 21 and 28.
Total inorganic carbon measurements were performed on samples from the control flasks (KS) and from the test substance flasks (PS).
Total inorganic carbon measurements and DOC-measurements were performed on samples from the blind flasks (BW) as well as NaOH minus blind flasks (NaOH - BW).
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (inorg. C analysis)
- Value:
- 92
- Sampling time:
- 28 d
- Remarks on result:
- other: mean of three test flasks, test flask 1: 90%, test flask 2: 92%, test flask 3: 93%
- Details on results:
- - Duration of adaptation phase: < 7 days
- Duration of degradation phase: not determinable (plateau phase not yet reached at the end of the test)
Measured TIC values (mg/l) after 28 d, mean of three test flasks
NaOH-BW: 1.6 mg/l
BW: 3.8 mg/l
KS: 20.3 mg/l
PS: 19.5 mg/l
IH: 37.8 mg/l
pH:
BW: 7.3
KS: 6.9
PS: 6.9
IH: 6.7
Any other information on results incl. tables
Validity criteria:
The control substance reached >60% biodegradation based on TIC after 14 days, thus confirming suitability of inoculum and test conditions.
In the inhibition control, 80 -90% biodegradation based on TIC was reached, i.e. no inhibition was observed at the test concentration used.
Total inorganic carbon (TIC) content (mg/l) in blind test flasks after 28 days was < 15% of the amount applied in the test substance flasks (mg ThIC/l)
Maximum deviation in % degradation between the flasks was <20%.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- A 28-d CO2 headspace test (ISO/CD 14593) using activated sludge of laboratories sewage treatment plants indicated that vinyl propionate (CAS 105-38-4) reached a biodegradation of 92% based on inorganic carbon analysis. The substance reached the pass level of 60% for ready biodegradability within the 10-d window and, therefore, can be termed as readily biodegradable.
- Executive summary:
A 28-d CO2 headspace test (ISO/CD 14593) using activated sludge of laboratories sewage treatment plants indicated that vinyl propionate (CAS 105-38-4) reached a biodegradation of 92% based on inorganic carbon analysis. The substance reached the pass level of 60% for ready biodegradability within the 10-d window and, therefore, can be termed as readily biodegradable.
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